Zobrazeno 1 - 10
of 537
pro vyhledávání: '"Lars‐Olof Wahlund"'
Autor:
Konstantinos Poulakis, Joana B. Pereira, J.-Sebastian Muehlboeck, Lars-Olof Wahlund, Örjan Smedby, Giovanni Volpe, Colin L. Masters, David Ames, Yoshiki Niimi, Takeshi Iwatsubo, Daniel Ferreira, Eric Westman, Japanese Alzheimer’s Disease Neuroimaging Initiative, Australian Imaging, Biomarkers and Lifestyle study
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9a8bf2fda25d4cf28f51b9342acb3be0
Autor:
Atef Badji, Joana Pereira, Sara Shams, Johan Skoog, Anna Marseglia, Konstantinos Poulakis, lina Ryden, Kaj Blennow, Henrik Zetterberg, Silke Kern, Anna Wahlund, Lars-Olof Wahlund, Hélène Girouard, Ingmar Skoog, Eric Westman
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100048- (2024)
Externí odkaz:
https://doaj.org/article/a756af7b1a0a42d19dd41ffbf9d2ed69
Autor:
Caroline Dartora, Anna Marseglia, Gustav Mårtensson, Gull Rukh, Junhua Dang, J-Sebastian Muehlboeck, Lars-Olof Wahlund, Rodrigo Moreno, José Barroso, Daniel Ferreira, Helgi B. Schiöth, Eric Westman, for the Alzheimer’s Disease Neuroimaging Initiative, the Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing, the Japanese Alzheimer’s Disease Neuroimaging Initiative, the AddNeuroMed Consortium
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2024)
IntroductionIn the last few years, several models trying to calculate the biological brain age have been proposed based on structural magnetic resonance imaging scans (T1-weighted MRIs, T1w) using multivariate methods and machine learning. We develop
Externí odkaz:
https://doaj.org/article/07418e3d10c44cdc9c0ff683ec1c29b3
Autor:
Konstantinos Poulakis, Joana B. Pereira, J.-Sebastian Muehlboeck, Lars-Olof Wahlund, Örjan Smedby, Giovanni Volpe, Colin L. Masters, David Ames, Yoshiki Niimi, Takeshi Iwatsubo, Daniel Ferreira, Eric Westman, Japanese Alzheimer’s Disease Neuroimaging Initiative, Australian Imaging, Biomarkers and Lifestyle study
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Understanding Alzheimer’s disease (AD) heterogeneity is important for understanding the underlying pathophysiological mechanisms of AD. However, AD atrophy subtypes may reflect different disease stages or biologically distinct subtypes. He
Externí odkaz:
https://doaj.org/article/df223128c24246949219f1004f621135
Autor:
Carla Abdelnour, Daniel Ferreira, Marleen van de Beek, Nira Cedres, Ketil Oppedal, Lena Cavallin, Frédéric Blanc, Olivier Bousiges, Lars-Olof Wahlund, Andrea Pilotto, Alessandro Padovani, Mercè Boada, Javier Pagonabarraga, Jaime Kulisevsky, Dag Aarsland, Afina W. Lemstra, Eric Westman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Dementia with Lewy bodies (DLB) includes various core clinical features that result in different phenotypes. In addition, Alzheimer’s disease (AD) and cerebrovascular pathologies are common in DLB. All this increases the heterog
Externí odkaz:
https://doaj.org/article/5717a5909e6c4d158531ed13b9b4c902
Autor:
Mana Shams, Sara Shams, Juha Martola, Lena Cavallin, Tobias Granberg, Magnus Kaijser, Max Wintermark, Eric Westman, Peter Aspelin, Maria Kristoffersen Wiberg, Lars-Olof Wahlund
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectiveThe apolipoprotein E (APOE) ε4 allele is the main genetic risk factor for dementia and Alzheimer's disease (AD), but the underlying mechanism for the increased risk is not well understood. Cerebral small vessel disease (SVD) is prevalent am
Externí odkaz:
https://doaj.org/article/cd0d7b7dca5843ffb4bbf279bd6f9387
Autor:
Alejandra Machado, Daniel Ferreira, Michel J. Grothe, Helga Eyjolfsdottir, Per M. Almqvist, Lena Cavallin, Göran Lind, Bengt Linderoth, Åke Seiger, Stefan Teipel, Lars U. Wahlberg, Lars-Olof Wahlund, Eric Westman, Maria Eriksdotter, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background The heterogeneity within Alzheimer’s disease (AD) seriously challenges the development of disease-modifying treatments. We investigated volume of the basal forebrain, hippocampus, and precuneus in atrophy subtypes of AD and expl
Externí odkaz:
https://doaj.org/article/b5872bd41f6149d6b552144d2bd2224f
Autor:
Urban Ekman, Daniel Ferreira, J-Sebastian Muehlboeck, John Wallert, Anna Rennie, Maria Eriksdotter, Lars-Olof Wahlund, Eric Westman
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background There remains a lack of large-scale clinical studies of cognitive impairment that aim to increase diagnostic and prognostic accuracy as well as validate previous research findings. The MemClin project will amass large quantities o
Externí odkaz:
https://doaj.org/article/8ad9716d2de446fa8014972a112b0ef4
Autor:
Atef Badji, Joana B. Pereira, Sara Shams, Johan Skoog, Anna Marseglia, Konstantinos Poulakis, Lina Rydén, Kaj Blennow, Henrik Zetterberg, Silke Kern, Anna Zettergren, Lars-Olof Wahlund, Hélène Girouard, Ingmar Skoog, Eric Westman
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2022)
Background: Hypertension is an important risk factor for Alzheimer’s disease (AD). The pathophysiological mechanisms underlying the relationship between AD and hypertension are not fully understood, but they most likely involve microvascular dysfun
Externí odkaz:
https://doaj.org/article/52ea82fe5fce4b56af5c959aa2c80203
Autor:
Meera Srikrishna, Joana B. Pereira, Rolf A. Heckemann, Giovanni Volpe, Danielle van Westen, Anna Zettergren, Silke Kern, Lars-Olof Wahlund, Eric Westman, Ingmar Skoog, Michael Schöll
Publikováno v:
NeuroImage, Vol 244, Iss , Pp 118606- (2021)
Automatic methods for feature extraction, volumetry, and morphometric analysis in clinical neuroscience typically operate on images obtained with magnetic resonance (MR) imaging equipment. Although CT scans are less expensive to acquire and more wide
Externí odkaz:
https://doaj.org/article/a9651e1db8f44f0b8ff95a6b0c9f637d