Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Lars Allan Larsen"'
Autor:
Mahmood Rasool, Peter Natesan Pushparaj, Absarul Haque, Ayat Mohammed Shorbaji, Loubna Siraj Mira, Sherin Bakhashab, Mohamed Nabil Alama, Muhammad Farooq, Sajjad Karim, Lars Allan Larsen
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37177- (2024)
Background & aim: Congenital heart disease (CHD) is the most common cause of non-infectious deaths in infants worldwide. However, the molecular mechanisms underlying CHD remain unclear. Approximately 30 % of the causes are believed to be genetic muta
Externí odkaz:
https://doaj.org/article/457a87b4a9304fe2848619c2131c0d6d
Autor:
Charlotte Harken Jensen, Rikke Helin Johnsen, Tilde Eskildsen, Christina Baun, Ditte Gry Ellman, Shu Fang, Sara Thornby Bak, Svend Hvidsten, Lars Allan Larsen, Ann Mari Rosager, Lars Peter Riber, Mikael Schneider, Jo De Mey, Mads Thomassen, Mark Burton, Shizuka Uchida, Jorge Laborda, Ditte Caroline Andersen
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 2, Pp n/a-n/a (2024)
Abstract Background Heart failure due to myocardial infarction (MI) involves fibrosis driven by epicardium‐derived cells (EPDCs) and cardiac fibroblasts, but strategies to inhibit and provide cardio‐protection remains poor. The imprinted gene, no
Externí odkaz:
https://doaj.org/article/8159e282c4c94511948c59dd2e803759
Autor:
Muhammad Farooq, Louise Lindbæk, Nicolai Krogh, Canan Doganli, Cecilie Keller, Maren Mönnich, André Brás Gonçalves, Srinivasan Sakthivel, Yuan Mang, Ambrin Fatima, Vivi Søgaard Andersen, Muhammad S. Hussain, Hans Eiberg, Lars Hansen, Klaus Wilbrandt Kjaer, Jay Gopalakrishnan, Lotte Bang Pedersen, Kjeld Møllgård, Henrik Nielsen, Shahid. M. Baig, Niels Tommerup, Søren Tvorup Christensen, Lars Allan Larsen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The RRP7A a gene is involved in ribosome biogenesis. Here the authors report a homozygous missense mutation segregating with primary microcephaly, and show that this occurs via functional defects in both nucleoli and primary cilia disrupting cell pro
Externí odkaz:
https://doaj.org/article/c99a44aeca8f429fbc9fec881a09e94d
Autor:
Enrique Audain, Anna Wilsdon, Jeroen Breckpot, Jose M G Izarzugaza, Tomas W Fitzgerald, Anne-Karin Kahlert, Alejandro Sifrim, Florian Wünnemann, Yasset Perez-Riverol, Hashim Abdul-Khaliq, Mads Bak, Anne S Bassett, D Woodrow Benson, Felix Berger, Ingo Daehnert, Koenraad Devriendt, Sven Dittrich, Piers Ef Daubeney, Vidu Garg, Karl Hackmann, Kirstin Hoff, Philipp Hofmann, Gregor Dombrowsky, Thomas Pickardt, Ulrike Bauer, Bernard D Keavney, Sabine Klaassen, Hans-Heiner Kramer, Christian R Marshall, Dianna M Milewicz, Scott Lemaire, Joseph S Coselli, Michael E Mitchell, Aoy Tomita-Mitchell, Siddharth K Prakash, Karl Stamm, Alexandre F R Stewart, Candice K Silversides, Reiner Siebert, Brigitte Stiller, Jill A Rosenfeld, Inga Vater, Alex V Postma, Almuth Caliebe, J David Brook, Gregor Andelfinger, Matthew E Hurles, Bernard Thienpont, Lars Allan Larsen, Marc-Phillip Hitz
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009809 (2021)
[This corrects the article DOI: 10.1371/journal.pgen.1009679.].
