Effect of tiotropium and olodaterol on symptoms and patient-reported outcomes in patients with COPD: results from four randomised, double-blind studies

Autor: Gary T. Ferguson, Jill Karpel, Nathan Bennett, Emmanuelle Clerisme-Beaty, Lars Grönke, Florian Voß, Roland Buhl

Publikováno v: npj Primary Care Respiratory Medicine, Vol 27, Iss 1, Pp 1-9 (2017)

Chronic obstructive pulmonary disease: Combined inhaler proves effective Results from four in-depth studies show that a combined inhaler is very effective for treatment of moderate to severe chronic lung disease. Alleviating the symptoms of chronic o

Externí odkaz: https://doaj.org/article/406e40dbb4ce42a9aa38295481bd3e25

β-Blockers in COPD

Autor: Gary T. Ferguson, Florian Voß, Valeria C. Amatto, Roland Buhl, Jim Reid, Lars Grönke, Andrea Koch, François Maltais, Ulrich Bothner, Lorcan McGarvey

Publikováno v: Chest. 153:1315-1325

Background Cardiovascular disease is a frequent comorbidity in patients with COPD. Many physicians, particularly pulmonologists, are reluctant to use β-adrenoceptor blocking agents (β-blockers) in patients with COPD, despite their proven effectiven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39a79e1da8e3196a2c6de23b39e814ef
https://doi.org/10.1016/j.chest.2018.01.008

Study Design of VESUTO®: Efficacy of Tiotropium/Olodaterol on Lung Hyperinflation, Exercise Capacity, and Physical Activity in Japanese Patients with Chronic Obstructive Pulmonary Disease

Autor: Jun Ueki, Masakazu Ichinose, Takashi Motegi, Lars Grönke, Tatsuhiko Anzai, Ayako Takizawa, Kazuto Hirata, Tetsuo Seki, Yoshiaki Minakata

Publikováno v: Advances in Therapy

Introduction The superiority of tiotropium/olodaterol is demonstrated in improvement of lung function, dyspnea, lung hyperinflation, and quality of life compared with either monotherapy in patients with chronic obstructive pulmonary disease (COPD). J

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9d576144ea3df31fd1ef418bf52383
http://europepmc.org/articles/PMC5504218

Tiotropium + olodaterol in patients with moderate to severe COPD with chronic bronchitis and/or emphysema

Autor: Eric Derom, Roland Buhl, Lars Grönke, Florian Voß, Leif Bjermer, Matjaz Flezar

Publikováno v: Pneumologie. 71:S1-S125

Introduction: Chronic bronchitis and emphysema are two COPD phenotypes that can affect pharmacologic treatment decisions. Aims: Tiotropium (T) + olodaterol (O) was established for COPD treatment in two large Phase III trials. This post hoc analysis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbd0e3c3fdec8c69e967d8c273c840c
https://doi.org/10.1055/s-0037-1598308

Effects of baseline symptom burden on treatment response in COPD

Autor: Gary T. Ferguson, Dave Singh, Roger Abrahams, Florian Voß, Leif Bjermer, Fernando J. Martinez, Lars Grönke

Publikováno v: Martinez, F J, Abrahams, R A, Ferguson, G T, Bjermer, L, Grönke, L, Voß, F & Singh, D 2019, ' Effects of baseline symptom burden on treatment response in COPD ', International journal of chronic obstructive pulmonary disease, vol. 14, pp. 181-194 . https://doi.org/10.2147/COPD.S179912
International Journal of Chronic Obstructive Pulmonary Disease

Fernando J Martinez,1 Roger A Abrahams,2,3 Gary T Ferguson,4 Leif Bjermer,5 Lars Grönke,6 Florian Voß,7 Dave Singh8 1Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, NY, USA; 2Morgantown Pulmonary Clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300f219945eeb5e6e9141672fea018f5
https://pubmed.ncbi.nlm.nih.gov/30655665