Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lars Buechler"'
Autor:
Paul. B. Sinclair, Helen H. Blair, Sarra L. Ryan, Lars Buechler, Joanna Cheng, Jake Clayton, Rebecca Hanna, Shaun Hollern, Zoe Hawking, Matthew Bashton, Claire J. Schwab, Lisa Jones, Lisa J. Russell, Helen Marr, Peter Carey, Christina Halsey, Olaf Heidenreich, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal mod
Externí odkaz:
https://doaj.org/article/061b963a6e4f465eb098f328b26facdc
Autor:
Joanna Cheng, Christina Halsey, Matthew Bashton, Paul Sinclair, Shaun Hollern, Helen Marr, Peter Carey, Lars Buechler, Jake Clayton, Rebecca Hanna, Sarra Ryan, Helen J. Blair, Christine J. Harrison, Olaf Heidenreich, Zoe Hawking, Claire Schwab, Anthony V. Moorman, Lisa Jones, Lisa J. Russell
Publikováno v:
Haematologica
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d6a3be31ae824af1930e9517a6dab
https://eprints.gla.ac.uk/157726/13/157726.pdf
https://eprints.gla.ac.uk/157726/13/157726.pdf
Autor:
Alex Elder, Lars Buechler, Frida Ponthan, Chris M. Bacon, Josef Vormoor, Olaf Heidenreich, Helen J. Blair, Simon Bomken, Klaus Rehe
Publikováno v:
Leukemia. 27:718-721
Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows in vivo tracking of disease progression
Autor:
Sirintra Nakjang, Sarra Ryan, Paul Sinclair, Olaf Heidenreich, Lars Buechler, Helen J. Blair, Prahlad V. Raninga, Joanna Cheng, Amir Enshaei, Shaun Hollern, Christine J. Harrison, Jeyanthy Eswaran, Rebecca Hanna
Publikováno v:
Blood. 126:2449-2449
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is accompanied by genomic mutations and rearrangements that commonly affect cytokines, transcription factors or signalling molecules that drive B-cell development or contribute to the pre-B cell
Autor:
Paul Sinclair, Lisa J. Russell, Jake Clayton, Lisa Jones, Lars Buechler, Joanna Cheng, Claire Schwab, Olaf Heidenreich, Bryan D. Young, Christine J. Harrison, Helen J. Blair
Publikováno v:
Blood. 122:2485-2485
Insight into the role of recurrent genomic changes arising in leukemia has depended largely on the functional analysis of cell lines and transgenic animals. However not all acquired abnormalities are represented in available cell lines and a few are
Autor:
Josef Vormoor, Olaf Heidenreich, Helen J. Blair, Lars Buechler, Klaus Rehe, Simon Bomken, Frida Ponthan
Publikováno v:
Web of Science
Abstract 4000 Serial transplantation of patient derived acute lymphoblastic leukaemia (ALL) blasts continues to contribute to our understanding of the biology of leukaemia stem cells (LSC). Refinement of techniques, and in particular intrafemoral inj
Autor:
Frida Ponthan, Lars Buechler, Hesta McNeill, Josef Vormoor, Olaf Heidenreich, Vasily V. Grinev
Publikováno v:
Blood. 118:2455-2455
Abstract 2455 Background: MLL/AF4 and AML1/MTG8 are fusion genes most frequently found in infant acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML), respectively. We have previously shown that transient siRNA mediated knock-down of