Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Lars, Lidgren"'
Autor:
Xinggui Tian, Corina Vater, Deepak Bushan Raina, Lisa Findeisen, Lucas-Maximilian Matuszewski, Magnus Tägil, Lars Lidgren, Anja Winkler, Robert Gottwald, Niels Modler, Klaus-Dieter Schaser, Alexander C. Disch, Stefan Zwingenberger
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 256-271 (2024)
Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been FDA-approved for lumbar fusion, but supraphysiologic initial burst release due to suboptimal carrier and late excess bone resorption caused by osteoclast activation have limited its cl
Externí odkaz:
https://doaj.org/article/eafc253d67d04a97bc38d9b8372e7b77
Autor:
Yang Liu, Tova Corbascio, Jintian Huang, Jacob Engellau, Lars Lidgren, Magnus Tägil, Deepak Bushan Raina
Publikováno v:
Journal of Functional Biomaterials, Vol 15, Iss 8, p 232 (2024)
Osteosarcoma treatment comprises pre-surgical chemotherapy followed by radical surgery and further chemotherapy cycles, but the prognosis has been far from satisfactory. No new drugs or treatment modalities have been developed for clinical use in the
Externí odkaz:
https://doaj.org/article/8c02edb6e55d4f2d867316b0e585357d
Autor:
Sujeesh Sebastian, Felix Tandberg, Yang Liu, Deepak B. Raina, Magnus Tägil, Mattias Collin, Lars Lidgren
Publikováno v:
Bone & Joint Research, Vol 11, Iss 11, Pp 787-802 (2022)
AimsThere is a lack of biomaterial-based carriers for the local delivery of rifampicin (RIF), one of the cornerstone second defence antibiotics for bone infections. RIF is also known for causing rapid development of antibiotic resistance when given a
Externí odkaz:
https://doaj.org/article/f590a324d2eb480f9c0b2108c60bcfab
Autor:
Hong Xu, Yang Liu, Erdem Aras Sezgin, Šarūnas Tarasevičius, Robin Christensen, Deepak Bushan Raina, Magnus Tägil, Lars Lidgren
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Background The treatments for trochanteric fractures try to regain early mobility and limit morbidity and risk of reoperations. The most currently used dynamic hip screw (DHS) and the proximal femoral nail (PFN) are both with pros and cons.
Externí odkaz:
https://doaj.org/article/74ba38d1043d44a5b5be628efdd126f5
Autor:
Yang Liu, Sujeesh Sebastian, Jintian Huang, Tova Corbascio, Jacob Engellau, Lars Lidgren, Magnus Tägil, Deepak Bushan Raina
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Hydroxyapatite (HA) has been widely used as a bone substitute and more recently as a carrier for local delivery of bone targeted drugs. Majority of the approved HA based biomaterials and drug carriers comprise of micrometer sized particulate HA (mHA)
Externí odkaz:
https://doaj.org/article/da99c40b94044855880487775bc63696
Autor:
Sujeesh Sebastian, Erdem Aras Sezgin, Justinas Stučinskas, Šarūnas Tarasevičius, Yang Liu, Deepak Bhushan Raina, Magnus Tägil, Lars Lidgren, Annette W-Dahl
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background The microbiology and the susceptibility patterns of infected total knee arthroplasties (TKAs) vary depending on demographic, local antimicrobial stewardship, and surgical factors. We wanted to compare the recent microbial profile
Externí odkaz:
https://doaj.org/article/6e224c5f456f46d08b203f198fa9f4bb
Autor:
Deepak Bushan Raina, Vetra Markevičiūtė, Mindaugas Stravinskas, Joeri Kok, Ida Jacobson, Yang Liu, Erdem Aras Sezgin, Hanna Isaksson, Stefan Zwingenberger, Magnus Tägil, Šarūnas Tarasevičius, Lars Lidgren
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Pertrochanteric fractures (TF) due to osteoporosis constitute nearly half of all proximal femur fractures. TFs are treated with a surgical approach and fracture fixation is achieved using metallic fixation devices. Poor quality cancellous bone in ost
Externí odkaz:
https://doaj.org/article/a50871f4bf214cc5bcbd80700f58fdf8
Autor:
Yang Liu, Aftab Nadeem, Sujeesh Sebastian, Martin A. Olsson, Sun N. Wai, Emelie Styring, Jacob Engellau, Hanna Isaksson, Magnus Tägil, Lars Lidgren, Deepak Bushan Raina
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100227- (2022)
Efficient systemic pharmacological treatment of solid tumors is hampered by inadequate tumor concentration of cytostatics necessitating development of smart local drug delivery systems. To overcome this, we demonstrate that doxorubicin (DOX), a corne
Externí odkaz:
https://doaj.org/article/7b0a9b1cf962445791667f0747e89548
Autor:
Deepak Bushan Raina, Yang Liu, Otto L. P. Jacobson, K Elizabeth Tanner, Magnus Tägil, Lars Lidgren
Publikováno v:
Bone & Joint Research, Vol 9, Iss 10, Pp 709-718 (2020)
Bone is a dynamic tissue with a quarter of the trabecular and a fifth of the cortical bone being replaced continuously each year in a complex process that continues throughout an individual’s lifetime. Bone has an important role in homeostasis of m
Externí odkaz:
https://doaj.org/article/a3c0b070963444a392db6474232ae725
Autor:
Sujeesh Sebastian, Yang Liu, Robin Christensen, Deepak Bushan Raina, Magnus Tägil, Lars Lidgren
Publikováno v:
Journal of Orthopaedic Translation, Vol 23, Iss , Pp 53-60 (2020)
Background: Prosthetic joint infection (PJI) is the most serious total joint arthroplasty (TJA) complication despite several aseptic and antiseptic preventive measures. There is no clear evidence or even consensus, whether antibiotic-loaded bone ceme
Externí odkaz:
https://doaj.org/article/f80e65f313eb4215a7fcf4a86f3b4ef8