Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Lars Vatten"'
Autor:
Nigar Sofiyeva, Camilla Krakstad, Mari K. Halle, Tracy A. O'Mara, Pål Romundstad, Kristian Hveem, Lars Vatten, Per E. Lønning, Liv B. Gansmo, Stian Knappskog
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 6659-6667 (2023)
Abstract Background A common 30 kb deletion affecting the APOBEC3A and APOBEC3B genes has been linked to increased APOBEC activity and APOBEC‐related mutational signatures in human cancers. The role of this deletion as a cancer risk factor remains
Externí odkaz:
https://doaj.org/article/4ceaeac0dc614338b1f48747cdc9b398
Autor:
Liv B. Gansmo, Nigar Sofiyeva, Merete Bjørnslett, Pål Romundstad, Kristian Hveem, Lars Vatten, Anne Dørum, Per E. Lønning, Stian Knappskog
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract A germline 29.5-kb deletion variant removes the 3’ end of the APOBEC3A gene and a large part of APOBEC3B, creating a hybrid gene that has been linked to increased APOBEC3 activity and DNA damage in human cancers. We genotyped the APOBEC3A/
Externí odkaz:
https://doaj.org/article/12a41c4868b348eebff763953c5fbf09
Autor:
Nigar Sofiyeva, Camilla Krakstad, Mari K. Halle, Tracy A. O'Mara, Pål Romundstad, Kristian Hveem, Lars Vatten, Per E. Lønning, Liv B. Gansmo, Stian Knappskog
Publikováno v:
Cancer Medicine
Background A common 30 kb deletion affecting the APOBEC3A and APOBEC3B genes has been linked to increased APOBEC activity and APOBEC-related mutational signatures in human cancers. The role of this deletion as a cancer risk factor remains controversi
Autor:
Anthony J. Swerdlow, Dale P. Sandler, Wei Zheng, Anne Zeleniuch-Jacquotte, Alicja Wolk, Walter C. Willett, Elisabete Weiderpass, Kala Visvanathan, Lars Vatten, Antonia Trichopoulou, Rulla M. Tamimi, Malin Sund, Atsuko Sadakane, Thomas E. Rohan, Elio Riboli, Petra H. Peeters, Julie R. Palmer, Kotaro Ozasa, Kim Overvad, Carmen Navarro, Roger L. Milne, Melissa A. Merritt, Huiyan Ma, Eiliv Lund, Susanna C. Larsson, Woon-Puay Koh, Cari M. Kitahara, Victoria A. Kirsh, Timothy J. Key, Rudolf Kaaks, Judy Hoffman-Bolton, Susan E. Hankinson, Inger T. Gram, Graham G. Giles, A. Heather Eliassen, Laure Dossus, Michele M. Doody, Yu Chen, Lesley Butler, Marie-Christine Boutron-Ruault, William J. Blot, Kimberly A. Bertrand, Leslie Bernstein, Laura Baglietto, Claudia Agnoli, Hans-Olov Adami, Michael E. Jones, Kathleen M. McClain, Mark N. Brook, Craig McGowan, Lauren B. Wright, Minouk J. Schoemaker, Hazel B. Nichols
Supplementary table 1: Overview of the number of cohort studies providing information on each type of risk factor in the pooled data set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7620529a985a1f1e179cbb9c0af97629
https://doi.org/10.1158/1055-9965.22436811.v1
https://doi.org/10.1158/1055-9965.22436811.v1
Autor:
Anthony J. Swerdlow, Dale P. Sandler, Wei Zheng, Anne Zeleniuch-Jacquotte, Alicja Wolk, Walter C. Willett, Elisabete Weiderpass, Kala Visvanathan, Lars Vatten, Antonia Trichopoulou, Rulla M. Tamimi, Malin Sund, Atsuko Sadakane, Thomas E. Rohan, Elio Riboli, Petra H. Peeters, Julie R. Palmer, Kotaro Ozasa, Kim Overvad, Carmen Navarro, Roger L. Milne, Melissa A. Merritt, Huiyan Ma, Eiliv Lund, Susanna C. Larsson, Woon-Puay Koh, Cari M. Kitahara, Victoria A. Kirsh, Timothy J. Key, Rudolf Kaaks, Judy Hoffman-Bolton, Susan E. Hankinson, Inger T. Gram, Graham G. Giles, A. Heather Eliassen, Laure Dossus, Michele M. Doody, Yu Chen, Lesley Butler, Marie-Christine Boutron-Ruault, William J. Blot, Kimberly A. Bertrand, Leslie Bernstein, Laura Baglietto, Claudia Agnoli, Hans-Olov Adami, Michael E. Jones, Kathleen M. McClain, Mark N. Brook, Craig McGowan, Lauren B. Wright, Minouk J. Schoemaker, Hazel B. Nichols
