Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Lars, Muhl"'
Autor:
Martin Uhrbom, Lars Muhl, Guillem Genové, Jianping Liu, Henrik Palmgren, Ida Alexandersson, Fredrik Karlsson, Alex-Xianghua Zhou, Sandra Lunnerdal, Sonja Gustafsson, Byambajav Buyandelger, Kasparas Petkevicius, Ingela Ahlstedt, Daniel Karlsson, Leif Aasehaug, Liqun He, Marie Jeansson, Christer Betsholtz, Xiao-Rong Peng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Cell identities are defined by intrinsic transcriptional networks and spatio-temporal environmental factors. Here, we explored multiple factors that contribute to the identity of adipose stem cells, including anatomic location, microvascular
Externí odkaz:
https://doaj.org/article/1b79a0f896454151b3ae472ae9fc9feb
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
In this review, the authors look at how recent progress in single-cell transcriptomics complement and enrich the classical, largely morphological, portraits of fibroblasts. The detailed molecular information now available provides new insights into f
Externí odkaz:
https://doaj.org/article/d3a88e121c1940e1938ead5ca617bbf0
Autor:
Manuel Zeitelhofer, Milena Z. Adzemovic, Christine Moessinger, Christina Stefanitsch, Carina Strell, Lars Muhl, Lou Brundin, Linda Fredriksson, Tomas Olsson, Ulf Eriksson, Ingrid Nilsson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Abstract Disruption of blood–brain barrier (BBB) integrity is a feature of various neurological disorders. Here we found that the BBB is differently affected during the preclinical, progression and remission phase of experimental autoimmune encepha
Externí odkaz:
https://doaj.org/article/18f04bdb2bef420e877bfd4a06c159be
Autor:
Lars Muhl, Guillem Genové, Stefanos Leptidis, Jianping Liu, Liqun He, Giuseppe Mocci, Ying Sun, Sonja Gustafsson, Byambajav Buyandelger, Indira V. Chivukula, Åsa Segerstolpe, Elisabeth Raschperger, Emil M. Hansson, Johan L. M. Björkegren, Xiao-Rong Peng, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
To define and distinguish fibroblasts from vascular mural cells have remained challenging. Here, using single-cell RNA sequencing and tissue imaging, the authors provide a molecular basis for cell type classification and reveal inter- and intra-organ
Externí odkaz:
https://doaj.org/article/5f2bea014f994236b4d2abd38b628f2e
Autor:
Guangxia Wang, Lars Muhl, Yvonne Padberg, Laura Dupont, Josi Peterson-Maduro, Martin Stehling, Ferdinand le Noble, Alain Colige, Christer Betsholtz, Stefan Schulte-Merker, Andreas van Impel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
How and where VEGF-C is processed in lymphangiogenesis is unclear. Here, the authors show that development of the zebrafish lymphatic system is locally restricted by Vegfc maturation causing lymphatic sprouting in certain regions, which is regulated
Externí odkaz:
https://doaj.org/article/7d9c7602b7f54a6bbd0b0e6fd9867d83
Autor:
Macarena Fernández-Chacón, Severin Mühleder, Alvaro Regano, Lourdes Garcia-Ortega, Susana F. Rocha, Carlos Torroja, Maria S. Sanchez-Muñoz, Mariya Lytvyn, Verónica Casquero-Garcia, Macarena De Andrés-Laguillo, Lars Muhl, Michael M. Orlich, Konstantin Gaengel, Emilio Camafeita, Jesús Vázquez, Alberto Benguría, M. Luisa Iruela-Arispe, Ana Dopazo, Fátima Sánchez-Cabo, Hannah Carter, Rui Benedito
Publikováno v:
Nature Cardiovascular Research.
Research in R.B.’s laboratory was supported by the European Research Council Starting Grant AngioGenesHD (638028) and Consolidator Grant AngioUnrestUHD (101001814), the CNIC Intramural Grant Program Severo Ochoa (11-2016-IGP-SEV-2015-0505), the Min
Autor:
Lars Muhl, Guillem Genové, Stefanos Leptidis, Jianping Liu, Liqun He, Giuseppe Mocci, Ying Sun, Sonja Gustafsson, Byambajav Buyandelger, Indira V. Chivukula, Åsa Segerstolpe, Elisabeth Raschperger, Emil M. Hansson, Johan L. M. Björkegren, Xiao-Rong Peng, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/83c57908db664426b1e35cc001aef2b7
Autor:
Manuel Zeitelhofer, Hong Li, Milena Z Adzemovic, Ingrid Nilsson, Lars Muhl, Andrew M Scott, Ulf Eriksson
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200649 (2018)
Platelet-derived growth factor CC (PDGF-CC) is important during foetal development but also in pathogenesis of neurologic diseases, cancer and fibrosis. We have previously demonstrated that blocking the PDGF-CC/PDGF receptor alpha (PDGFRα) axis resu
Externí odkaz:
https://doaj.org/article/96212ce54cc943bbaa91ff91a6ed8bea
Autor:
Linda Fredriksson, Milena Z. Adzemovic, Lou Brundin, Tomas Olsson, Carina Strell, Christina Stefanitsch, Manuel Zeitelhofer, Christine Moessinger, Ingrid Nilsson, Lars Muhl, Ulf Eriksson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Scientific Reports
Scientific Reports
Disruption of blood–brain barrier (BBB) integrity is a feature of various neurological disorders. Here we found that the BBB is differently affected during the preclinical, progression and remission phase of experimental autoimmune encephalomyeliti
Autor:
Lars Muhl, Liqun He, Ying Sun, Maarja Andaloussi Mäe, Riikka Pietilä, Jianping Liu, Guillem Genové, Lei Zhang, Yuan Xie, Stefanos Leptidis, Giuseppe Mocci, Simon Stritt, Ahmed Osman, Andrey Anisimov, Karthik Amudhala Hemanthakumar, Markus Räsänen, Emil M. Hansson, Johan Björkegren, Michael Vanlandewijck, Klas Blomgren, Taija Mäkinen, Xiao-Rong Peng, Yizhou Hu, Patrik Ernfors, Thomas D. Arnold, Kari Alitalo, Urban Lendahl, Christer Betsholtz
Humanized mouse models and mouse-adapted SARS-CoV-2 virus are increasingly used to study COVID-19 pathogenesis, so it is impor-tant to learn where the SARS-CoV-2 receptor ACE2 is expressed. Here we mapped ACE2 expression during mouse postnatal develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48773163c4f779200f287930f67ceac5
http://hdl.handle.net/10138/345993
http://hdl.handle.net/10138/345993