Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lars Pelz"'
Autor:
Tanya Dogra, Lars Pelz, Julia D. Boehme, Jan Kuechler, Olivia Kershaw, Pavel Marichal-Gallardo, Maike Baelkner, Marc D. Hein, Achim D. Gruber, Dirk Benndorf, Yvonne Genzel, Dunja Bruder, Sascha Y. Kupke, Udo Reichl
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Influenza A virus (IAV) defective interfering particles (DIPs) are considered as new promising antiviral agents. Conventional DIPs (cDIPs) contain a deletion in the genome and can only replicate upon co-infection with infectious standard vir
Externí odkaz:
https://doaj.org/article/14074a084c1e479b80e20d113a9f8b14
Autor:
Lars Pelz, Elena Piagnani, Patrick Marsall, Nancy Wynserski, Marc Dominique Hein, Pavel Marichal-Gallardo, Sascha Young Kupke, Udo Reichl
Publikováno v:
Viruses, Vol 15, Iss 9, p 1872 (2023)
New broadly acting and readily available antiviral agents are needed to combat existing and emerging viruses. Defective interfering particles (DIPs) of influenza A virus (IAV) are regarded as promising options for the prevention and treatment of IAV
Externí odkaz:
https://doaj.org/article/6e9ede8ffa674c76984914b8a83d92f0
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009357 (2021)
Cell culture-derived defective interfering particles (DIPs) are considered for antiviral therapy due to their ability to inhibit influenza A virus (IAV) production. DIPs contain a large internal deletion in one of their eight viral RNAs (vRNAs) rende
Externí odkaz:
https://doaj.org/article/966bf3bc5b8e4f32b7114a566f90a7d9
Publikováno v:
Bioprocessing of Viral Vaccines ISBN: 9781003229797
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845005a9c83102e950b694865dd6d76d
https://doi.org/10.1201/9781003229797-6
https://doi.org/10.1201/9781003229797-6
Publikováno v:
Bioprocessing of Viral Vaccines ISBN: 9781003229797
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97828168cef1aff72725ff97b63c3575
https://doi.org/10.1201/9781003229797-5
https://doi.org/10.1201/9781003229797-5
Autor:
Tanya Dogra, Christopher B. Brooke, Udo Reichl, Fadi G. Alnaji, Sascha Young Kupke, Daniel Rüdiger, Yvonne Genzel, Lars Pelz
Publikováno v:
Journal of Virology
Defective interfering particles (DIPs) of influenza A virus (IAV) are naturally occurring mutants that comprise an internal deletion in one of their eight viral RNA (vRNA) segments, rendering them propagation-incompetent. Upon co-infection with infec
Autor:
Friedemann Weber, Michael Winkler, Najat Bdeir, Ulrike Felgenhauer, Stefanie Reiter, Stephan Ludwig, Stefan Pöhlmann, Arora Prerna, Markus Hoffmann, Lars Pelz, Udo Reichl, Sabine Gärtner
Publikováno v:
bioRxiv
Defective interfering (DI) RNAs arise during influenza virus replication, can be packaged into particles (DIPs) and suppress spread of wildtype (WT) virus. However, the molecular signatures of DI RNAs and the mechanism underlying antiviral activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2210bbad5a04a1ef244f17751d2eb7ad
https://doi.org/10.1101/2021.09.20.461172
https://doi.org/10.1101/2021.09.20.461172