Breast cancer is a leading cancer diagnosis among premenopausal women around the world. Unlike rates in postmenopausal women, incidence rates of advanced breast cancer have increased in recent decades for premenopausal women. Progress in identifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afb77bb79d1d6e053c5e4dffb2c8547
https://doi.org/10.1158/1055-9965.c.6515592
https://doi.org/10.1158/1055-9965.c.6515592
Autor:
Eleanor L Watts, Paul N Appleby, Demetrius Albanes, Amanda Black, June M Chan, Chu Chen, Piera M Cirillo, Barbara A Cohn, Michael B Cook, Jenny L Donovan, Luigi Ferrucci, Cedric F Garland, Graham G Giles, Phyllis J Goodman, Laurel A Habel, Christopher A Haiman, Jeff M P Holly, Robert N Hoover, Rudolf Kaaks, Paul Knekt, Laurence N Kolonel, Tatsuhiko Kubo, Loïc Le Marchand, Tapio Luostarinen, Robert J MacInnis, Hanna O Mäenpää, Satu Männistö, E Jeffrey Metter, Roger L Milne, Abraham M Y Nomura, Steven E Oliver, J Kellogg Parsons, Petra H Peeters, Elizabeth A Platz, Elio Riboli, Fulvio Ricceri, Sabina Rinaldi, Harri Rissanen, Norie Sawada, Catherine A Schaefer, Jeannette M Schenk, Frank Z Stanczyk, Meir Stampfer, Pär Stattin, Ulf-Håkan Stenman, Anne Tjønneland, Antonia Trichopoulou, Ian M Thompson, Shoichiro Tsugane, Lars Vatten, Alice S Whittemore, Regina G Ziegler, Naomi E Allen, Timothy J Key, Ruth C Travis
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187741 (2017)
IntroductionSex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis aimed to investigate the associations of anthropometric
Externí odkaz:
https://doaj.org/article/220b20dddc614ed5b5cb7519e7c7fb1c
Autor:
Eleanor L, Watts, Aurora, Perez-Cornago, Georgina K, Fensom, Karl, Smith-Byrne, Urwah, Noor, Colm D, Andrews, Marc J, Gunter, Michael V, Holmes, Richard M, Martin, Konstantinos K, Tsilidis, Demetrius, Albanes, Aurelio, Barricarte, Bas, Bueno-de-Mesquita, Chu, Chen, Barbara A, Cohn, Niki L, Dimou, Luigi, Ferrucci, Leon, Flicker, Neal D, Freedman, Graham G, Giles, Edward L, Giovannucci, Gary E, Goodman, Christopher A, Haiman, Graeme J, Hankey, Jiaqi, Huang, Wen-Yi, Huang, Lauren M, Hurwitz, Rudolf, Kaaks, Paul, Knekt, Tatsuhiko, Kubo, Hilde, Langseth, Gail, Laughlin, Loic, Le Marchand, Tapio, Luostarinen, Robert J, MacInnis, Hanna O, Mäenpää, Satu, Männistö, E Jeffrey, Metter, Kazuya, Mikami, Lorelei A, Mucci, Anja W, Olsen, Kotaro, Ozasa, Domenico, Palli, Kathryn L, Penney, Elizabeth A, Platz, Harri, Rissanen, Norie, Sawada, Jeannette M, Schenk, Pär, Stattin, Akiko, Tamakoshi, Elin, Thysell, Chiaojung Jillian, Tsai, Shoichiro, Tsugane, Lars, Vatten, Elisabete, Weiderpass, Stephanie J, Weinstein, Lynne R, Wilkens, Bu B, Yeap, Naomi E, Allen, Timothy J, Key, Ruth C, Travis
Publikováno v:
Watts, E L, Martin, R M & the PRACTICAL Consortium 2022, ' Circulating free testosterone and risk of aggressive prostate cancer : Prospective and Mendelian randomisation analyses in international consortia ', International Journal of Cancer, vol. 151, no. 7, pp. 1033-1046 . https://doi.org/10.1002/ijc.34116
International Journal of Cancer
Watts, E L, Perez-Cornago, A, Fensom, G K, Smith-Byrne, K, Noor, U, Andrews, C D, Gunter, M J, Holmes, M V, Martin, R M, Tsilidis, K K, Albanes, D, Barricarte, A, Bueno-de-Mesquita, H B, Chen, C, Cohn, B A, Dimou, N L, Ferrucci, L, Flicker, L, Freedman, N D, Giles, G G, Giovannucci, E L, Goodman, G E, Haiman, C A, Hankey, G J, Huang, J, Huang, W-Y, Hurwitz, L M, Kaaks, R, Knekt, P, Kubo, T, Langseth, H, Laughlin, G, Le Marchand, L, Luostarinen, T, MacInnis, R J, Mäenpää, H O, Männistö, S, Metter, E J, Mikami, K, Mucci, L A, Olsen, A W, Ozasa, K, Palli, D, Penney, K L, Platz, E A, Rissanen, H, Sawada, N, Schenk, J M, Stattin, P, PRACTICAL Consortium, CRUK, BPC3, CAPS, PEGASUS & Tamakoshi, A 2022, ' Circulating free testosterone and risk of aggressive prostate cancer : Prospective and Mendelian randomisation analyses in international consortia ', International Journal of Cancer, vol. 151, no. 7, pp. 1033-1046 . https://doi.org/10.1002/ijc.34116
