Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Lars P. Ryder"'
Autor:
Niels Jacobsen, Tina Frisch, Niels Keiding, Carsten Heilmann, Henrik Sengeløv, Hans O. Madsen, Ebbe Dickmeiss, Lars P. Ryder
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 975-979 (2022)
Abstract The effect of higher FOXP3 mRNA expression by recipient pre‐transplant CD4+ T cells on leukaemia relapse was analysed in a series of 106 patients who received allogeneic haematopoietic stem cell transplantation after myeloablative conditio
Externí odkaz:
https://doaj.org/article/db1f8f4d572b45d4897a0837724b082f
Autor:
Katrine Kielsen, Christian Enevold, Carsten Heilmann, Henrik Sengeløv, Anders Elm Pedersen, Lars P. Ryder, Klaus Müller
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The efficacy of allogeneic hematopoietic stem cell transplantation (HSCT) is challenged by acute and chronic graft-versus-host disease (aGVHD and cGVHD) and viral infections due to long-lasting immunodeficiency. Interleukin-7 (IL-7) is a cytokine ess
Externí odkaz:
https://doaj.org/article/85f0b188fc5241f784542ca1ecdaac3a
Publikováno v:
BioTechniques, Vol 38, Iss 4, Pp 605-610 (2005)
Locked nucleic acid (LNA®) is a modified DNA with increased binding affinity for complementary DNA sequences. Our strategy was to use this property of LNA to inhibit undesired PCR amplification (e.g., from contaminating genomic DNA) in a cDNA-based
Externí odkaz:
https://doaj.org/article/31993f7811744221bc5f99a6b216c37c
Autor:
Nina F. Øbro, Lars P. Ryder, Hans O. Madsen, Mette K. Andersen, Birgitte Lausen, Henrik Hasle, Kjeld Schmiegelow, Hanne V. Marquart
Publikováno v:
Haematologica, Vol 97, Iss 1 (2012)
Reduction in minimal residual disease, measured by real-time quantitative PCR or flow cytometry, predicts prognosis in childhood B-cell precursor acute lymphoblastic leukemia. We explored whether cells reported as minimal residual disease by flow cyt
Externí odkaz:
https://doaj.org/article/9e969df292fa429f8a51d1f92167da47
Autor:
Lia Minculescu, Henrik Sengelov, Hanne Vibeke Marquart, Lars Peter Ryder, Anne Fischer-Nielsen, Eva Haastrup
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Allogeneic hematopoietic stem cell transplantation (HSCT) is a potential cure for patients with hematological malignancies but substantial risks of recurrence of the malignant disease remain. TCR γδ and NK cells are perceived as potent innate effec
Externí odkaz:
https://doaj.org/article/b63188241bb3411d99ede295c678fff5
Autor:
Lia Minculescu, Anne Fischer-Nielsen, Eva Haastrup, Lars Peter Ryder, Niels Smedegaard Andersen, Ida Schjoedt, Lone Smidstrup Friis, Brian Thomas Kornblit, Søren Lykke Petersen, Henrik Sengelov, Hanne Vibeke Marquart
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Mature immunocompetent cells from the stem cell graft as well as early robust immune reconstitution are essential for the graft-vs. -tumor (GVT) effect to eliminate residual malignant cells after allogeneic hematopoietic stem cell transplantation (HS
Externí odkaz:
https://doaj.org/article/f35fe4bc13244fdfbb64076efd61d0ef
Autor:
Vibe Ballegaard, Karin Kaereby Pedersen, Peter Brændstrup, Nikolai Kirkby, Anette Stryhn, Lars P Ryder, Jan Gerstoft, Susanne Dam Nielsen
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226182 (2020)
People living with HIV (PLHIV) are at increased risk for cardiovascular disease (CVD), and immunity against cytomegalovirus (CMV) may be a contributing factor. We hypothesized that enhanced T-cell responses against CMV and CMV-IgG antibody-levels are
