Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lars C. Doehring"'
Autor:
Heribert Schunkert, Sandra Wrobel, Zouhair Aherrahrou, Redouane Aherrahrou, Lars C. Doehring, Jeanette Erdmann, Juliane Eckhold, Piotr M. Kaczmarek, Ann-Kathrin Sowa, Frank J. Kaiser, Thorsten Kessler
Publikováno v:
The American Journal of Pathology. 183:60-68
Loss of Abcc6 gene expression was identified to be responsible for dystrophic calcification of the heart (DCC) or vessels after acute injury in several strains of laboratory mice. This calcification shares features with osteogenesis and may involve o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d3c865bf5cc12049582c725ec823cd
https://doi.org/10.1016/j.ajpath.2013.03.007
https://doi.org/10.1016/j.ajpath.2013.03.007
Autor:
Heribert Schunkert, Piotr M. Kaczmarek, Jeanette Erdmann, Eva-Maria Ehlers, Lars C. Doehring, Zouhair Aherrahrou, Christian Heeger
Publikováno v:
The American Journal of Pathology. 177:473-480
Chondrogenic differentiation is pivotal in the active regulation of artery calcification. We investigated the cellular origin of chondrocyte-like cells in atherosclerotic intimal calcification of C57BL/6 LDLr(-/-) mice using bone marrow transplantati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8b53b40949660e535e5a989b1a8711
https://doi.org/10.2353/ajpath.2010.090758
https://doi.org/10.2353/ajpath.2010.090758
Autor:
Jeanette Erdmann, Patrick Linsel-Nitschke, Henrike Liptau, Reinhard Depping, Piotr M. Kaczmarek, Eva-Maria Ehlers, Heribert Schunkert, Zouhair Aherrahrou, Lars C. Doehring
Publikováno v:
Journal of Biological Chemistry. 283:7608-7615
Dystrophic cardiac calcification (DCC) is an autosomal recessive trait characterized by calcium phosphate deposits in myocardial tissue. The Abcc6 gene locus was recently found to mediate DCC; however, at the molecular level the causative variants re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589299681657e99cbe2f7bdc32067b64
https://doi.org/10.1074/jbc.m708290200
https://doi.org/10.1074/jbc.m708290200
Autor:
Peter W. Radke, Hans-Werner Hense, Henrike Liptau, Björn Mayer, Jeanette Erdmann, Andrea Bässler, Heribert Schunkert, Marcus Fischer, Lars C. Doehring, Anika Götz, Stephan R. Holmer, Zouhair Aherrahrou, Wolfgang Lieb, Christian Hengstenberg
Publikováno v:
Journal of Hypertension. 25:1731-1738
OBJECTIVES Coronary artery calcification (CAC) determined by electron beam computed tomography is a predictor of future cardiovascular events. This study investigates conditions affecting CAC severity in patients with coronary artery disease (CAD) un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71d4b6d2517602807e56e97a00789f6
https://doi.org/10.1097/hjh.0b013e328165cbb6
https://doi.org/10.1097/hjh.0b013e328165cbb6
Autor:
Eva-Maria Ehlers, Sandra Wrobel, Piotr M. Kaczmarek, Andrea Pomarino, Anika Götz, Jeanette Erdmann, Lars C. Doehring, Heribert Schunkert, Zouhair Aherrahrou, Henrike Liptau, Bjoern Mayer
Publikováno v:
Physiological Genomics. 28:203-212
In mice, dystrophic cardiovascular calcification (DCC) is controlled by a major locus on proximal mouse chromosome 7 named Dyscalc1. Here we present a strategy that combines in silico analysis, expression analysis, and extensive sequencing for ultraf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc65f3d0c44612dd10ba28b1f943055a
https://doi.org/10.1152/physiolgenomics.00133.2006
https://doi.org/10.1152/physiolgenomics.00133.2006
Autor:
Hugo A. Katus, Piotr M. Kaczmarek, Susanne Korff, Boris Ivandic, Lars C. Doehring, Dieter Weichenhan, Zouhair Aherrahrou, Alexandra Jurat, Susanne B. Axtner
Publikováno v:
The American Journal of Pathology. 164:1379-1387
Calcification of necrotic tissue is frequently observed in chronic inflammation and atherosclerosis. A similar response of myocardium to injury, referred to as dystrophic cardiac calcinosis (DCC), occurs in certain inbred strains of mice. We now exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d1b83bdf2db75613e6952263331ee7
https://doi.org/10.1016/s0002-9440(10)63224-5
https://doi.org/10.1016/s0002-9440(10)63224-5
Autor:
Lars C. Doehring, Piotr M. Kaczmarek, Eva-M. Ehlers, Jeanette Erdmann, Zouhair Aherrahrou, Heribert Schunkert, Björn Mayer
Publikováno v:
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 188(3)
Vascular calcification is highly correlated with atherosclerosis and cardiovascular disease and is a significant predictor of cardiovascular morbidity and mortality. Studies in mice indicate a genetic contribution to this dystrophic extra osseous cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244259fc988ea10d1bd97970da2de70c
https://pubmed.ncbi.nlm.nih.gov/16711162
https://pubmed.ncbi.nlm.nih.gov/16711162