Zobrazeno 1 - 10
of 451
pro vyhledávání: '"Lars, Larsson"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Critical illness myopathy (CIM) detrimentally affects muscle function in ICU patients, with a dramatic loss of muscle mass and function where the loss in specific force exceeds the loss in muscle mass (maximum force normalized to muscle cross-section
Externí odkaz:
https://doaj.org/article/9984c7f9817a41b3ad3e77669060310e
Autor:
Yinglai Huang, Lena Carlsson, Karin Jogeland, Marianne Samuelsson, Lars Larsson, Catarina Jonsborg
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-7 (2023)
Abstract Background Patients with melanoma have been found to be at greater risk of adverse outcomes including mortality after contacting COVID-19. Management of postsurgical complications presented additional challenges by potentially increasing exp
Externí odkaz:
https://doaj.org/article/3c23fd99eaf546d5bd90bd3a8b82ab30
Autor:
Young il Lee, Nicola Cacciani, Ya Wen, Xiang Zhang, Yvette Hedström, Wesley Thompson, Lars Larsson
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1533-1545 (2023)
Abstract Background There is increasing evidence of crosstalk between organs. The neuromuscular junction (NMJ) is a peripheral chemical synapse whose function and morphology are sensitive to acetylcholine (ACh) release and muscle depolarization. In a
Externí odkaz:
https://doaj.org/article/d6001089fb6a44d6b3d587ae4c277905
Autor:
Nicola Cacciani, Åsa Skärlén, Ya Wen, Xiang Zhang, Alex B. Addinsall, Monica Llano‐Diez, Meishan Li, Lennart Gransberg, Yvette Hedström, Bo‐Michael Bellander, David Nelson, Jonas Bergquist, Lars Larsson
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 6, Pp 2669-2682 (2022)
Abstract Background Critical illness myopathy (CIM) is a consequence of modern critical care resulting in general muscle wasting and paralyses of all limb and trunk muscles, resulting in prolonged weaning from the ventilator, intensive care unit (ICU
Externí odkaz:
https://doaj.org/article/f263affcb0e94e709d6974452f755330
Autor:
Alex B. Addinsall, Nicola Cacciani, Anders Backéus, Yvette Hedström, Ganna Shevchenko, Jonas Bergquist, Lars Larsson
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2162-2174 (2022)
Abstract Background Critical illness myopathy (CIM) is a debilitating condition characterized by the preferential loss of the motor protein myosin. CIM is a by‐product of critical care, attributed to impaired recovery, long‐term complications, an
Externí odkaz:
https://doaj.org/article/6352fc59ec1347d78ae38dcf6920c608
Autor:
Sofia Mnuskina, Julian Bauer, Anette Wirth-Hücking, Dominik Schneidereit, Stefanie Nübler, Paul Ritter, Nicola Cacciani, Meishan Li, Lars Larsson, Oliver Friedrich
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Ventilator-induced diaphragm dysfunction (VIDD) is a common sequela of intensive care unit (ICU) treatment requiring mechanical ventilation (MV) and neuromuscular blockade (NMBA). It is characterised by diaphragm weakness, prolonged respirator weanin
Externí odkaz:
https://doaj.org/article/79d709fcaf8a49d58bdb610651053aaf
This publication honours Birgitta Hårdh on her 70th birthday. Birgitta Hårdh is one of the leading experts on European Viking Age, engaged in diverse research projects, and also a vital collaborator in various networks specializing in the period. T
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Background Old age is associated with a significantly increased mortality in COVID-19 patients exposed to long-term controlled mechanical ventilation (CMV) and suggested to be due to the hyperinflammatory response associated with the viral i
Externí odkaz:
https://doaj.org/article/ac24b85a07de42dca70861ea742e249a
Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin
Autor:
Sandra Swist, Andreas Unger, Yong Li, Anja Vöge, Marion von Frieling-Salewsky, Åsa Skärlén, Nicola Cacciani, Thomas Braun, Lars Larsson, Wolfgang A. Linke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Titin is considered an integrator of muscle cell proteins but direct evidence is limited. Here, titin is inactivated in adult mouse muscles, which causes sarcomere disassembly, protein mis-expression and force impairment, recapitulating key alteratio
Externí odkaz:
https://doaj.org/article/302edbcae576463d8910dcb3be630c60
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Critical illness myopathy (CIM) and ventilator-induced diaphragm dysfunction (VIDD) are characterized by severe muscle wasting, muscle paresis, and extubation failure with subsequent increased medical costs and mortality/morbidity rates in intensive
Externí odkaz:
https://doaj.org/article/cb57c6f08a9c4ad286fa32ccca035898