Externí odkaz:
https://doaj.org/article/59861f4b0fd94ec9874360e88cf46358
Autor:
Niels Keiding, Ebbe Dickmeiss, Niels Jacobsen, Tina Frisch, Hans O. Madsen, Henrik Sengeløv, Hanne Vibeke Marquart, Carsten Heilmann, Lars P. Ryder, Claus Christiansen, Mette K. Andersen
Publikováno v:
European Journal of Haematology
Jacobsen, N, Frisch, T, Keiding, N, Heilmann, C, Sengeløv, H, Madsen, H O, Marquart, H, Dickmeiss, E, Andersen, M K, Christiansen, C B & Ryder, L P 2021, ' High pre-harvest donor Foxp3 mRNA level predicts late relapse of acute lymphoblastic leukaemia after haematopoietic stem cell transplantation ', European Journal of Haematology, vol. 106, no. 5, pp. 643-653 . https://doi.org/10.1111/ejh.13591
Jacobsen, N, Frisch, T, Keiding, N, Heilmann, C, Sengeløv, H, Madsen, H O, Marquart, H, Dickmeiss, E, Andersen, M K, Christiansen, C B & Ryder, L P 2021, ' High pre-harvest donor Foxp3 mRNA level predicts late relapse of acute lymphoblastic leukaemia after haematopoietic stem cell transplantation ', European Journal of Haematology, vol. 106, no. 5, pp. 643-653 . https://doi.org/10.1111/ejh.13591
OBJECTIVES: The curative effect of allogeneic haematopoietic stem cell transplantation (HSCT) for acute leukaemia is due in part to the donor T cell-mediated graft-versus-leukaemia immune reaction (GvL). Several studies have suggested that donor CD25
Autor:
Klaus Müller, Anders Juul, Henrik Sengeløv, Katrine Kielsen, Lars P. Ryder, Sarah Weischendorff, Claus Henrik Nielsen
Publikováno v:
Weischendorff, S, Sengeløv, H, Juul, A, Nielsen, C H, Ryder, L P, Kielsen, K & Müller, K 2022, ' Insulin-like growth factor-1 and insulin-like growth factor binding protein-3 : impact on early haematopoietic reconstitution following allogeneic haematopoietic stem cell transplantation ', European Journal of Haematology, vol. 108, no. 3, pp. 190-198 . https://doi.org/10.1111/ejh.13724
Objectives: The aim of the study was to investigate whether high endogenous levels of insulin-like growth factor-1 (IGF-1) and its binding protein-3 (IGFBP-3) were related to a faster reconstitution of different blood cell populations in the early ph
Autor:
Lilian Kolte, Benny Dahl, Peter Garred, Lars P. Ryder, Michala Kehrer, Maria Krogstrup, Hanne Vibeke Marquart, Åse Bengård Andersen, Ida E. Gjørup, Susanne Dam Nielsen, Ulrik B. Dragsted, Anna K. Haugaard
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Haugaard, A K, Marquart, H V, Kolte, L, Ryder, L P, Kehrer, M, Krogstrup, M, Dragsted, U B, Dahl, B, Gjørup, I E, Andersen, Å B, Garred, P & Nielsen, S D 2018, ' Quantitative B-lymphocyte deficiency and increased TCRγδ T-lymphocytes in acute infectious spondylodiscitis ', Scientific Reports, vol. 8, 15174 . https://doi.org/10.1038/s41598-018-33318-w
Scientific Reports
Haugaard, A K, Marquart, H V, Kolte, L, Ryder, L P, Kehrer, M, Krogstrup, M, Dragsted, U B, Dahl, B, Gjørup, I E, Andersen, Å B, Garred, P & Nielsen, S D 2018, ' Quantitative B-lymphocyte deficiency and increased TCRγδ T-lymphocytes in acute infectious spondylodiscitis ', Scientific Reports, vol. 8, 15174 . https://doi.org/10.1038/s41598-018-33318-w
Acute infectious spondylodiscitis (AIS) is a serious infection of the spine with rising incidence and a mortality of 3–6%. The role of the immune system in AIS is largely unknown. We performed extensive B and T-lymphocyte phenotyping in patients wi