Zobrazeno 1 - 10 of 187 pro vyhledávání: '"Lars H Pinborg"'
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Akademický článek
Ictal and interictal SPECT with 99mTc‐HMPAO in presurgical epilepsy. II: Methodological considerations on hyper‐ and hypoperfusion
Autor: Martin Prener, Veronica Drejer, Morten Ziebell, Per Jensen, Camilla Gøbel Madsen, Svitlana Olsen, Gerda Thomsen, Lars H. Pinborg, Olaf B. Paulson
Publikováno v: Epilepsia Open, Vol 8, Iss 4, Pp 1503-1511 (2023)
Abstract Objective Single‐photon emission computed tomography (SPECT) with the tracer 99mTc‐HMPAO is a method to visualize the cerebral hyperperfusion during an epileptic seizure and thus localize the epileptogenic zone and seizure propagation. S
Externí odkaz: https://doaj.org/article/20cadc0d72f34da6b6a7ae857779953a
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2
Akademický článek
Ictal and interictal SPECT with 99mTc‐HMPAO in presurgical epilepsy. I: Predictive value and methodological considerations
Autor: Martin Prener, Veronica Drejer, Morten Ziebell, Per Jensen, Camilla Gøbel Madsen, Svitlana Olsen, Gerda Thomsen, Lars H. Pinborg, Olaf B. Paulson
Publikováno v: Epilepsia Open, Vol 8, Iss 3, Pp 1064-1074 (2023)
Abstract Objective This retrospective study investigates the predictive value of ictal subtraction single‐photon emission computed tomography (SPECT) co‐registered to magnetic resonance imaging (MRI) (SISCOM) for successful epilepsy surgery. Meth
Externí odkaz: https://doaj.org/article/39293c377c874a759d9665cdb3ec8248
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3
Akademický článek
Deep phenotyping towards precision psychiatry of first-episode depression — the Brain Drugs-Depression cohort
Autor: Kristian Høj Reveles Jensen, Vibeke H. Dam, Melanie Ganz, Patrick MacDonald Fisher, Cheng-Teng Ip, Anjali Sankar, Maja Rou Marstrand-Joergensen, Brice Ozenne, Merete Osler, Brenda W. J. H. Penninx, Lars H. Pinborg, Vibe Gedsø Frokjaer, Gitte Moos Knudsen, Martin Balslev Jørgensen
Publikováno v: BMC Psychiatry, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Major Depressive Disorder (MDD) is a heterogenous brain disorder, with potentially multiple psychosocial and biological disease mechanisms. This is also a plausible explanation for why patients do not respond equally well to treat
Externí odkaz: https://doaj.org/article/5c5e9049498647299c8ad0ed52ae3969
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4
Akademický článek
Accuracy of high-density EEG electrode position measurement using an optical scanner compared with the photogrammetry method
Autor: Orsolya Györfi, Cheng-Teng Ip, Anders Bach Justesen, Maria Louise Gam-Jensen, Connie Rømer, Martin Fabricius, Lars H. Pinborg, Sándor Beniczky
Publikováno v: Clinical Neurophysiology Practice, Vol 7, Iss , Pp 135-138 (2022)
Objective: To determine the feasibility and accuracy of a handheld optical scanner to measure the three-dimensional (3D) EEG electrode coordinates in a high-density array of 256 electrodes. Methods: We compared the optical scanning with a previously
Externí odkaz: https://doaj.org/article/d15932b5684d46bfb4c7d991b0b946b1
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5
Akademický článek
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis
Autor: Ulrich Pfisterer, Viktor Petukhov, Samuel Demharter, Johanna Meichsner, Jonatan J. Thompson, Mykhailo Y. Batiuk, Andrea Asenjo-Martinez, Navneet A. Vasistha, Ashish Thakur, Jens Mikkelsen, Istvan Adorjan, Lars H. Pinborg, Tune H. Pers, Jakob von Engelhardt, Peter V. Kharchenko, Konstantin Khodosevich
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
The pathophysiology of epilepsy is unclear. Here, the authors present single-nuclei transcriptomic profiling of human temporal lobe epilepsy from patients. They identified epilepsy-associated neuronal subtypes, and a panel of dysregulated genes, pred
