Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lars N G, Nilsson"'
Autor:
María Pagnon de la Vega, Stina Syvänen, Vilmantas Giedraitis, Monique Hooley, Evangelos Konstantinidis, Silvio R. Meier, Johanna Rokka, Jonas Eriksson, Ximena Aguilar, Tara L. Spires-Jones, Lars Lannfelt, Lars N. G. Nilsson, Anna Erlandsson, Greta Hultqvist, Martin Ingelsson, Dag Sehlin
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Deposition of amyloid beta (Aβ) into plaques is a major hallmark of Alzheimer’s disease (AD). Different amyloid precursor protein (APP) mutations cause early-onset AD by altering the production or aggregation properties of Aβ. We recentl
Externí odkaz:
https://doaj.org/article/e1e6c9096c0f4e3e9f714a2564198215
Autor:
Kaja Nordengen, Bjørn-Eivind Kirsebom, Kristi Henjum, Per Selnes, Berglind Gísladóttir, Marianne Wettergreen, Silje Bøen Torsetnes, Gøril Rolfseng Grøntvedt, Knut K. Waterloo, Dag Aarsland, Lars N. G. Nilsson, Tormod Fladby
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Neuronal and glial cell interaction is essential for synaptic homeostasis and may be affected in Alzheimer’s disease (AD). We measured cerebrospinal fluid (CSF) neuronal and glia markers along the AD continuum, to reveal putativ
Externí odkaz:
https://doaj.org/article/fd63657c79bf49b3a917e28d4196c15b
Autor:
Kristi Henjum, Else Quist-Paulsen, Henrik Zetterberg, Kaj Blennow, Lars N. G. Nilsson, Leiv Otto Watne
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Delirium and dementia share symptoms of cognitive dysfunctions, and mechanisms of neuroinflammation appear involved in both conditions. Triggering receptor expressed on myeloid cells 2 (TREM2) is linked to dementia and neurodegene
Externí odkaz:
https://doaj.org/article/6fe10ad4cfe64a93b3cbbfa0132e684f
Autor:
Mara Zielinski, Fernanda S. Peralta Reyes, Lothar Gremer, Sarah Schemmert, Benedikt Frieg, Antje Willuweit, Lili Donner, Margitta Elvers, Lars N. G. Nilsson, Stina Syvänen, Dag Sehlin, Martin Ingelsson, Dieter Willbold, Gunnar F. Schröder
The development of novel drugs for Alzheimer’s disease has proven difficult, with a high failure rate in clinical trials. Typically, transgenic mice displaying amyloid-β peptide brain pathology are used to develop therapeutic options and to test t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fea5213246e1743a0e644ac7a1b0521
https://doi.org/10.1101/2023.03.30.534981
https://doi.org/10.1101/2023.03.30.534981
Autor:
Knut Sindre, Åbjørsbråten, Gry H E Syverstad, Skaaraas, Céline, Cunen, Daniel M, Bjørnstad, Kristin M Gullestad, Binder, Laura, Bojarskaite, Vidar, Jensen, Lars N G, Nilsson, Shreyas B, Rao, Wannan, Tang, Gudmund Horn, Hermansen, Erlend A, Nagelhus, Ole Petter, Ottersen, Reidun, Torp, Rune, Enger
Publikováno v:
eLife. 11
Increased astrocytic CaNeurodegenerative conditions such as Parkinson’s or Alzheimer’s disease are characterized by neurons dying and being damaged. Yet neurons are only one type of brain actors; astrocytes, for example, are star-shaped ‘compan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00c2856d8105ba0c94962eab41bf25a7
https://pubmed.ncbi.nlm.nih.gov/35833623
https://pubmed.ncbi.nlm.nih.gov/35833623
Autor:
Syed Nuruddin, Gry Helen Enger Syverstad, Sveinung Lillehaug, Trygve B Leergaard, Lars N G Nilsson, Erik Ropstad, Anette Krogenæs, Ira Ronit Hebold Haraldsen, Reidun Torp
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103607 (2014)
Research on Alzheimer's disease (AD) has indicated an association between hormones of the hypothalamic-pituitary-gonadal (HPG) axis and cognitive senescence, indicating that post meno-/andropausal changes in HPG axis hormones are implicated in the ne
Externí odkaz:
https://doaj.org/article/b462630ad3a74734ba68abc828da7dd3
Autor:
María, Pagnon de la Vega, Vilmantas, Giedraitis, Wojciech, Michno, Lena, Kilander, Gökhan, Güner, Mara, Zielinski, Malin, Löwenmark, RoseMarie, Brundin, Torsten, Danfors, Linda, Söderberg, Irina, Alafuzoff, Lars N G, Nilsson, Anna, Erlandsson, Dieter, Willbold, Stephan A, Müller, Gunnar F, Schröder, Jörg, Hanrieder, Stefan F, Lichtenthaler, Lars, Lannfelt, Dag, Sehlin, Martin, Ingelsson
Publikováno v:
Science translational medicine. 13(606)
Point mutations in the amyloid precursor protein gene (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc4960a61345b24b56f0659009458f07
https://pubmed.ncbi.nlm.nih.gov/35020408
https://pubmed.ncbi.nlm.nih.gov/35020408
Autor:
Elin S. Blom, Yijing Wang, Lena Skoglund, Anita C. Hansson, Massimo Ubaldi, Anbarasu Lourdusamy, Wolfgang H. Sommer, Matthew Mielke, Bradley T. Hyman, Markus Heilig, Lars Lannfelt, Lars N. G. Nilsson, Martin Ingelsson
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2011 (2011)
Several components in the Wnt pathway, including β-catenin and glycogen synthase kinase 3 beta, have been implied in AD pathogenesis. Here, mRNA brain levels from five-month-old tg-ArcSwe and nontransgenic mice were compared using Affymetrix microar
Externí odkaz:
https://doaj.org/article/d9bbda63616845afba269724ed317840
Publikováno v:
Nutrition reviews. 68
The identification of disease-causing mutations in Alzheimer's disease has contributed greatly to the understanding of the pathogenesis of this disease. The amyloid-β (Aβ) peptide has come into focus and is believed to be central to the pathogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc26d5aacf7f168bce7e8de03f009e0f
https://pubmed.ncbi.nlm.nih.gov/21091946
https://pubmed.ncbi.nlm.nih.gov/21091946
Autor:
Martin, Ingelsson, Hans, Basun, Frida Ekholm, Pettersson, Lena, Kilander, Lars N G, Nilsson, Lars, Lannfelt
Publikováno v:
Lakartidningen. 106(20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::982bef0855688926d1a88184a115df7d
https://pubmed.ncbi.nlm.nih.gov/19585838
https://pubmed.ncbi.nlm.nih.gov/19585838