Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Lars Endahl"'
Autor:
Martin Haljeta Friedrichsen, Lars Endahl, Frederik Flindt Kreiner, Ronald Goldwater, Martin Kankam, Søren Toubro, Sune Boris Nygård
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102023- (2024)
Externí odkaz:
https://doaj.org/article/a2cb6b12f7a44bd6b4923aaac9fbb43b
Autor:
Martin Haljeta Friedrichsen, Lars Endahl, Frederik Flindt Kreiner, Ronald Goldwater, Martin Kankam, Søren Toubro, Sune Boris Nygård
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101801- (2023)
Objective: Glucagon/glucagon-like peptide-1 (GLP-1) receptor co-agonists may provide greater weight loss than agonists targeting the GLP-1 receptor alone. We report results from three phase 1 trials investigating the safety, tolerability, pharmacokin
Externí odkaz:
https://doaj.org/article/b2b05f65c82543e7ad21889e4403b00b
Autor:
Jena S. Tronieri, Anthony N. Fabricatore, Thomas A. Wadden, Pernille Auerbach, Lars Endahl, Danny Sugimoto, Domenica Rubino
Publikováno v:
Obesity Facts, Pp 1-12 (2020)
Introduction: Individuals who enroll in intensive behavioral therapy (IBT) programs are asked to make several lifestyle changes simultaneously. However, few studies have examined the relative effects of adherence to different treatment components on
Externí odkaz:
https://doaj.org/article/aaa1ff0326af4e3b81c7284095a98686
Autor:
Martin Friedrichsen, Lars Endahl, Frederik Flindt Kreiner, Ronald Goldwater, Martin Kankam, Søren Toubro, Sune Boris Nygård
Glucagon/glucagon-like peptide-1 (GLP-1) receptor co-agonists may provide greater weight loss than agonists targeting the GLP-1 receptor alone. We report results from three phase 1 trials investigating the glucagon/GLP-1 receptor co-agonist NNC9204-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0279893abdd346210ed65916e905ec0e
https://doi.org/10.1101/2022.06.02.22275920
https://doi.org/10.1101/2022.06.02.22275920
Autor:
Lars Endahl, Michael E. J. Lean, Dorthe Skovgaard, John P.H. Wilding, Sean Wharton, Thomas A. Wadden, Altynai Satylganova, Arne Astrup
Publikováno v:
International Journal of Obesity (2005)
Wharton, S, Astrup, A, Endahl, L, Lean, M E J, Satylganova, A, Skovgaard, D, Wadden, T A & Wilding, J P H 2021, ' Estimating and reporting treatment effects in clinical trials for weight management: Using estimands to interpret effects of intercurrent events and missing data ', International Journal of Obesity, vol. 45, pp. 923-933 . https://doi.org/10.1038/s41366-020-00733-x
Wharton, S, Astrup, A, Endahl, L, Lean, M E J, Satylganova, A, Skovgaard, D, Wadden, T A & Wilding, J P H 2021, ' Estimating and reporting treatment effects in clinical trials for weight management: Using estimands to interpret effects of intercurrent events and missing data ', International Journal of Obesity, vol. 45, pp. 923-933 . https://doi.org/10.1038/s41366-020-00733-x
In the approval process for new weight management therapies, regulators typically require estimates of effect size. Usually, as with other drug evaluations, the placebo-adjusted treatment effect (i.e., the difference between weight losses with pharma
Autor:
Lars Endahl, Shawn Hoskin, Inger Mollerup, Anders Hvelplund, Alan C. Moses, Hanne Theilgaard, Ida Carøe Helmark, Lene Klixbüll Amby
Publikováno v:
Therapeutic Innovation & Regulatory Science. 53:279-286
In 2013, a randomized, double-blind, active comparator-controlled, event-driven cardiovascular outcomes trial (DEVOTE) was initiated to compare the cardiovascular safety of insulin degludec (degludec) versus insulin glargine 100 units/mL (glargine U1
Autor:
Lars Endahl, Jena Shaw Tronieri, Thomas A. Wadden, Anthony N. Fabricatore, Domenica Rubino, Pernille Auerbach, Danny Sugimoto
Publikováno v:
Obesity Facts, Pp 1-12 (2020)
Obes Facts
Obes Facts
Introduction: Individuals who enroll in intensive behavioral therapy (IBT) programs are asked to make several lifestyle changes simultaneously. However, few studies have examined the relative effects of adherence to different treatment components on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c01460f7880e79278d4766f1a16189
https://www.karger.com/Article/FullText/511130
https://www.karger.com/Article/FullText/511130
Autor:
Lars Endahl, Thomas A. Wadden, Domenica Rubino, Daniel Sugimoto, Pernille Auerbach, Jena Shaw Tronieri, Michael T. Lund
Publikováno v:
Journal of the Endocrine Society
The objective of the SCALE IBT trial (NCT02963935) was to compare the weight loss of liraglutide 3.0 mg, a medication approved by the Food and Drug Administration for chronic weight management, to placebo, both in combination with 56 weeks of intensi
Autor:
Lars Endahl, Domenica Rubino, Jena Shaw Tronieri, Michael T. Lund, Thomas A. Wadden, Pernille Auerbach, Daniel Sugimoto
Publikováno v:
Journal of the Endocrine Society
Liraglutide 3.0 mg is approved by the Food and Drug Administration for chronic weight management in the United States as an adjunct to reduced caloric diet and increased physical activity. The objective of the SCALE IBT trial (NCT02963935) was to com
Publikováno v:
Diabetic Medicine
Aims To investigate, in a 26‐week, open‐label, randomized, treat‐to‐target trial, the efficacy and safety of insulin degludec/insulin aspart (IDegAsp) once daily vs insulin glargine (IGlar) once daily in adults with Type 2 diabetes, inadequat