Externí odkaz: https://doaj.org/article/3e192b5fa2834006a330d7be93363fc6
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6
Akademický článek
Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease
Autor: Claudia Salcedo, Jens V. Andersen, Kasper Tore Vinten, Lars H. Pinborg, Helle S. Waagepetersen, Kristine K. Freude, Blanca I. Aldana
Publikováno v: Frontiers in Aging Neuroscience, Vol 13 (2021)
The branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are important nitrogen donors for synthesis of glutamate, the main excitatory neurotransmitter in the brain. The glutamate carbon skeleton originates from the tricarboxylic acid (
Externí odkaz: https://doaj.org/article/23c5fe2f5f55464ea4295163af65bed6
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7
Akademický článek
A high-resolution in vivo atlas of the human brain's benzodiazepine binding site of GABAA receptors
Autor: Martin Nørgaard, Vincent Beliveau, Melanie Ganz, Claus Svarer, Lars H Pinborg, Sune H Keller, Peter S Jensen, Douglas N. Greve, Gitte M. Knudsen
Publikováno v: NeuroImage, Vol 232, Iss , Pp 117878- (2021)
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the human brain and plays a key role in several brain functions and neuropsychiatric disorders such as anxiety, epilepsy, and depression. For decades, several in vivo and ex vi
Externí odkaz: https://doaj.org/article/d03bbbc3812b4e9abc8fe5b6bdce7aa2
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8
Akademický článek
Striatal Volume Increase After Six Weeks of Selective Dopamine D2/3 Receptor Blockade in First-Episode, Antipsychotic-Naïve Schizophrenia Patients
Autor: Helle G. Andersen, Jayachandra M. Raghava, Claus Svarer, Sanne Wulff, Louise B. Johansen, Patrick K. Antonsen, Mette Ø. Nielsen, Egill Rostrup, Anthony C. Vernon, Lars T. Jensen, Lars H. Pinborg, Birte Y. Glenthøj, Bjørn H. Ebdrup
Publikováno v: Frontiers in Neuroscience, Vol 14 (2020)
Patients with chronic schizophrenia often display enlarged striatal volumes, and antipsychotic drugs may contribute via the dopamine D2/3 receptor (D2/3R) blockade. Separating the effects of disease from medication is challenging due to the lack of a
Externí odkaz: https://doaj.org/article/bf7facf14d5340eca56fdadecd72d8eb
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10
Postprocessing of MRIs Using FreeSurfer in Epilepsy Surgery Patients Provides an Excellent Imaging Marker of Hippocampal Sclerosis but Fails to Separate Subtypes
Autor: Ane G. Kloster, Giske Opheim, Kristin Å. Alfstad, Karen B. Larsen, Pitt Niehusmann, Emil Holm, Philip Fink-Jensen, Eva Løbner Lund, Bo Jespersen, Jugoslav Ivanovic, Guido Rubboli, Camilla G. Madsen, Pål B. Marthinsen, Melanie Ganz, Morten Lossius, Lars H. Pinborg
Publikováno v: Kloster, A G, Opheim, G, Alfstad, K, Larsen, K B, Niehusmann, P, Holm, E, Fink-Jensen, P, Lund, E L, Jespersen, B, Ivanovic, J, Rubboli, G, Madsen, C G, Marthinsen, P B, Ganz, M, Lossius, M & Pinborg, L H 2023, ' Postprocessing of MRIs Using FreeSurfer in Epilepsy Surgery Patients Provides an Excellent Imaging Marker of Hippocampal Sclerosis but Fails to Separate Subtypes ', Acta Neurologica Scandinavica, vol. 2023, 2366355 . https://doi.org/10.1155/2023/2366355
Objective. Histopathological examinations will diminish as minimally invasive epilepsy surgery increasingly replaces open surgery. The objective of this study was to test if visual and computer-aided quantitative analyses of presurgical high-quality
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0953e159ec6d4958473fa746ca488e
https://curis.ku.dk/portal/da/publications/postprocessing-of-mris-using-freesurfer-in-epilepsy-surgery-patients-provides-an-excellent-imaging-marker-of-hippocampal-sclerosis-but-fails-to-separate-subtypes(ad84ecd5-f7ff-42b1-927a-c89e3cf35c81).html
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