Externí odkaz:
https://doaj.org/article/ee3c8898ef0a43729adf837c70afaa5a
Autor:
Anne Kathrine Møller Nielsen, Camilla Nyboe, Anne Sif Lund Ovesen, Sebastian Udholm, Malthe Mølgård Larsen, Vibeke E. Hjortdal, Lars Allan Larsen
Publikováno v:
International Journal of Cardiology Congenital Heart Disease, Vol 4, Iss , Pp 100164- (2021)
Background: In a recent nationwide cohort study, we have discovered that patients living with an atrial septal defect (ASD) have a shorter life expectancy, increased risk of atrial fibrillation, pneumonia, and psychiatric issues compared to the gener
Externí odkaz:
https://doaj.org/article/a481eaf35941450cb93c680646dc08ba
Autor:
Enrique Audain, Anna Wilsdon, Jeroen Breckpot, Jose M G Izarzugaza, Tomas W Fitzgerald, Anne-Karin Kahlert, Alejandro Sifrim, Florian Wünnemann, Yasset Perez-Riverol, Hashim Abdul-Khaliq, Mads Bak, Anne S Bassett, D Woodrow Benson, Felix Berger, Ingo Daehnert, Koenraad Devriendt, Sven Dittrich, Piers Ef Daubeney, Vidu Garg, Karl Hackmann, Kirstin Hoff, Philipp Hofmann, Gregor Dombrowsky, Thomas Pickardt, Ulrike Bauer, Bernard D Keavney, Sabine Klaassen, Hans-Heiner Kramer, Christian R Marshall, Dianna M Milewicz, Scott Lemaire, Joseph S Coselli, Michael E Mitchell, Aoy Tomita-Mitchell, Siddharth K Prakash, Karl Stamm, Alexandre F R Stewart, Candice K Silversides, Reiner Siebert, Brigitte Stiller, Jill A Rosenfeld, Inga Vater, Alex V Postma, Almuth Caliebe, J David Brook, Gregor Andelfinger, Matthew E Hurles, Bernard Thienpont, Lars Allan Larsen, Marc-Phillip Hitz
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009679 (2021)
Numerous genetic studies have established a role for rare genomic variants in Congenital Heart Disease (CHD) at the copy number variation (CNV) and de novo variant (DNV) level. To identify novel haploinsufficient CHD disease genes, we performed an in
Externí odkaz:
https://doaj.org/article/92067f3613e64d39b29f8fdaa8154ba8
Autor:
Christian Alexandro Clement, Katrine Dalsgaard Ajbro, Karen Koefoed, Maj Linea Vestergaard, Iben Rønn Veland, Maria Perestrello Ramos Henriques de Jesus, Lotte Bang Pedersen, Alexandre Benmerah, Claus Yding Andersen, Lars Allan Larsen, Søren Tvorup Christensen
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 1806-1814 (2013)
Transforming growth factor β (TGF-β) signaling is regulated by clathrin-dependent endocytosis (CDE) for the control of cellular processes during development and in tissue homeostasis. The primary cilium coordinates several signaling pathways, and t
Externí odkaz:
https://doaj.org/article/246ad0077715430ba6e57a6fb70b7a6b
Autor:
Camilla Nyboe, Anne Kathrine Møller Nielsen, Vibeke Hjortdal, Lars Allan Larsen, Sabrina Gade Ellesøe
Publikováno v:
Nielsen, A K M, Ellesøe, S G, Larsen, L A, Hjortdal, V & Nyboe, C 2022, ' Comparison of Outcome in Patients With Familial Versus Spontaneous Atrial Septal Defect ', The American Journal of Cardiology, vol. 173, pp. 128-131 . https://doi.org/10.1016/j.amjcard.2022.02.047
Patients with atrial septal defects (ASDs) have increased mortality and morbidity. This can only partly be explained by hemodynamic changes caused by the ASD, suggesting additional underlying causes. Patients with an ASD have an increased burden of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45881256a6c0828a24c55281b9897538
https://doi.org/10.1016/j.amjcard.2022.02.047
https://doi.org/10.1016/j.amjcard.2022.02.047
Autor:
Menachem Viktor Khamo Sarusie, Cecilia Rönnbäck, Cathrine Jespersgaard, Yeasmeen Ali, Søren Tvorup Christensen, Karen Brøndum-Nielsen, Kjeld Møllgård, Thomas Rosenberg, Lars Allan Larsen, Karen Grønskov
Alexander Disease is a rare leukodystrophy caused by gain-of-function variants in the gene encoding Glial Fibrillary Acidic Protein (GFAP), a major constituent of the intermediate filament of Astrocytes within the central nervous system. Currently, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4817deea9771e28fa67fc6f3bbc37808
https://doi.org/10.1101/2022.11.09.22282105
https://doi.org/10.1101/2022.11.09.22282105
Autor:
Ihsan Bahij, Rikke Hedegaard Dahlrot, Slavka Lukacova, Yasmin Lassen-Ramshad, L. Haldbo-Classen, Aida Muhic, Petra Witt Nyström, C. Rønn Hansen, Lars Allan Larsen, Camilla Skinnerup Byskov, Charlotte Aaquist Haslund, Christian Rønn Hansen, Britta Weber, Trine Lignell Guldberg, Ebbe Laugaard Lorenzen, Jesper F. Kallehauge
Publikováno v:
Radiotherapy and Oncology. 161:S473-S475
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::144148dc80337a572f9c9ad8368b825f
https://doi.org/10.1016/s0167-8140(21)07380-1
https://doi.org/10.1016/s0167-8140(21)07380-1