Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Larsen Alf D"'
Autor:
Mochizuki, Diane Y., Eisenman, June R., Conlon, Paul J., Larsen, Alf D., Tushinski, Robert J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1987 Aug 01. 84(15), 5267-5271.
Externí odkaz:
https://www.jstor.org/stable/30018
Autor:
Sean Luhr, David Cosman, Linda S. Park, Philip J. Morrissey, Larsen Alf D, Unja Martin, Rick Sorensen
Publikováno v:
Proceedings of the National Academy of Sciences. 89:4295-4299
A cDNA clone (clone 71) that encodes a low-affinity receptor for murine granulocyte-macrophage colony-stimulating factor (GM-CSF) has been isolated by direct expression. This molecule is the homologue of the human GM-CSF receptor alpha subunit, altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc64a385ebee17d9893b3de268d8f23
https://doi.org/10.1073/pnas.89.10.4295
https://doi.org/10.1073/pnas.89.10.4295
Publikováno v:
The Journal of Experimental Medicine
IFN-gamma mRNA levels in human neonatal blood mononuclear cells or highly purified T cells were markedly lower than those of adult cells after incubation with Con A and PMA. In contrast, IL-2, IL-2-R, and T3 delta chain mRNA levels were kinetically a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2e925a48ed7a5feed2f52ae4b1e1ed
http://europepmc.org/articles/PMC2188077
http://europepmc.org/articles/PMC2188077
Publikováno v:
Proceedings of the National Academy of Sciences. 81:6481-6485
The cell surface receptor for interleukin 2 plays a central role in the biology of this T-cell growth factor. A combination of affinity chromatography, high-performance liquid chromatography, and NH2-terminal protein sequencing was used to purify and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82a11a9dd7f8583371f1602906ed313
https://doi.org/10.1073/pnas.81.20.6481
https://doi.org/10.1073/pnas.81.20.6481
Autor:
Paul J. Conlon, Christopher S. Henney, Douglas P. Cerretti, Virginia L. Price, Steven Gillis, Carl J. March, Shirley R. Kronheim, Larsen Alf D, Bruce Mosley, Kenneth H. Grabstein, Thomas P. Hopp, David Cosman, Gary Braedt
Publikováno v:
Nature. 315:641-647
Two distinct but distantly related complementary DNAs encoding proteins sharing human interleukin-1 (IL-1) activity (termed IL-1 alpha and IL-1 beta), were isolated from a macrophage cDNA library. The primary translation products of the genes are 271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0de7ff463d80a79949012901b888382
https://doi.org/10.1038/315641a0
https://doi.org/10.1038/315641a0
Autor:
Kenneth H. Grabstein, Kathryn S. Prickett, Christopher B. Wilson, Michael J. Weaver, David B. Lewis, Larsen Alf D
Publikováno v:
Proceedings of the National Academy of Sciences. 85:9743-9747
Interleukin 4 (IL-4) is secreted by activated T cells and pleiotropically modulates both B- and T-lymphocyte function. In murine helper (CD4+) T-cell clones IL-4 production appears to be regulated independently of interferon gamma and interleukin 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c7d95b7e8dc6c36fc732fb0871537f
https://doi.org/10.1073/pnas.85.24.9743
https://doi.org/10.1073/pnas.85.24.9743
Publikováno v:
Proceedings of the National Academy of Sciences. 84:5267-5271
A murine in vitro assay was developed to measure potentiation of a proliferative response to suboptimal concentrations of the hematopoietic regulatory molecule granulocyte/macrophage colony-stimulating factor by an immature bone marrow population. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3484b4e72a2f5f1161147af02a53fe3
https://doi.org/10.1073/pnas.84.15.5267
https://doi.org/10.1073/pnas.84.15.5267
Autor:
Dirk M. Anderson, Conlon Iii Paul J, Kenneth H. Grabstein, David J. Cosman, Michael A. Cantrell, Larsen Alf D, Douglas P. Cerretti, Virginia L. Price
Publikováno v:
Science. 232:506-508
Monocytes are a subpopulation of peripheral blood leukocytes, which when appropriately activated by the regulatory hormones of the immune system, are capable of becoming macrophages--potent effector cells for immune response to tumors and parasites.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af317c1e7e7312d9048bb0fc65f58d92
https://doi.org/10.1126/science.3083507
https://doi.org/10.1126/science.3083507
Autor:
Larsen, Alf D., Sypherd, Paul S.
Publikováno v:
Journal of Bacteriology; February 1974, Vol. 117 Issue: 2 p432-438, 7p
Publikováno v:
Molecular immunology. 24(5)
An EBV transformed B-cell line was derived from peripheral blood cells from a single donor. B-cell clones were isolated from that line and analyzed for transcription of IL-1 genes, production of biologically detectable IL-1 and antigen presenting cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d65d3d9ce8e7f2221f7e1ca042f951
https://pubmed.ncbi.nlm.nih.gov/2821386
https://pubmed.ncbi.nlm.nih.gov/2821386