Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lars Tykocinski"'
Autor:
Lars Tykocinski, Carolin Birr, Marc-Steffen Raab, Stefan Krienke, Petra Schiller, Christine Tucher, Hanns Martin Lorenz, Norbert Blank, Laura Claßen, Felix Wiedmann, Martin Schiller
Publikováno v:
European Journal of Immunology. 47:1535-1549
Cell activation and apoptosis lead to the formation of extracellular vesicles (EVs) such as exosomes or microvesicles (MVs). EVs have been shown to modulate immune responses; recently, MVs were described to carry microRNA (miRNA) and a role for MVs i
Autor:
Franziska V. Kraus, Hanns-Martin Lorenz, Mónica Abreu, Rainer Saffrich, André P. Meyer, Thomas Giese, Mark Kriegsmann, Rui A. Carvalho, Roger Sandhoff, Karel D. Klika, Volker Eckstein, M. Margarida Souto-Carneiro, Lina Carvalho, Richard Jennemann, Lars Tykocinski
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)REFERENCES. 72(12)
OBJECTIVE CD8+ T cells contribute to rheumatoid arthritis (RA) by releasing proinflammatory and cytolytic mediators, even in a challenging hypoxic and nutrient-poor microenvironment such as the synovial membrane. This study was undertaken to explore
Autor:
Lars Tykocinski, Hanns-Martin Lorenz, T. Tretter, Bastian Resch, Panagiotis Gitsioudis, Patrick Horn, Rainer Saffrich
Publikováno v:
Autoimmune inflammation.
Background Multipotent mesenchymal stromal cells (MSC) are well known for their multilineage potential and immunosuppressive properties. They might be a useful alternative for treatment of chronic inflammatory diseases. Little is known however, in ho
Autor:
Margareta P. Correia, Ana Stojanovic, Katharina Bauer, Dilafruz Juraeva, Lars Tykocinski, Hanns-Martin Lorenz, Benedikt Brors, Adelheid Cerwenka
Publikováno v:
The Journal of Immunology. 200:124.6-124.6
CD8+ T cells are considered prototypical cells of adaptive immunity. Here, we uncovered a distinct CD8+ T cell population, expressing the activating NK receptor, NKp30, in peripheral blood of healthy individuals. We revealed that IL-15 could de novo
Publikováno v:
Annals of the Rheumatic Diseases. 73:A91.1-A91
Background and Objectives Synovial fibroblasts (SF) are key players in pathogenesis and progression of rheumatoid arthritis (RA). A cross-talk between immune cells and SF is suggested to contribute to chronification of the disease. RA-SF can be found