Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lars C. Holzhausen"'
Autor:
Ashley A George, Sara Hayden, Lars C Holzhausen, Eva Y Ma, Sachihiro C Suzuki, Susan E Brockerhoff
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84394 (2014)
Highly polarized cells such as photoreceptors require precise and efficient strategies for establishing and maintaining the proper subcellular distribution of proteins. The signals and molecular machinery that regulate trafficking and sorting of syna
Externí odkaz:
https://doaj.org/article/23b32bad8b6647ec833c44fa0724b42b
Publikováno v:
eNeuro, vol 7, iss 5
eNeuro
eNeuro
Horizontal cells (HCs) form reciprocal synapses with rod and cone photoreceptors, an arrangement that underlies lateral inhibition in the retina. HCs send negative and positive feedback signals to photoreceptors, but how HCs initiate these signals re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffa1611b3cb8da6e31cb22bd3661431
https://escholarship.org/uc/item/0g1828r1
https://escholarship.org/uc/item/0g1828r1
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 39, iss 4
Lateral inhibition in the vertebrate retina depends on a negative feedback synapse between horizontal cells (HCs) and rod and cone photoreceptors. A change in pH is thought to be the signal for negative feedback, but its spatial profile in the synapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bcb1639e144d012227aa8d46d1ca8b9
https://escholarship.org/uc/item/1zg218dh
https://escholarship.org/uc/item/1zg218dh
Publikováno v:
The Journal of Comparative Neurology. 517:633-644
Synaptojanin 1 (SynJ1) is a polyphosphoinositide phosphatase involved in clathrin-mediated endocytosis in conventional synapses. Studies with the zebrafish mutant nrc have revealed that loss of SynJ1 also affects cone photoreceptor ribbon synapses, c
Autor:
Marcelo Gil Araujo, Heinrich Bollwein, M. Heppelmann, C. Pfarrer, Hans-Joachim Schuberth, Anja Sipka, Marion Piechotta, Lars C. Holzhausen
Publikováno v:
Journal of Veterinary Science
Cows with different Insulin-like Growth Factor-I (IGF-I) concentrations showed comparable expression levels of hepatic growth hormone receptor (GHR). Suppressor of cytokine signaling 2 (SOCS2), could be responsible for additional inhibition of the GH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5f0df284a4cade34e69cdabc26ba44
https://doi.org/10.5167/uzh-107162
https://doi.org/10.5167/uzh-107162
Publikováno v:
Nature neuroscience
The reciprocal synapse between photoreceptors and horizontal cells underlies lateral inhibition and establishes the antagonistic center-surround receptive fields of retinal neurons to enhance visual contrast. Despite decades of study, the signal medi
Autor:
Eva Y. Ma, Lars C. Holzhausen, Sachihiro C. Suzuki, Susan E. Brockerhoff, Ashley A. George, Sara Hayden
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e84394 (2014)
PLoS ONE, Vol 9, Iss 1, p e84394 (2014)
Highly polarized cells such as photoreceptors require precise and efficient strategies for establishing and maintaining the proper subcellular distribution of proteins. The signals and molecular machinery that regulate trafficking and sorting of syna
Publikováno v:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 24(2)
A 15-year-old gelding presented with a progressive lameness of the left forelimb of 2.5 months duration. Clinically, a dilation of the deep flexor tendon sheath with a firm elastic consistency and a pronounced tenderness was noted. Ultrasonically, a
Autor:
Drew Couron, Jonathan D. Linton, Iok Teng Kuok, Edward D Parker, Andrei O. Chertov, James B. Hurley, Martin Sadilek, Lars C. Holzhausen, Ian R. Sweet
Vertebrate photoreceptor neurons have a high demand for metabolic energy, and their viability is very sensitive to genetic and environmental perturbations. We investigated the relationship between energy metabolism and cell death by evaluating the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1154211c58b1d47d75b53c1294f125c1
https://europepmc.org/articles/PMC3186402/
https://europepmc.org/articles/PMC3186402/
Autor:
Hongman Song, Kiyoharu J. Miyagishima, Theo A. Peters, Willam N. Zagotta, Wallace B. Thoreson, Helma Pluk, Romeo Caffe, Mathias W. Seeliger, George W. Stearns, Norbert Babai, Andrei O. Chertov, James B. Hurley, Edward D Parker, Ellen Townes-Anderson, Catharina E.E.M. Van der Zee, Gabriel H. Travis, Ian R. Sweet, Jonathan D. Linton, Lars C. Holzhausen, J. Wei, Theodore M. Bartoletti, Kimberly K. Fong, Ken J. Lindsay, Naoyuki Tanimoto, Laura Bolton, Denise L T Kuok, Maxim Sokolov, Roxana A. Radu, Alapakkam P. Sampath
Publikováno v:
Proceedings of the National Academy of Sciences USA, 107, 19, pp. 8599-604
Proceedings of the National Academy of Sciences USA, 107, 8599-604
Proceedings of the National Academy of Sciences USA, 107, 8599-604
Contains fulltext : 88596.pdf (Publisher’s version ) (Closed access) Structural features of neurons create challenges for effective production and distribution of essential metabolic energy. We investigated how metabolic energy is distributed betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236dcfa3540c6d484397a36dab635d6f
https://doi.org/10.1073/pnas.1002471107
https://doi.org/10.1073/pnas.1002471107