Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lars D. Maerz"'
Autor:
Martin D. Burkhalter, Tom Stiff, Lars D. Maerz, Teresa Casar Tena, Heike Wiese, Julian Gerhards, Steffen A. Sailer, Linh Anna Trúc Vu, Max Duong Phu, Cornelia Donow, Marius Alupei, Sebastian Iben, Marco Groth, Sebastian Wiese, Joseph A. Church, Penelope A. Jeggo, Melanie Philipp
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)
Abstract The WD repeat-containing protein 4 (WDR4) has repeatedly been associated with primary microcephaly, a condition of impaired brain and skull growth. Often, faulty centrosomes cause microcephaly, yet aberrant cilia may also be involved. Here,
Externí odkaz:
https://doaj.org/article/c7c8e616bb0a44d686f248d5e16d846c
Autor:
Julian Gerhards, Lars D. Maerz, Edda S. F. Matthees, Cornelia Donow, Barbara Moepps, Richard T. Premont, Martin D. Burkhalter, Carsten Hoffmann, Melanie Philipp
Publikováno v:
Journal of the American Society of Nephrology. 34:590-606
Autor:
David P. Dannheisig, Astrid S. Pfister, Maria T. Meyer, Melanie Philipp, Lars D. Maerz, Marina Keil
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:882-895
The nucleolus is a subnuclear compartment, which governs ribosome biogenesis. Moreover, it functions as hub in the stress response by orchestrating a variety of processes, such as regulation of cell cycle progression, senescence and apoptosis. Emergi
Autor:
Julian Gerhards, Penny A. Jeggo, Lars D. Maerz, Cornelia Donow, Teresa Casar Tena, Melanie Philipp
Meier–Gorlin syndrome (MGS) is a rare, congenital primordial microcephalic dwarfism disorder. MGS is caused by genetic variants of components of the origin recognition complex (ORC) consisting of ORC1–6 and the pre-replication complex, which toge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fcbe815684518834c13b34d58a4914
Autor:
Alush I, Avila, Anett, Illing, Friedrich, Becker, Lars D, Maerz, Yohei, Morita, Melanie, Philipp, Martin D, Burkhalter
Publikováno v:
Nucleic Acids Research
Reduced capacity of genome maintenance represents a problem for any organism, potentially causing premature death, carcinogenesis, or accelerated ageing. Strikingly though, loss of certain genome stability factors can be beneficial, especially for th