Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Lars O. Hansson"'
Autor:
Townsend, Patricia K.
Publikováno v:
Health Transition Review, 1996 Oct 01. 6(2), 233-234.
Externí odkaz:
https://www.jstor.org/stable/40652223
Autor:
Atosa Nejatian, Therese Djärv, Jonas Höijer, Kai M. Eggers, Lars O. Hansson, Per Svensson, Åsa Omstedt
Publikováno v:
Journal of the American College of Cardiology. 69(21)
Background Most patients with chest pain are discharged from the emergency department (ED) with the diagnosis “unspecified chest pain.” It is unknown if evaluation with a high-sensitivity troponin T (hsTnT) assay affects prognosis in this large p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a974dc00aa1c8ed4486affce9e56c9d6
https://pubmed.ncbi.nlm.nih.gov/28545636
https://pubmed.ncbi.nlm.nih.gov/28545636
Publikováno v:
Scopus-Elsevier
Two human Mu class glutathione transferases, hGST M1-1 and hGST M2-2, with high sequence identity (84%) exhibit a 100-fold difference in activities with the substrates aminochrome, 2-cyano-1,3-dimethyl-1-nitrosoguanidine (cyanoDMNG), and 1,2-dichloro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a363360158b3db367c47109808b2406
https://doi.org/10.1110/ps.8.12.2742
https://doi.org/10.1110/ps.8.12.2742
Publikováno v:
Journal of Biological Chemistry. 278:24108-24112
Kinetic instability of p53 core domain mutants. Implications for rescue by small molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae8c00d71f195587ac8b8132b2639fef
https://doi.org/10.1074/jbc.m302458200
https://doi.org/10.1074/jbc.m302458200
Autor:
Mark R. Proctor, Thomas M Rippin, Lars O. Hansson, Penka V. Nikolova, Assaf Friedler, Alan R. Fersht, Dmitry B. Veprintsev, Stefan M.V. Freund, Stefan G.D. Rüdiger
Publikováno v:
Proceedings of the National Academy of Sciences. 99:937-942
Conformationally compromised oncogenic mutants of the tumor suppressor protein p53 can, in principle, be rescued by small molecules that bind the native, but not the denatured state. We describe a strategy for the rational search for such molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122628f7bea9f44c4f0a7c1f8a7b24c3
https://doi.org/10.1073/pnas.241629998
https://doi.org/10.1073/pnas.241629998
Publikováno v:
Journal of Molecular Biology. 287:265-276
A library of variant enzymes was created by combined shuffling of the DNA encoding the human Mu class glutathione transferases GST M1-1 and GST M2-2. The parental GSTs are 84% sequence identical at the protein level, but their specific activities wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8206fd06fe6fdc28d75039bd69a5872a
https://doi.org/10.1006/jmbi.1999.2607
https://doi.org/10.1006/jmbi.1999.2607
Publikováno v:
Journal of Medicinal Chemistry. 38:3121-3131
The quantitative structure-activity relationship between physicochemical properties and effects on dopamine (DA) synthesis and release in the rat brain, in a series of meta-substituted (S)-phenylpiperidines, has been investigated by means of partial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9751ece31e4967935dca34d93debd2a
https://doi.org/10.1021/jm00016a015
https://doi.org/10.1021/jm00016a015
Autor:
Robert Louis Hoffman, Stjernlöf P, Lars O. Hansson, Håkan Wikström, Arvid Carlsson, Ennis, Kjell A. Svensson, Nabil B. Ghazal, M. W. Smith, S. Sundell
Publikováno v:
Journal of Medicinal Chemistry. 38:2202-2216
A series of 1-, 3-, and 4-substituted analogs to the potent 5-HT1A against 8-(dipropylamino)-6,7,8,9-tetrahydro-3H-benz[e]indole-1-carbaldehyde (5) were prepared and tested in vitro at 5-HT1A, 5-HT1D alpha, 5-HT1D beta, D2, and D3 receptors and in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b768767d7aa42aaa34ab860911f16f73
https://doi.org/10.1021/jm00012a021
https://doi.org/10.1021/jm00012a021
Autor:
Arvid Carlsson, M. W. Smith, Kjell A. Svensson, Chiu-Hong Lin, Nicholas Waters, Håkan Wikström, Lars O. Hansson, Clas Sonesson
Publikováno v:
Journal of Medicinal Chemistry. 37:2735-2753
A series of (S)-phenylpiperidines in which the substituents on the aromatic ring and nitrogen have been varied has been prepared. They have been evaluated pharmacologically to explore the importance of these substituents for the interaction with cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7035f690f32429555d4288e1a43e98
https://doi.org/10.1021/jm00043a013
https://doi.org/10.1021/jm00043a013
Autor:
Lars O. Hansson, Michael D. Ennis, P. Stjernloef, Arvid Carlsson, N. B. Ghazal, M. W. Smith, S. Sundell, Kjell A. Svensson, H. Wikstroem, Robert Louis Hoffman
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f8f719e697c01ab1184a3abf87c6c42
https://doi.org/10.1002/chin.199542132
https://doi.org/10.1002/chin.199542132