Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lars G. Grunnet"'
Autor:
Shailesh Kumar Gupta, Agata Wesolowska-Andersen, Anna K. Ringgaard, Himjyot Jaiswal, Luyan Song, Benoit Hastoy, Camilla Ingvorsen, Amir Taheri-Ghahfarokhi, Björn Magnusson, Marcello Maresca, Rikke R. Jensen, Nicola L. Beer, Johannes J. Fels, Lars G. Grunnet, Melissa K. Thomas, Anna L. Gloyn, Ryan Hicks, Mark I. McCarthy, Mattias Hansson, Christian Honoré
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 220-231 (2018)
Recent studies have reported significant advances in the differentiation of human pluripotent stem cells to clinically relevant cell types such as the insulin producing beta-like cells and motor neurons. However, many of the current differentiation p
Externí odkaz:
https://doaj.org/article/388e243f0c3f452f8d7167f3e381a0f1
Autor:
Wanjun Liu, James A. Flanders, Long‐Hai Wang, Qingsheng Liu, Daniel T. Bowers, Kai Wang, Alan Chiu, Xi Wang, Alexander U. Ernst, Kaavian Shariati, Julia S. Caserto, Benjamin Parker, Daqian Gao, Mitchell D. Plesser, Lars G. Grunnet, Claude Rescan, Rodrigo Pimentel Carletto, Louise Winkel, Juan M. Melero‐Martin, Minglin Ma
Publikováno v:
Small
Encapsulation and transplantation of insulin-producing cells offer a promising curative treatment for type 1 diabetes (T1D) without immunosuppression. However, biomaterials used to encapsulate cells often elicit foreign body responses, leading to cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03986a0c38150959d36de6069647cfa8
https://europepmc.org/articles/PMC8881301/
https://europepmc.org/articles/PMC8881301/
Autor:
Reid Aikin, Thomas Mandrup-Poulsen, Lykke Blaabjerg, Steven Paraskevas, Lawrence Rosenberg, Lars G. Grunnet, Dusica Maysinger, Joachim Størling, Nils Billestrup, Morten Tonnesen
Publikováno v:
Diabetes
OBJECTIVE Proinflammatory cytokines are cytotoxic to β-cells and have been implicated in the pathogenesis of type 1 diabetes and islet graft failure. The importance of the intrinsic mitochondrial apoptotic pathway in cytokine-induced β-cell death i
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10843 (2010)
BACKGROUND: Prolonged periods of high glucose exposure results in human islet dysfunction in vitro. The underlying mechanisms behind this effect of high glucose are, however, unknown. The polypyrimidine tract binding protein (PTB) is required for sta
Externí odkaz:
https://doaj.org/article/a057318e70be4f2b9769aadfbf161188