Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lars E. Clark"'
Autor:
Pan Yang, Wanyu Li, Xiaoyi Fan, Junhua Pan, Colin J. Mann, Haley Varnum, Lars E. Clark, Sarah A. Clark, Adrian Coscia, Himanish Basu, Katherine Nabel Smith, Vesna Brusic, Jonathan Abraham
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Eastern equine encephalitis virus (EEEV) is the most virulent alphavirus that infects humans, and many survivors develop neurological sequelae, including paralysis and intellectual disability. Alphavirus spike proteins comprise trimers of he
Externí odkaz:
https://doaj.org/article/3558839e2a8445dfb2e6a4a3663d9da4
Autor:
Brady T. Hickerson, Tracy R. Daniels-Wells, Cristian Payes, Lars E. Clark, Pierre V. Candelaria, Kevin W. Bailey, Eric J. Sefing, Samantha Zink, James Ziegenbein, Jonathan Abraham, Gustavo Helguera, Manuel L. Penichet, Brian B. Gowen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Five New World mammarenaviruses (NWMs) enter cells via binding to human transferrin receptor 1 (hTfR1). Here, Hickerson et al. show that hTfR1 targeting antibodies partially protect hTfR1-transgenic mice from lethal NWM challenge via competition of a
Externí odkaz:
https://doaj.org/article/e61379f33d29440ab73ec6d55d625606
Autor:
Lars E. Clark, Selma Mahmutovic, Donald D. Raymond, Taleen Dilanyan, Takaaki Koma, John T. Manning, Sundaresh Shankar, Silvana C. Levis, Ana M. Briggiler, Delia A. Enria, Kai W. Wucherpfennig, Slobodan Paessler, Jonathan Abraham
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The five known New World hemorrhagic fever arenaviruses use the same entry receptor, but their viral glycoproteins are markedly different. Here, the authors isolate monoclonal antibodies from a Junin virus vaccinated person that cross-neutralize Mach
Externí odkaz:
https://doaj.org/article/daef1e9d51b8461ba2ffa8c665295132
Autor:
Sol Ferrero, Maria D. Flores, Connor Short, Cecilia A. Vazquez, Lars E. Clark, James Ziegenbein, Samantha Zink, Daniel Fuentes, Cristian Payes, María V. Batto, Michael Collazo, Cybele C. García, Jonathan Abraham, Sandra M. Cordo, Jose A. Rodriguez, Gustavo Helguera
Publikováno v:
Journal of Virology. 96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f8ddc4efb8996de5851c15f8978536
https://doi.org/10.1128/jvi.02163-21
https://doi.org/10.1128/jvi.02163-21
Autor:
Katherine G. Nabel, Sarah A. Clark, Sundaresh Shankar, Junhua Pan, Lars E. Clark, Pan Yang, Adrian Coscia, Lindsay G. A. McKay, Haley H. Varnum, Vesna Brusic, Nicole V. Tolan, Guohai Zhou, Michaël Desjardins, Sarah E. Turbett, Sanjat Kanjilal, Amy C. Sherman, Anand Dighe, Regina C. LaRocque, Edward T. Ryan, Casey Tylek, Joel F. Cohen-Solal, Anhdao T. Darcy, Davide Tavella, Anca Clabbers, Yao Fan, Anthony Griffiths, Ivan R. Correia, Jane Seagal, Lindsey R. Baden, Richelle C. Charles, Jonathan Abraham
Publikováno v:
Science
Many studies have examined the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants on neutralizing antibody activity after they have become dominant strains. Here, we evaluate the consequences of further viral evolution. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9850b307f3dab4d7e12ef6670e46c550
https://doi.org/10.1126/science.abl6251
https://doi.org/10.1126/science.abl6251
Autor:
Brady T. Hickerson, Tracy R. Daniels-Wells, Cristian Payes, Lars E. Clark, Pierre V. Candelaria, Kevin W. Bailey, Eric J. Sefing, Samantha Zink, James Ziegenbein, Jonathan Abraham, Gustavo Helguera, Manuel L. Penichet, Brian B. Gowen
Publikováno v:
Nature Communications
Nature communications, vol 13, iss 1
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Nature communications, vol 13, iss 1
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Five New World mammarenaviruses (NWMs) cause life-threatening hemorrhagic fever (HF). Cellular entry by these viruses is mediated by human transferrin receptor 1 (hTfR1). Here, we demonstrate that an antibody (ch128.1/IgG1) which binds the apical dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e169f595bae8bee27c8dbe39db970d59
https://pubmed.ncbi.nlm.nih.gov/35091550
https://pubmed.ncbi.nlm.nih.gov/35091550