Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lars Boukharta Persson"'
Autor:
Lionel Trésaugues, Kilian Huber, Ioanna Panagakou, Camilla Silvander, F. Rahm, Martin Andersson, Antoine Talagas, Oleg Fedorov, Marcus Bauser, Tobias Ginman, L. Diaz-Saez, Ellermann Manuel, Kenth Hallberg, Rickard Forsblom, Johan Lindström, Mátyás Gorjánácz, Anja Giese, Judith Günther, Lars Boukharta Persson, P. Siejka, Jenny Viklund, Ulrika Ericsson
Publikováno v:
Journal of Medicinal Chemistry. 61(6)
Recent literature has both suggested and questioned MTH1 as a novel cancer target. BAY-707 was just published as a target validation small molecule probe for assessing the effects of pharmacological inhibition of MTH1 on tumor cell survival, both in
Autor:
Lewis C. Cantley, Albert S. Yu, Kannan Karukarichi, Fredrik Karlsson, Ellen Santangelo, Rui Wang, F. Rahm, Ulrika Ericsson, Johan Linstrom, Mariell Pettersson, Jessica Martinsson, Tiago Braga, Madeleine Livendahl, Aine Brigette Henley, Horst Wähling, Lars Boukharta Persson, Martin Andersson, Tobias Ginman, Andreas Hoglund, Parisa Zolfaghari, Rickard Forsblom, Jenny Viklund, Lionel Trésaugues, David L. McElligott, Hyeseok Shim, Antoine Talagas, Tommy Johansson, Kesicki Edward A
Publikováno v:
Blood. 132:213-213
Phosphoinositide signaling is central to many cellular processes including the cell survival pathway known as autophagy. While there is evidence that autophagy can suppress tumorigenesis under certain circumstances, there is increasingly abundant evi