Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Lars Baltzer"'
Autor:
Lars Baltzer, Aleksandra Balliu
Publikováno v:
ChemBioChem. 18:1408-1414
The affinity for human serum albumin (HSA) of a series of 2-5 kDa peptides covalently linked to 3,5-bis[[bis(2-pyridylmethyl)amino]methyl]benzoic acid, a dipicolyl chelator with micromolar affinity for Zn2+ , was found by surface plasmon resonance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93223dd8aae89aa1e5347ded6925fa1
https://doi.org/10.1002/cbic.201700049
https://doi.org/10.1002/cbic.201700049
Publikováno v:
Bioorganicmedicinal chemistry. 25(20)
The small molecule inhibitor acetazolamide (AZM) was conjugated to a set of designed polypeptides and the resulting conjugates were evaluated for their affinity to Human Carbonic Anhydrase II (HCA II) using surface plasmon resonance. The dissociation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6d883d1655b8640fbcebf253749d84
https://pubmed.ncbi.nlm.nih.gov/28943245
https://pubmed.ncbi.nlm.nih.gov/28943245
Autor:
Jie Yang, Martin Haraldsson, Lars Baltzer, Thomas Norberg, Anna-Lena Gustavsson, Göran Karlsson
Publikováno v:
Organicbiomolecular chemistry. 15(21)
A high-affinity polypeptide conjugate 4-C25L22-DQ, has been developed for the molecular recognition of the human C-reactive protein, CRP, a well-known inflammation biomarker. CRP is one of the most frequently quantified targets in diagnostic applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674dbe34aba69b8e49bb7a2507b4cef7
https://pubmed.ncbi.nlm.nih.gov/28513744
https://pubmed.ncbi.nlm.nih.gov/28513744
Autor:
Aleksandra Balliu, Lars Baltzer
Publikováno v:
Chembiochem : a European journal of chemical biology. 18(14)
A 42-residue polypeptide conjugated to a small-molecule organic ligand capable of targeting the phosphorylated side chain of Ser15 was shown to bind glycogen phosphorylase a (GPa) with a KD value o ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171c6e75ffa90936c5a22f5c2bf3182a
https://pubmed.ncbi.nlm.nih.gov/28432776
https://pubmed.ncbi.nlm.nih.gov/28432776
Publikováno v:
Journal of Peptide Science. 19:461-469
Intrinsically disordered proteins that exist as unordered monomeric structures in aqueous solution at pH7 but fold into four-helix bundles upon binding to recognized polypeptide targets have been designed. NMR and CD spectra of the monomeric polypept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9aba9aef8f76eaf55893e47b551a96a
https://doi.org/10.1002/psc.2520
https://doi.org/10.1002/psc.2520
Autor:
D.J. Gross, Paweł Jóźków, Kevin Sinchak, Małgorzata Słowińska-Lisowska, M. Romero, Ulf Landegren, Bengt Nielsen, Malika Kachani, Bengt Långström, Fredrik Pontén, P. Reissman, Druck Reinhardt Druck Basel, Mohid S. Khan, K.I. Alexandraki, Jürgen Borlak, Marek Mędraś, Irvin M. Modlin, A. Azpiroz, Łukasz Łaczmański, Nadia Tavitian, Oscar Vegas, G.A. Kaltsas, Leonor Pinilla, Amaia Arregi, Håkan Ahlström, Eneritz Gómez-Lázaro, V. Doviner, Rafael Pineda, Larraitz Garmendia, Amanda Borgquist, Edward J. Wagner, Lars Baltzer, Joana Perez-Tejada, Ariane Sharif, Miguel A. Sánchez-Garrido, Valeria Giandomenico, S. Grozinsky-Glasberg, D. Barak, Marc Baroncini, Francisco Ruiz-Pino, Francisco Gaytán, John C. Waterton, Vincent Prevot, Satz Mengensatzproduktion, Mats Nilsson, Robert P. Millar, Jonas Bergqvist, Antonio Romero-Ruiz, Manuel Tena-Sempere, Enrique Aguilar, Kjell Öberg, Barbro Eriksson
Publikováno v:
Neuroendocrinology. 98:89-96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9030056bd7352b71306173c4f1224f49
https://doi.org/10.1159/000351615
https://doi.org/10.1159/000351615
Autor:
Bengt Långström, Lars Baltzer, Kjell Öberg, Ulf Landegren, Barbro Eriksson, Irvin M. Modlin, John C. Waterton, Robert P. Millar, Håkan Ahlström, Fredrik Pontén, Mohid S. Khan, Valeria Giandomenico, Mats Nilsson, Jürgen Borlak, Jonas Bergqvist, Bengt Nielsen
Publikováno v:
Neuroendocrinology. 98:16-30
Neuroendocrine tumors (NET) are malignant solid tumors that arise in hormone-secreting tissue of the diffuse neuroendocrine system or endocrine glands. Although traditionally understood to be a rare disease, the incidence and prevalence of NET have i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78cf556136011f91c93617505f71fbed
https://doi.org/10.1159/000348832
https://doi.org/10.1159/000348832
Publikováno v:
Journal of Peptide Science. 18:731-739
This thesis describes the design and synthesis of small molecule derivatives and their polypeptide conjugates as high affinity binders for proteins: the D-dimer protein (D-dimer), a biomarker for diagnosis of thromboembolic diseases; human myeloperox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab61d77e828e180db0f4446ec818b591
https://doi.org/10.1002/psc.2459
https://doi.org/10.1002/psc.2459
Autor:
Lars Baltzer, Pontus Forsberg, Fredrik Nikolajeff, Karin Fromell, Mikael Karlsson, Karin Larsson
Publikováno v:
Analytical and Bioanalytical Chemistry. 404:1643-1651
A platform for diagnostic applications showing signal-to-noise ratios that by far surpass those of traditional bioanalytical test formats has been developed. It combines the properties of modified nanocrystalline diamond (NCD) surfaces and those of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee78dabbcb857d2d4f730557c51fa81
https://doi.org/10.1007/s00216-012-6245-7
https://doi.org/10.1007/s00216-012-6245-7
Autor:
Lars Baltzer, Adam T. Ślósarczyk
Publikováno v:
Journal of Peptide Science. 18:261-269
The conjugation of a small organic molecule to synthetic polypeptides from a designed set has been shown to give rise to binders with high affinity and selectivity for the phosphorylated model proteins α-casein and β-casein but not for ovoalbumin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::877e58d2eab7d56591d12800dc14d9f2
https://doi.org/10.1002/psc.2394
https://doi.org/10.1002/psc.2394