Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Lars P Erwig"'
Autor:
Mohammed Haider, Ivy M Dambuza, Patawee Asamaphan, Mark Stappers, Delyth Reid, Sho Yamasaki, Gordon D Brown, Neil A R Gow, Lars P Erwig
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220867 (2019)
Phagocytosis is a receptor-mediated process critical to innate immune clearance of pathogens. It proceeds in a regulated sequence of stages: (a) migration of phagocytes towards pathogens, (b) recognition of PAMPs and binding through PRRs, (c) engulfm
Externí odkaz:
https://doaj.org/article/75cdbb4d019d4cd7b8d1cd3b3de8f628
Autor:
Alison M Day, Deborah A Smith, Mélanie A C Ikeh, Mohammed Haider, Carmen M Herrero-de-Dios, Alistair J P Brown, Brian A Morgan, Lars P Erwig, Donna M MacCallum, Janet Quinn
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006131 (2017)
The Ypd1 phosphorelay protein is a central constituent of fungal two-component signal transduction pathways. Inhibition of Ypd1 in Saccharomyces cerevisiae and Cryptococcus neoformans is lethal due to the sustained activation of the 'p38-related' Hog
Externí odkaz:
https://doaj.org/article/8363b7374d17493281fa75d5ffc25161
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101999 (2014)
Fusarium oxysporum is an important plant pathogen and an opportunistic pathogen of humans. Here we investigated phagocytosis of F. oxysporum by J774.1 murine cell line macrophages using live cell video microscopy. Macrophages avidly migrated towards
Externí odkaz:
https://doaj.org/article/9a262df10f57460191ad73052e713ebb
Autor:
Qinxi Ma, Arnab Pradhan, Ian Leaves, Emer Hickey, Elena Roselletti, Ivy Dambuza, Daniel E. Larcombe, Leandro Jose de Assis, Duncan Wilson, Lars P. Erwig, Mihai G. Netea, Delma S. Childers, Gordon D. Brown, Neil A.R. Gow, Alistair J.P. Brown
Publikováno v:
The Cell Surface, Vol 11, Iss , Pp 100128- (2024)
Host recognition of the pathogen-associated molecular pattern (PAMP), β-1,3-glucan, plays a major role in antifungal immunity. β-1,3-glucan is an essential component of the inner cell wall of the opportunistic pathogen Candida albicans. Most β-1,3
Externí odkaz:
https://doaj.org/article/246a9682c09641f7a0a0fda1cc487324
Autor:
Gabriela M. Avelar, Arnab Pradhan, Qinxi Ma, Emer Hickey, Ian Leaves, Corin Liddle, Alejandra V. Rodriguez Rondon, Ann-Kristin Kaune, Sophie Shaw, Corinne Maufrais, Natacha Sertour, Judith M. Bain, Daniel E. Larcombe, Leandro J. de Assis, Mihai G. Netea, Carol A. Munro, Delma S. Childers, Lars P. Erwig, Gordon D. Brown, Neil A. R. Gow, Marie-Elisabeth Bougnoux, Christophe d'Enfert, Alistair J. P. Brown
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Microbial species capable of co-existing with healthy individuals, such as the commensal fungus Candida albicans, exploit multifarious strategies to evade our immune defenses. These strategies include the masking of immunoinflammatory pathog
Externí odkaz:
https://doaj.org/article/a315d65d8db7474e9c59617b6af6132d
Autor:
María Fernanda Alonso, Judith M. Bain, Fiona M. Rudkin, Lars P. Erwig, Alistair J.P. Brown, Neil A.R. Gow
Publikováno v:
The Cell Surface, Vol 9, Iss , Pp 100106- (2023)
Externí odkaz:
https://doaj.org/article/30426ef88bc143d598db4acfd6573381
Autor:
Leandro José de Assis, Judith M. Bain, Corin Liddle, Ian Leaves, Christian Hacker, Roberta Peres da Silva, Raif Yuecel, Attila Bebes, David Stead, Delma S. Childers, Arnab Pradhan, Kevin Mackenzie, Katherine Lagree, Daniel E. Larcombe, Qinxi Ma, Gabriela Mol Avelar, Mihai G. Netea, Lars P. Erwig, Aaron P. Mitchell, Gordon D. Brown, Neil A. R. Gow, Alistair J. P. Brown
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Candida albicans exists as a commensal of mucosal surfaces and the gastrointestinal tract without causing pathology. However, this fungus is also a common cause of mucosal and systemic infections when antifungal immune defenses become compro
Externí odkaz:
https://doaj.org/article/7eee21d07077458d862a678b6efa049c
Publikováno v:
Autoimmunity, Vol 53, Iss 3, Pp 148-155 (2020)
Neutrophils, monocytes and the endothelium are critical to ANCA-associated vasculitis (AAV) pathogenesis. This study aimed to develop a 4-dimensional (4D) live-cell imaging system that would enable investigation of spatial and temporal dynamics of th
Externí odkaz:
https://doaj.org/article/8afbe4f709564471b0feaa82daefd1d9
Autor:
Gabriela M, Avelar, Ivy M, Dambuza, Liviana, Ricci, Raif, Yuecel, Kevin, Mackenzie, Delma S, Childers, Judith M, Bain, Arnab, Pradhan, Daniel E, Larcombe, Mihai G, Netea, Lars P, Erwig, Gordon D, Brown, Sylvia H, Duncan, Neil A R, Gow, Alan W, Walker, Alistair J P, Brown
Publikováno v:
Cell surface (Amsterdam, Netherlands). 8
The immunogenicity of
Autor:
María Fernanda Alonso, Judith M. Bain, Fiona M. Rudkin, Lars P. Erwig, Alistair J.P. Brown, Neil A.R. Gow
Publikováno v:
Cell surface (Amsterdam, Netherlands). 8
Phagocytosis is an essential component of our immune defence against fungal pathogens. Differences in the dynamics of phagocyte migration, recognition, uptake and phagolysosome maturation are dependent on the characteristics of the fungal cargo, and