Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lars V. Kristiansen"'
Autor:
Stephen T. Holgate, Hans Lehrach, Alison Harvey, Lars V. Kristiansen, Barbara Prainsack, Angela Brand, Aarno Palotie
Publikováno v:
Europe PubMed Central
New Biotechnology, 29(6), 625-633. Elsevier
New Biotechnology
New Biotechnology, 29(6), 625-633. Elsevier
New Biotechnology
Personalised medicine promises prediction, prevention and treatment of illness that is targeted to individuals’ needs. New technologies for detailed biological profiling of individuals at the molecular level have been crucial in initiating the move
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43e4946476ec66fe3310b38e95f09da
https://doi.org/10.1016/j.nbt.2012.03.009
https://doi.org/10.1016/j.nbt.2012.03.009
Publikováno v:
NeuroReport. 22:935-938
Administration of noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist phencyclidine to rats on postnatal days 7, 9, and 11 induces apoptosis in prefrontal cortex and hippocampus. In adulthood, these animals display cognitive impairment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f71382d2ba1669a110351e2817a0eb
https://doi.org/10.1097/wnr.0b013e32834d2ef7
https://doi.org/10.1097/wnr.0b013e32834d2ef7
Publikováno v:
Acta Psychiatrica Scandinavica. 120:345-354
Objective: To describe structural and biochemical evidence from postmortem brains that implicates the reciprocal connections between the mediodorsal thalamic nucleus and the prefrontal cortex in cognitive symptoms of schizophrenia. Method: The estima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee4fec4ed49c13672c2de2f0b667806
https://doi.org/10.1111/j.1600-0447.2009.01447.x
https://doi.org/10.1111/j.1600-0447.2009.01447.x
Autor:
Kakanahalli Nagaraj, Lars V. Kristiansen, Adam Skrzynski, Carlos Castiella, Luis Garcia-Alonso, Michael Hortsch
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
L1-cell adhesion molecule (L1-CAM) belongs to a functionally conserved group of neural cell adhesion molecules that are implicated in many aspects of nervous system development. In many neuronal cells the adhesive function of L1-type CAMs induces cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d0abfbc712775e96c6e3b45f2e7277
https://doi.org/10.1093/hmg/ddp325
https://doi.org/10.1093/hmg/ddp325
Altered Vesicular Glutamate Transporter Expression in the Anterior Cingulate Cortex in Schizophrenia
Autor:
Vahram Haroutunian, James H. Meador-Woodruff, Akin Oni-Orisan, Lars V. Kristiansen, Robert E. McCullumsmith
Publikováno v:
Biological Psychiatry. 63:766-775
Background Schizophrenia is a chronic, severe mental illness with profound emotional and economic burdens for those afflicted and their families. An increasing number of studies have found that schizophrenia is marked by dysregulation of glutamatergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5480d08417096553a45f3664862927a0
https://doi.org/10.1016/j.biopsych.2007.10.020
https://doi.org/10.1016/j.biopsych.2007.10.020
Publikováno v:
Molecular Psychiatry. 11:737-747
Abnormal expression of the N-methyl-D-Aspartate (NMDA) receptor and its interacting molecules of the postsynaptic density (PSD) are thought to be involved in the pathophysiology of schizophrenia. Frontal regions of neocortex including dorsolateral pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268b7cc06b402071fe61e24b8bc9b66a
https://doi.org/10.1038/sj.mp.4001844
https://doi.org/10.1038/sj.mp.4001844
Publikováno v:
Current Psychosis & Therapeutics Reports. 4:27-34
Schizophrenia is a severe mental illness affecting millions of people worldwide, with a substantial impact on patients, family, and society. Recent studies have established support for a hypothesis of abnormal glutamatergic neurotransmission in speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::410f13e4e794073a13785d7920acc6ad
https://doi.org/10.1007/bf02629411
https://doi.org/10.1007/bf02629411
Dysregulated glutamate neurotransmission has been implicated in the pathophysiology of schizophrenia. In particular, hypofunction of the NMDA glutamate receptor has been proposed to play an important role in mediating cognitive deficits in patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba09aa9490c93470ded0ac8eba285775
https://europepmc.org/articles/PMC2868940/
https://europepmc.org/articles/PMC2868940/
Publikováno v:
Synapse (New York, N.Y.). 64(7)
Several lines of evidence implicate aberrant glutamate neurotransmission in the pathophysiology of schizophrenia. In particular, compromised signaling through the N-methyl-D-aspartate (NMDA) receptor has been linked to positive, negative, and cogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e16f95153e4dfed6be13ad28ab8d6bf
https://pubmed.ncbi.nlm.nih.gov/20175224
https://pubmed.ncbi.nlm.nih.gov/20175224
Autor:
Lars V, Kristiansen, Michael, Hortsch
Publikováno v:
Advances in experimental medicine and biology. 663
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05eb98e1572768de27aca18eb2178faa
https://pubmed.ncbi.nlm.nih.gov/20017035
https://pubmed.ncbi.nlm.nih.gov/20017035