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Autor:
Kavish A.V. Kohabir, Lars O. Nooi, Arjen Brink, Ruud H. Brakenhoff, Erik A. Sistermans, Rob M.F. Wolthuis
Publikováno v:
Kohabir, KAV, Nooi, L, Brink, A, Brakenhoff, RH, Sistermans, EA & Wolthuis, RMF 2023, ' In Vitro CRISPR-Cas12a-Based Detection of Cancer-Associated TP53 Hotspot Mutations Beyond the crRNA Seed Region ', The CRISPR Journal, vol. 6, no. 2, pp. 127-139 . https://doi.org/10.1089/crispr.2022.0077
The CRISPR Journal, 6(2), 127-139. Mary Ann Liebert Inc.
The CRISPR Journal, 6(2), 127-139. Mary Ann Liebert Inc.
Cost-effective and time-efficient detection of oncogenic mutations supports improved presymptomatic cancer diagnostics and post-treatment disease monitoring. Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas12a is an RNA-guided e