Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Lars G, Hemkens"'
Autor:
Marius Goldkuhle, Caroline Hirsch, Claire Iannizzi, Ana-Mihaela Zorger, Ralf Bender, Elvira C. van Dalen, Lars G. Hemkens, Ina Monsef, Nina Kreuzberger, Nicole Skoetz
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Time-to-event analysis is associated with methodological complexities. Previous research identified flaws in the reporting of time-to-event analyses in randomized trial publications. These hardships impose challenges for meta-anal
Externí odkaz:
https://doaj.org/article/3cff55c79b854344aed22a295ea2fe35
Autor:
Ingeborg Hess Elgersma, Petter Elstrøm, Lars G. Hemkens, Arnfinn Helleve, Oliver Kacelnik, Atle Fretheim
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/85040931cb704cd59e8acddf6288198f
Autor:
Perrine Janiaud, Chiara Zecca, Anke Salmen, Pascal Benkert, Sabine Schädelin, Annette Orleth, Lilian Demuth, Aleksandra Maleska Maceski, Cristina Granziera, Johanna Oechtering, David Leppert, Tobias Derfuss, Lutz Achtnichts, Oliver Findling, Patrick Roth, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Robert Hoepner, Giulio Disanto, Claudio Gobbi, Leila Rooshenas, Matthias Schwenkglenks, Mark J. Lambiris, Ludwig Kappos, Jens Kuhle, Özgür Yaldizli, Lars G. Hemkens
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Treatment decisions for persons with relapsing–remitting multiple sclerosis (RRMS) rely on clinical and radiological disease activity, the benefit-harm profile of drug therapy, and preferences of patients and physicians. However
Externí odkaz:
https://doaj.org/article/2dbdfb286bde4ad5a8fa355b8dcd0b9d
Methodological Challenges when Using Routinely Collected Health Data for Research: A scoping review.
Autor:
Lili Wei, Ellen Kuenzig, James Im, Yan Zheng, Taylor McLinden, Scott Emerson, Azza Eissa, Henry Halder, Richard Shaw, An-Wen Chan, William Dixon, Vera Ehrenstein, Astrid Guttmann, Katie Harron, Lars G. Hemkens, Asbjørn Hróbjartsson, Ronan Lyons, Shannon E. MacDonald, Jerry Maniate, David Moher, Irene Petersen, Hude Quan, Sigrún Schmidt, Henrik Sørensen, Shirley Wang, David A. McAllister, Sinéad M. Langan, Eric I. Benchimol
Publikováno v:
International Journal of Population Data Science, Vol 9, Iss 5 (2024)
Routinely collected health data (RCD) including electronic health records, disease registries, health administrative data and wearables data are not specifically collected for research purposes. Analysis of these data poses unique methodological chal
Externí odkaz:
https://doaj.org/article/e94b42734b89427b9eeeecef0bb6e9d2
Publikováno v:
BMJ Health & Care Informatics, Vol 31, Iss 1 (2024)
Background Technological devices such as smartphones, wearables and virtual assistants enable health data collection, serving as digital alternatives to conventional biomarkers. We aimed to provide a systematic overview of emerging literature on ‘d
Externí odkaz:
https://doaj.org/article/76abd7edd742491d8b4e1d816fd6044e
Autor:
Hualin Lüthi, Sophia Lengsfeld, Thilo Burkard, Andrea Meienberg, Nica Jeanloz, Tanja Vukajlovic, Katja Bologna, Michelle Steinmetz, Cemile Bathelt, Clara O. Sailer, Mirjam Laager, Deborah R. Vogt, Lars G. Hemkens, Benjamin Speich, Sandrine A. Urwyler, Jill Kühne, Fabienne Baur, Linda N. Lutz, Tobias E. Erlanger, Mirjam Christ-Crain, Bettina Winzeler
Publikováno v:
EClinicalMedicine, Vol 68, Iss , Pp 102429- (2024)
