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Akademický článek

Changes in drug load during lacosamide combination therapy: A noninterventional, observational study in German and Austrian clinical practice

Autor: Fritjof Reinhardt, Yvonne G. Weber, Thomas Mayer, Gerhard Luef, Lars Joeres, Frank Tennigkeit, Peter Dedeken, Marc De Backer, Scarlett Hellot, Thomas Lauterbach, Tanja Webers, Stephan Arnold

Publikováno v: Epilepsia Open, Vol 4, Iss 3, Pp 409-419 (2019)

Abstract Introduction Effects of antiepileptic drug (AED) load changes in patients with focal seizures have not been well evaluated. Methods SP1065 (NCT01673282) was a noninterventional, prospective, observational study conducted in a clinical practi

Externí odkaz: https://doaj.org/article/c19e3571bedb418a83c96b0c9099851e

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Relative importance of clinical outcomes and safety risks of antiseizure medication monotherapy for patients and physicians: Discrete choice experiment eliciting preferences in real‐world study 'VOTE'

Autor: Felix Rosenow, Yaroslav Winter, Iryna Leunikava, Marcus Brunnert, Lars Joeres, Jessie Sutphin, Marco Boeri, Jasmine Smith, Flavio Villani, Christian Brandt

Publikováno v: Rosenow, F, Winter, Y, Leunikava, I, Brunnert, M, Joeres, L, Sutphin, J, Boeri, M, Smith, J, Villani, F & Brandt, C 2022, ' Relative importance of clinical outcomes and safety risks of antiseizure medication monotherapy for patients and physicians: Discrete choice experiment eliciting preferences in real-world study "VOTE" ', Epilepsia, vol. 63, no. 2, pp. 451-462 . https://doi.org/10.1111/epi.17137

Objective: This study was undertaken to elicit patients' preferences for attributes characterizing antiseizure medication (ASM) monotherapy options before treatment consultation, and to explore the trade‐offs patients consider between treatment eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c625043d263924bdadf5244e8b2046
https://doi.org/10.1111/epi.17137

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Treatment Patterns and Resource Utilization of Pregnant Women with Inflammatory Rheumatic Diseases or Psoriasis in Germany: A Claims Database Analysis

Autor: Ursula Marschall, Ingrid Schubert, Rebecca Fischer-Betz, Lars Joeres, Wojciech Dombrowsky, Tanja Heidbrede, Katja Blaschke

Publikováno v: Rheumatology and Therapy

Background Uncontrolled inflammatory disease activity can impact pregnancy outcomes and the health of the mother and child. This retrospective claims database analysis assessed treatment patterns before, during, and after pregnancy among women with i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939063db7b5ff92a00323aa903d7ab49
https://doi.org/10.1007/s40744-021-00347-3

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Osteoporotic fractures and subsequent fractures: imminent fracture risk from an analysis of German real-world claims data

Autor: P Gille, Bernd Schweikert, Lars Joeres, Luis Möckel, Claus-C. Glüer, E Toth, Edda Kloppmann, Peyman Hadji

Publikováno v: Archives of Gynecology and Obstetrics

Purpose In osteoporosis, prior fracture is a strong predictor of subsequent fracture. This study aimed to assess the imminent risk of subsequent fracture following an initial fracture in osteoporosis patients in Germany, and to identify clinical and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2fe56cc47af8b419164f27fa8c3259
https://doi.org/10.1007/s00404-021-06123-6

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Poststroke epilepsy incidence, risk factors and treatment: German claims analysis

Autor: Fränce Hardtstock, Nadia Foskett, Patrick Gille, Lars Joeres, Manuela Molzan, Jessica Claire Wilson, Thomas Wilke, Martin Holtkamp

Publikováno v: Acta Neurologica Scandinavica

Objectives To describe incidence, risk factors, and treatment of poststroke epilepsy (PSE) in Germany based on claims data. Methods Retrospective analysis of claims data from a German public sickness fund (AOK PLUS). Patients with acute stroke hospit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb10e426637633700116b4e87d98a2b
https://doi.org/10.1111/ane.13403

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Effectiveness and tolerability of lacosamide as add-on therapy in patients with brain tumor–related epilepsy

Autor: Iryna Leunikava, Roberta Rudà, Marc De Backer, Jaap C. Reijneveld, Marta Maschio, Jane Chan, Robin Grant, Scarlett Hellot, Lars Joeres, Martin Glas, Caroline Houillier

Publikováno v: Epilepsia
Epilepsia, 61(4), 647-656. Wiley-Blackwell
Rudà, R, Houillier, C, Maschio, M, Reijneveld, J C, Hellot, S, De Backer, M, Chan, J, Joeres, L, Leunikava, I, Glas, M & Grant, R 2020, ' Effectiveness and tolerability of lacosamide as add-on therapy in patients with brain tumor–related epilepsy : Results from a prospective, noninterventional study in European clinical practice (VIBES) ', Epilepsia, vol. 61, no. 4, pp. 647-656 . https://doi.org/10.1111/epi.16486

Objective: To evaluate the effectiveness and tolerability of lacosamide added to one or two antiepileptic drugs (AEDs) in the treatment of patients with brain tumor–related epilepsy (BTRE), and to evaluate patients’ global impression of change an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6486c7f806cbf5c44857a6c2c3a505
https://doi.org/10.1111/epi.16486

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Estimated epidemiology of osteoporosis diagnoses and osteoporosis-related high fracture risk in Germany: a German claims data analysis

Autor: Peyman Hadji, Fränce Hardtstock, Thomas Wilke, Lars Joeres, Emese Toth, Luis Möckel, Patrick Gille

Publikováno v: Archives of osteoporosis. 15(1)

In 2016, an estimated 143,967 female and 25,315 male patients had a diagnosis of osteoporosis, accounting for 4.44% of the German population. Due to an aging population, an increase in the number of osteoporosis patients and osteoporotic fractures ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbf56a3d97e1bd380373e5eac1cc27a
https://pubmed.ncbi.nlm.nih.gov/32783079

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Significant association between systolic and diastolic blood pressure elevations and periodic limb movements in patients with idiopathic restless legs syndrome

Autor: Frank Grieger, Karl Kesper, Axel Bauer, Claudia Trenkwalder, Lars Joeres, Werner Cassel, Erwin Schollmayer

Publikováno v: Sleep Medicine. 17:109-120

Objective A new and unique methodology was developed to evaluate the association between periodic limb movements (PLMs) and nocturnal blood pressure (BP) excursions in patients with restless legs syndrome (RLS). Methods All data were collected at bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489a74eeb2487e00e93b97eae1e950e4
https://doi.org/10.1016/j.sleep.2014.12.019

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OS10.2 Effectiveness and tolerability of lacosamide as add-on therapy in patients with brain tumor-related epilepsy: results from a prospective, non-interventional study in European clinical practice

Autor: Lars Joeres, M. De Backer, Robin Grant, J. Chan, Roberta Rudà, Scarlett Hellot, Iryna Leunikava

Publikováno v: Neuro Oncol

BACKGROUND Data on the use of lacosamide (LCM) for the treatment of brain tumor-related epilepsy (BTRE) are limited. The objective of this study was to evaluate the effectiveness and tolerability of LCM added to 1 or 2 antiepileptic drugs (AEDs) in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e7bedc8d047c84f96b53f34452c8ff
https://doi.org/10.1093/neuonc/noz126.068

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