International Journal of Cancer
Watts, E L, Perez-Cornago, A, Fensom, G K, Smith-Byrne, K, Noor, U, Andrews, C D, Gunter, M J, Holmes, M V, Martin, R M, Tsilidis, K K, Albanes, D, Barricarte, A, Bueno-de-Mesquita, H B, Chen, C, Cohn, B A, Dimou, N L, Ferrucci, L, Flicker, L, Freedman, N D, Giles, G G, Giovannucci, E L, Goodman, G E, Haiman, C A, Hankey, G J, Huang, J, Huang, W-Y, Hurwitz, L M, Kaaks, R, Knekt, P, Kubo, T, Langseth, H, Laughlin, G, Le Marchand, L, Luostarinen, T, MacInnis, R J, Mäenpää, H O, Männistö, S, Metter, E J, Mikami, K, Mucci, L A, Olsen, A W, Ozasa, K, Palli, D, Penney, K L, Platz, E A, Rissanen, H, Sawada, N, Schenk, J M, Stattin, P, PRACTICAL Consortium, CRUK, BPC3, CAPS, PEGASUS & Tamakoshi, A 2022, ' Circulating free testosterone and risk of aggressive prostate cancer : Prospective and Mendelian randomisation analyses in international consortia ', International Journal of Cancer, vol. 151, no. 7, pp. 1033-1046 . https://doi.org/10.1002/ijc.34116
Publisher Copyright: © 2022 The Authors. International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC. Previous studies had limited power to assess the associations of testosterone with aggressive disease as a primary endpoin
Autor:
Stian Knappskog, Liv B Gansmo, Pål Romundstad, Merete Bjørnslett, Jone Trovik, Jan Sommerfelt-Pettersen, Erik Løkkevik, Norwegian Breast Cancer Group trial NBCG VI, Rob A E M Tollenaar, Caroline Seynaeve, Peter Devilee, Helga B Salvesen, Anne Dørum, Kristian Hveem, Lars Vatten, Per E Lønning
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36263 (2012)
The MDM2 proto-oncogene plays a key role in central cellular processes like growth control and apoptosis, and the gene locus is frequently amplified in sarcomas. Two polymorphisms located in the MDM2 promoter P2 have been shown to affect cancer risk.
Externí odkaz:
https://doaj.org/article/73927cc6763348dd8815069ae625c8b3
Autor:
Mattias Johansson, Angus Roberts, Dan Chen, Yaoyong Li, Manon Delahaye-Sourdeix, Niraj Aswani, Mark A Greenwood, Simone Benhamou, Pagona Lagiou, Ivana Holcátová, Lorenzo Richiardi, Kristina Kjaerheim, Antonio Agudo, Xavier Castellsagué, Tatiana V Macfarlane, Luigi Barzan, Cristina Canova, Nalin S Thakker, David I Conway, Ariana Znaor, Claire M Healy, Wolfgang Ahrens, David Zaridze, Neonilia Szeszenia-Dabrowska, Jolanta Lissowska, Eleonóra Fabiánová, Ioan Nicolae Mates, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Maria Paula Curado, Sergio Koifman, Ana Menezes, Victor Wünsch-Filho, Jose Eluf-Neto, Paolo Boffetta, Silvia Franceschi, Rolando Herrero, Leticia Fernandez Garrote, Renato Talamini, Stefania Boccia, Pilar Galan, Lars Vatten, Peter Thomson, Diana Zelenika, Mark Lathrop, Graham Byrnes, Hamish Cunningham, Paul Brennan, Jon Wakefield, James D McKay
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36888 (2012)
Genome-wide association studies (GWAS) require large sample sizes to obtain adequate statistical power, but it may be possible to increase the power by incorporating complementary data. In this study we investigated the feasibility of automatically r
Externí odkaz:
https://doaj.org/article/c7c5fa4441ad4f948ef8ff3ff1c14f8c
Autor:
Linn B Strand, Lars E Laugsand, Eli-Anne Skaug, Øyvind Ellingsen, Erik Madssen, Ulrik Wisløff, Lars Vatten, Imre Janszky
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50933 (2012)
BACKGROUND: Insomnia is associated with increased risk of coronary heart disease (CHD), but the underlying mechanisms are not understood. To our knowledge, no previous studies have examined insomnia in relation to endothelial function, an indicator o
Externí odkaz:
https://doaj.org/article/57e64e8cc7c4474e8f99db7e47dfef02