Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Lars Martin Jakt"'
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Spliceosomal introns are parts of primary transcripts that are removed by RNA splicing. Although introns apparently do not contribute to the function of the mature transcript, in vertebrates they comprise the majority of the trans
Externí odkaz:
https://doaj.org/article/3bf8273b850844129856ffcdd286a93d
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective Analyze key features of the anglerfish Lophius piscatorius mitochondrial transcriptome based on high-throughput total RNA sequencing. Results We determined the complete mitochondrial DNA and corresponding transcriptome sequences of
Externí odkaz:
https://doaj.org/article/d40ec6ba02794955850ea184f91583f8
Autor:
Yuhki Nakatake, Shigeru B.H. Ko, Alexei A. Sharov, Shunichi Wakabayashi, Miyako Murakami, Miki Sakota, Nana Chikazawa, Chiaki Ookura, Saeko Sato, Noriko Ito, Madoka Ishikawa-Hirayama, Siu Shan Mak, Lars Martin Jakt, Tomoo Ueno, Ken Hiratsuka, Misako Matsushita, Sravan Kumar Goparaju, Tomohiko Akiyama, Kei-ichiro Ishiguro, Mayumi Oda, Norio Gouda, Akihiro Umezawa, Hidenori Akutsu, Kunihiro Nishimura, Ryo Matoba, Osamu Ohara, Minoru S.H. Ko
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: Transcription factors (TFs) play a pivotal role in determining cell states, yet our understanding of the causative relationship between TFs and cell states is limited. Here, we systematically examine the state changes of human pluripotent em
Externí odkaz:
https://doaj.org/article/5e01196c36404cffa69b4492e2cf07ae
Autor:
Tor Erik Jørgensen, Bård Ove Karlsen, Åse Emblem, Ragna Breines, Morten Andreassen, Trine B. Rounge, Alexander J. Nederbragt, Kjetill S. Jakobsen, Marianne Nymark, Anita Ursvik, Dag H. Coucheron, Lars Martin Jakt, Jarle T. Nordeide, Truls Moum, Steinar D. Johansen
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract Objective The objective of this study was to analyse intraspecific sequence variation of Atlantic cod mitochondrial DNA, based on a comprehensive collection of completely sequenced mitochondrial genomes. Results We determined the complete mi
Externí odkaz:
https://doaj.org/article/248be8e4c3cd46b4a062c32405825972
Autor:
Anne-Catrin Adam, Kai Kristoffer Lie, Paul Whatmore, Lars Martin Jakt, Mari Moren, Kaja Helvik Skjærven
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220934 (2019)
Diet has been shown to influence epigenetic key players, such as DNA methylation, which can regulate the gene expression potential in both parents and offspring. Diets enriched in omega-6 and deficient in omega-3 PUFAs (low dietary omega-3/omega-6 PU
Externí odkaz:
https://doaj.org/article/ef9ee70f7e09449a838acf850a0516a0
Autor:
Silvia Muñoz Descalzo, Pau Rué, Fernando Faunes, Penelope Hayward, Lars Martin Jakt, Tina Balayo, Jordi Garcia‐Ojalvo, Alfonso Martinez Arias
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-10 (2013)
Abstract Pluripotency in embryonic stem cells is maintained through the activity of a small set of transcription factors centred around Oct4 and Nanog, which control the expression of ‘self‐renewal’ and ‘differentiation’ genes. Here, we com
Externí odkaz:
https://doaj.org/article/2a0c6b4a9c574958bdff328aed136b25
Autor:
Masaaki Oda, Yuichi Kumaki, Masaki Shigeta, Lars Martin Jakt, Chisa Matsuoka, Akiko Yamagiwa, Hitoshi Niwa, Masaki Okano
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003574 (2013)
DNA methylation changes dynamically during development and is essential for embryogenesis in mammals. However, how DNA methylation affects developmental gene expression and cell differentiation remains elusive. During embryogenesis, many key transcri
Externí odkaz:
https://doaj.org/article/7f58336051194d5eb202a456986f5644
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71099 (2013)
Treatment with the demethylating drugs 5-azacytidine (AZA) and decitabine (DAC) is now recognised as an effective therapy for patients with Myelodysplastic Syndromes (MDS), a range of disorders arising in clones of hematopoietic progenitor cells. A v
Externí odkaz:
https://doaj.org/article/3e3131e8bfdc4c6c8e3ae5e919c54132
Autor:
Sentaro Kusuhara, Yoko Fukushima, Shigetomo Fukuhara, Lars Martin Jakt, Mitsuhiro Okada, Yuri Shimizu, Masayuki Hata, Kohji Nishida, Akira Negi, Masanori Hirashima, Naoki Mochizuki, Shin-Ichi Nishikawa, Akiyoshi Uemura
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45858 (2012)
BACKGROUND: Drugs inhibiting vascular endothelial growth factor (VEGF) signaling are globally administered to suppress deregulated angiogenesis in a variety of eye diseases. However, anti-VEGF therapy potentially affects the normal functions of retin
Externí odkaz:
https://doaj.org/article/8376c912cca04be2ab760e0d078e03b0
Publikováno v:
BMC Genomics
Background Spliceosomal introns are parts of primary transcripts that are removed by RNA splicing. Although introns apparently do not contribute to the function of the mature transcript, in vertebrates they comprise the majority of the transcribed re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bfb0c4a719bea4069657fda79ca79a
https://doi.org/10.1186/s12864-022-08760-w
https://doi.org/10.1186/s12864-022-08760-w
