Zobrazeno 1 - 10
of 625
pro vyhledávání: '"Lars, Bullinger"'
Autor:
Sophia Gross, Jana Ihlow, Leonie Busack, Kacper Adamiak, Jens Schrezenmeier, Julia Jesse, Michaela Schwarz, Anne Flörcken, Lam Giang Vuong, Kathrin Rieger, Jan Krönke, Philipp le Coutre, Vivien Boldt, Ann-Christin von Brünneck, David Horst, Thomas Burmeister, Igor-Wolfgang Blau, Ulrich Keller, Lars Bullinger, Jörg Westermann
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Therapy-related acute myeloid leukemia (t-AML) often exhibits adverse (genetic) features. There is ongoing discussion on the impact of t-AML on long-term outcome in AML. Therefore, we retrospectively analyzed clinical and biological characte
Externí odkaz:
https://doaj.org/article/23f631a9266149929a52a8ab90a8f749
Autor:
Manuela Krumbholz, Anna Dolnik, Eric Sträng, Tabita Ghete, Sabrina Skambraks, Stephan Hutter, Alfred Simonis, Frank Stegelmann, Meinolf Suttorp, Anselm H.C. Horn, Heinrich Sticht, Torsten Haferlach, Lars Bullinger, Markus Metzler
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Chronic myeloid leukemia (CML) typically occurs in late adulthood. Pediatric CML is a rare form of leukemia. In all age groups, the characteristic genetic driver of the disease is the BCR::ABL1 fusion gene. However, additional genomic events
Externí odkaz:
https://doaj.org/article/c0002c5502d947b59c0f86f299280767
Autor:
Adriane Halik, Marlon Tilgner, Patricia Silva, Natalia Estrada, Robert Altwasser, Ekaterina Jahn, Michael Heuser, Hsin-An Hou, Marta Pratcorona, Robert K. Hills, Klaus H. Metzeler, Laurene Fenwarth, Anna Dolnik, Christine Terre, Klara Kopp, Olga Blau, Martin Szyska, Friederike Christen, Jan Krönke, Loïc Vasseur, Bob Löwenberg, Jordi Esteve, Peter J. M. Valk, Matthieu Duchmann, Wen-Chien Chou, David C. Linch, Hartmut Döhner, Rosemary E. Gale, Konstanze Döhner, Lars Bullinger, Kenichi Yoshida, Frederik Damm
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background Deletions and partial losses of chromosome 7 (chr7) are frequent in acute myeloid leukemia (AML) and are linked to dismal outcome. However, the genomic landscape and prognostic impact of concomitant genetic aberrations remain inco
Externí odkaz:
https://doaj.org/article/c4bde76aa3284c6f887bca011315517d
Autor:
Marta Anna Sobas, Amin T. Turki, Angela Villaverde Ramiro, Alberto Hernández Sánchez, Javier Martinez Elicegui, Teresa González, Raúl Azibeiro Melchor, María Abáigar, Laura Tur, Daniele Dall'Olio, Eric Sträng, Jesse M. Tettero, Gastone Castellani, Axel Benner, Konstanze Döhner, Christian Thiede, Klaus H. Metzeler, Torsten Haferlach, Frederik Damm, Rosa Ayala, Joaquín Martínez-López, Ken I Mills, Jorge Sierra, Sören Lehmann, Matteo G. Della Porta, Jiri Mayer, Dirk Reinhardt, Rubén Villoria Medina, Renate Schulze-Rath, Martje Barbus, Jesús María Hernández-Rivas, Brian J.P Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Since 2017, targeted therapies combined with conventional intensive chemotherapy have started to improve outcome of patients with acute myeloid leukemia (AML). However, even before these innovations outcomes with intensive chemotherapy have improved,
Externí odkaz:
https://doaj.org/article/89bacc8433e84280a3c6e07ffa0f97ee
Autor:
Moritz V. Scharr, Frederik Damm, Paul Krahl, Anna Dieper, Paraskevi D. Veltsista, Alexander Hansch, Marcus Beck, Dominik Gerster, Anna-Chiara Giovannelli, Lars Bullinger, Daniel Zips, Pirus Ghadjar
Publikováno v:
International Journal of Hyperthermia, Vol 41, Iss 1 (2024)