Summary: Background: Smoking cessation is challenging, despite making use of established smoking cessation therapies. Preclinical studies and one clinical pilot study suggest the antidiabetic drug glucagon-like peptide-1 (GLP-1) analogue to modulate
Externí odkaz:
https://doaj.org/article/8c47a01a7b914ca09c486ee55de1736c
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-8 (2023)
Abstract Background Pragmatic trials provide decision-oriented, real-world evidence that is highly applicable and generalizable. The interest in real-world evidence is fueled by the assumption that effects in the “real-world” are different to eff
Externí odkaz:
https://doaj.org/article/65a0046345664f6aa6887b77ffa949c1
Autor:
Cathrine Axfors, Andreas M. Schmitt, Perrine Janiaud, Janneke van’t Hooft, Sherief Abd-Elsalam, Ehab F. Abdo, Benjamin S. Abella, Javed Akram, Ravi K. Amaravadi, Derek C. Angus, Yaseen M. Arabi, Shehnoor Azhar, Lindsey R. Baden, Arthur W. Baker, Leila Belkhir, Thomas Benfield, Marvin A. H. Berrevoets, Cheng-Pin Chen, Tsung-Chia Chen, Shu-Hsing Cheng, Chien-Yu Cheng, Wei-Sheng Chung, Yehuda Z. Cohen, Lisa N. Cowan, Olav Dalgard, Fernando F. de Almeida e Val, Marcus V. G. de Lacerda, Gisely C. de Melo, Lennie Derde, Vincent Dubee, Anissa Elfakir, Anthony C. Gordon, Carmen M. Hernandez-Cardenas, Thomas Hills, Andy I. M. Hoepelman, Yi-Wen Huang, Bruno Igau, Ronghua Jin, Felipe Jurado-Camacho, Khalid S. Khan, Peter G. Kremsner, Benno Kreuels, Cheng-Yu Kuo, Thuy Le, Yi-Chun Lin, Wu-Pu Lin, Tse-Hung Lin, Magnus Nakrem Lyngbakken, Colin McArthur, Bryan J. McVerry, Patricia Meza-Meneses, Wuelton M. Monteiro, Susan C. Morpeth, Ahmad Mourad, Mark J. Mulligan, Srinivas Murthy, Susanna Naggie, Shanti Narayanasamy, Alistair Nichol, Lewis A. Novack, Sean M. O’Brien, Nwora Lance Okeke, Léna Perez, Rogelio Perez-Padilla, Laurent Perrin, Arantxa Remigio-Luna, Norma E. Rivera-Martinez, Frank W. Rockhold, Sebastian Rodriguez-Llamazares, Robert Rolfe, Rossana Rosa, Helge Røsjø, Vanderson S. Sampaio, Todd B. Seto, Muhammad Shahzad, Shaimaa Soliman, Jason E. Stout, Ireri Thirion-Romero, Andrea B. Troxel, Ting-Yu Tseng, Nicholas A. Turner, Robert J. Ulrich, Stephen R. Walsh, Steve A. Webb, Jesper M. Weehuizen, Maria Velinova, Hon-Lai Wong, Rebekah Wrenn, Fernando G. Zampieri, Wu Zhong, David Moher, Steven N. Goodman, John P. A. Ioannidis, Lars G. Hemkens
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/eaaad84f79e74e2bbfb5c0c8a4146fc5
Autor:
Sophia Lengsfeld, Thilo Burkard, Andrea Meienberg, Nica Jeanloz, David Coynel, Deborah R. Vogt, Lars G. Hemkens, Benjamin Speich, Davide Zanchi, Tobias E. Erlanger, Mirjam Christ-Crain, Bettina Winzeler
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Cigarette smoking is the leading preventable cause of premature death. Despite dedicated programmes, quit rates remain low due to barriers such as nicotine withdrawal syndrome or post-cessation weight gain. Glucagon-like peptide-1
Externí odkaz:
https://doaj.org/article/44510571840b4e0ba0925baafd2209e3
Autor:
Martin Holst, Martin Haslberger, Samruddhi Yerunkar, Daniel Strech, Lars G Hemkens, Benjamin G Carlisle
Publikováno v:
PLoS Medicine, Vol 20, Iss 10, p e1004306 (2023)
BackgroundClinical trial registries allow assessment of deviations of published trials from their protocol, which may indicate a considerable risk of bias. However, since entries in many registries can be updated at any time, deviations may go unnoti
Externí odkaz:
https://doaj.org/article/e9359674fed0453ca37d80b992ea5b4b