Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Lars, Kunz"'
Autor:
Lars Kunz, Hans Straka
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundEnergetic aspects of neuronal activity have become a major focus of interest given the fact that the brain among all organs dominates the oxygen consumption. At variance with the importance of neuroenergetics, the knowledge about how electr
Externí odkaz:
https://doaj.org/article/cf4b633f63dd41d188cd9bf49c31a91a
Autor:
Suzan Özugur, Myra N. Chávez, Rosario Sanchez-Gonzalez, Lars Kunz, Jörg Nickelsen, Hans Straka
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101250- (2022)
Summary: Oxygen in vertebrates is generally provided through respiratory organs and blood vessels. This protocol describes transcardial injection, vascular distribution, and accumulation of phototrophic microalgae in the brain of Xenopus laevis tadpo
Externí odkaz:
https://doaj.org/article/59d5df0e453249e28d947dd837e4591e
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Neuronal computations related to sensory and motor activity along with the maintenance of spike discharge, synaptic transmission, and associated housekeeping are energetically demanding. The most efficient metabolic process to pro
Externí odkaz:
https://doaj.org/article/1598657a76ea49dcb6236e90515ecf75
Autor:
Suzan Özugur, Myra N. Chávez, Rosario Sanchez-Gonzalez, Lars Kunz, Jörg Nickelsen, Hans Straka
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103158- (2021)
Summary: Neuronal activity in the brain depends on mostly aerobic generation of energy equivalents and thus on a constant O2 supply. Oxygenation of the vertebrate brain has been optimized during evolution by species-specific uptake and transport of O
Externí odkaz:
https://doaj.org/article/a36a63f03f6e493f90b43d5a3d8da07e
Autor:
Konstantin Bagnjuk, Verena Jasmin Kast, Astrid Tiefenbacher, Melanie Kaseder, Toshihiko Yanase, Alexander Burges, Lars Kunz, Doris Mayr, Artur Mayerhofer
Publikováno v:
Journal of Ovarian Research, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract Background Granulosa cell tumors (GCTs) are derived from proliferating granulosa cells of the ovarian follicle. They are known for their late recurrence and most patients with an aggressive form die from their disease. There are no treatment
Externí odkaz:
https://doaj.org/article/de891c5c088440c6b9e8fa449a779fbf
Autor:
Helge Gleiss, Jörg Encke, Andrea Lingner, Todd R Jennings, Sonja Brosel, Lars Kunz, Benedikt Grothe, Michael Pecka
Publikováno v:
PLoS Biology, Vol 17, Iss 7, p e3000150 (2019)
Our sensory environment changes constantly. Accordingly, neural systems continually adapt to the concurrent stimulus statistics to remain sensitive over a wide range of conditions. Such dynamic range adaptation (DRA) is assumed to increase both the e
Externí odkaz:
https://doaj.org/article/2794a500697c45698fcc50fdd6b729df
Autor:
Stefan Keplinger, Barbara Beiderbeck, Stylianos Michalakis, Martin Biel, Benedikt Grothe, Lars Kunz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The Mongolian gerbil (Meriones unguiculatus) is widely used as a model organism for the human auditory system. Its hearing range is very similar to ours and it uses the same mechanisms for sound localization. The auditory circuits underlying these fu
Externí odkaz:
https://doaj.org/article/d553c294bc664330850eaed55d405609
Autor:
Carsten Theo Hack, Theresa Buck, Konstantin Bagnjuk, Katja Eubler, Lars Kunz, Doris Mayr, Artur Mayerhofer
Publikováno v:
Antioxidants, Vol 8, Iss 11, p 518 (2019)
Recent studies showed that KGN cells, derived from a human granulosa cell tumor (GCT), express NADPH oxidase 4 (NOX4), an important source of H2O2. Transient receptor potential melastatin 2 (TRPM2) channel is a Ca2+ permeable cation channel that can
Externí odkaz:
https://doaj.org/article/178f3648638a463d9089de8901590e2c
Autor:
Artur Mayerhofer, Lars Kunz, Manja Luckner, Gerhard Wanner, Florian Flenkenthaler, Georg J. Arnold, Frank M. Köhn, Jan B. Stöckl, Nina Schmid, Thomas Fröhlich, Kim-Gwendolyn Dietrich, J. Ullrich Schwarzer
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
There is evidence for an age-related decline in male reproductive functions, yet how the human testis may age is not understood. Human testicular peritubular cells (HTPCs) transport sperm, contribute to the spermatogonial stem cell (SSC) niche and im
Autor:
Jan B. Stöckl, Konstantin Bagnjuk, Jing Xu, U. Berg, D. Berg, Georg J. Arnold, Thomas Fröhlich, Cecily V. Bishop, Artur Mayerhofer, Rüdiger Behr, Lars Kunz
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-14 (2019)
Cell Death Discovery
Cell Death Discovery
The corpus luteum (CL) is a transient endocrine organ, yet molecular mechanisms resulting in its demise are not well known. The presence of phosphorylated mixed lineage kinase domain-like pseudokinase pMLKL(T357/S358) in human and nonhuman primate CL