Introduction Hyperthermia (HT) at temperatures between 39 °C and 44 °C is utilized as an adjunctive cancer therapy, serving as potent radio- and chemosensitizer. Its effectiveness in treating solid malignancies has been well established. This raise
Externí odkaz:
https://doaj.org/article/19fb9077debb4ee899831ca550d90dad
Autor:
Frank G. Rücker, Andrea Corbacioglu, Julia Krzykalla, Sibylle Cocciardi, Claudia Lengerke, Ulrich Germing, Gerald Wulf, Maisun A. Samra, Lino L. Teichmann, Michael Lübbert, Michael W. M. Kühn, Martin Bentz, Jörg Westermann, Lars Bullinger, Verena I. Gaidzik, Annika Meid, Sophia Aicher, Frank Stegelmann, Daniela Weber, Anika Schrade, Felicitas Thol, Michael Heuser, Arnold Ganser, Axel Benner, Hartmut Döhner, Konstanze Döhner, for the German‐Austrian Acute Myeloid Leukemia Study Group (AMLSG)
Publikováno v:
HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/57b77f726894460c9984828c82423457
Autor:
Anne Dörr, Insa Vogel, Friedrich Wittenbecher, Jörg Westermann, Peter Thuss-Patience, Johann Ahn, Uwe Pelzer, Juliane Hardt, Lars Bullinger, Anne Flörcken
Publikováno v:
Palliative Care and Social Practice, Vol 18 (2024)
Background: Due to modern therapies, survival in metastatic renal cell carcinoma (mRCC) has been significantly prolonged. Nevertheless, patients suffering from advanced disease often present with severe symptoms. Early integration of palliative care
Externí odkaz:
https://doaj.org/article/83359c14034745fbb1c4ff7cb53a3da0
Autor:
Maximilian Schmutz, Manuela Zucknick, Richard F. Schlenk, Daniel Mertens, Axel Benner, Dieter Weichenhan, Oliver Mücke, Konstanze Döhner, Christoph Plass, Lars Bullinger, Rainer Claus
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Acute myeloid leukemia (AML) is a heterogeneous disease with a poor prognosis. Dysregulation of the epigenetic machinery is a significant contributor to disease development. Some AML patients benefit from treatment with hypomethyl
Externí odkaz:
https://doaj.org/article/97807982449d429dbc05a64bad75bfbb
Autor:
Markus S. Anker, Alessia Lena, Eric J. Roeland, Jan Porthun, Sebastian Schmitz, Sara Hadzibegovic, Philipp Sikorski, Ursula Wilkenshoff, Ann‐Kathrin Fröhlich, Luisa Valentina Ramer, Matthias Rose, Jan Eucker, Tienush Rassaf, Matthias Totzeck, Lorenz H. Lehmann, Stephan vonHaehling, Andrew J.S. Coats, Tim Friede, Javed Butler, Stefan D. Anker, Hanno Riess, Ulf Landmesser, Lars Bullinger, Ulrich Keller, Johann Ahn
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1670-1681 (2023)
Abstract Background Maintaining the ability to perform self‐care is a critical goal in patients with cancer. We assessed whether the patient‐reported ability to walk 4 m and wash oneself predict survival in patients with pre‐terminal cancer. Me
Externí odkaz:
https://doaj.org/article/82004b66f10346b7a6c7d5d527c6beba
Autor:
Sara Hadzibegovic, Jan Porthun, Alessia Lena, Pia Weinländer, Laura C. Lück, Sophia K. Potthoff, Lukas Rösnick, Ann‐Kathrin Fröhlich, Luisa Valentina Ramer, Frederike Sonntag, Ursula Wilkenshoff, Johann Ahn, Ulrich Keller, Lars Bullinger, Amir A. Mahabadi, Matthias Totzeck, Tienush Rassaf, Stephan vonHaehling, Andrew J.S. Coats, Stefan D. Anker, Eric J. Roeland, Ulf Landmesser, Markus S. Anker
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1682-1694 (2023)
Abstract Background Hand grip strength (HGS) is a widely used functional test for the assessment of strength and functional status in patients with cancer, in particular with cancer cachexia. The aim was to prospectively evaluate the prognostic value
Externí odkaz:
https://doaj.org/article/692c182a9e8543e5a40a59b1334c501b