Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Lars, Bode"'
Autor:
Amirthagowri Ambalavanan, Le Chang, Jihoon Choi, Yang Zhang, Sara A. Stickley, Zhi Y. Fang, Kozeta Miliku, Bianca Robertson, Chloe Yonemitsu, Stuart E. Turvey, Piushkumar J. Mandhane, Elinor Simons, Theo J. Moraes, Sonia S. Anand, Guillaume Paré, Janet E. Williams, Brenda M. Murdoch, Gloria E. Otoo, Samwel Mbugua, Elizabeth W. Kamau-Mbuthia, Egidioh W. Kamundia, Debela K. Gindola, Juan M. Rodriguez, Rossina G. Pareja, Daniel W. Sellen, Sophie E. Moore, Andrew M. Prentice, James A. Foster, Linda J. Kvist, Holly L. Neibergs, Mark A. McGuire, Michelle K. McGuire, Courtney L. Meehan, Malcolm R. Sears, Padmaja Subbarao, Meghan B. Azad, Lars Bode, Qingling Duan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Breastfeeding provides many health benefits, but its impact on respiratory health remains unclear. This study addresses the complex and dynamic nature of the mother-milk-infant triad by investigating maternal genomic factors regulating human
Externí odkaz:
https://doaj.org/article/d7c0e875da6b483985a0dffeae48ad19
Autor:
Elizabeth A. Holzhausen, William B. Patterson, Benjamin H. Wong, Sewan Kim, Allison Kupsco, Caitlin G. Howe, Lars Bode, Michael I. Goran, Tanya L. Alderete
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHuman milk contains human milk oligosaccharides (HMOs) and microRNAs (miRNAs), which are key bioactive components. HMOs are indigestible carbohydrates that impact infant growth and development. miRNAs are small, non-coding RNAs that regul
Externí odkaz:
https://doaj.org/article/6da7ea9fc6ba4b4c8d3be1f96603c3e3
Autor:
Chelsey Fiecke, Meghan Crimmins, Ahsan Hameed, Clark Sims, D. Keith Williams, Lars Bode, Audrey Martinez, Aline Andres, Mario G. Ferruzzi
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionMaternal diet modifies profiles of human milk oligosaccharides (HMOs), carotenoids, and polyphenols in human milk (HM). However, substantial variability in profiles exists between women, highlighting the complexity of non-dietary factors
Externí odkaz:
https://doaj.org/article/a0311e2ebc9e40da9d6432c307323257
Autor:
Andrea C. Masi, Lauren C. Beck, John D. Perry, Claire L. Granger, Alice Hiorns, Gregory R. Young, Lars Bode, Nicholas D. Embleton, Janet E. Berrington, Christopher J. Stewart
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101708- (2024)
Summary: Necrotizing enterocolitis (NEC) is a severe intestinal disease of very preterm infants with mother’s own milk (MOM) providing protection, but the contribution of the MOM microbiota to NEC risk has not been explored. Here, we analyze MOM of
Externí odkaz:
https://doaj.org/article/85a2292c84ae45b5b6d2d27016f64093
Autor:
Noopur C. Naik, Elizabeth A. Holzhausen, Bridget N. Chalifour, Maria M. Coffman, Fredrick Lurmann, Michael I. Goran, Lars Bode, Tanya L. Alderete
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Human milk oligosaccharides (HMOs) impact neonate immunity and health outcomes. However, the environmental factors influencing HMO composition remain understudied. This study examined the associations between ambient air pollutant (AAP) expo
Externí odkaz:
https://doaj.org/article/69730130eb6e4fd3be9bb4b9c7f65ecc
Autor:
Martin Becker, Kelsey Fehr, Stephanie Goguen, Kozeta Miliku, Catherine Field, Bianca Robertson, Chloe Yonemitsu, Lars Bode, Elinor Simons, Jean Marshall, Bassel Dawod, Piushkumar Mandhane, Stuart E. Turvey, Theo J. Moraes, Padmaja Subbarao, Natalie Rodriguez, Nima Aghaeepour, Meghan B. Azad
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Links between human milk (HM) and infant development are poorly understood and often focus on individual HM components. Here we apply multi-modal predictive machine learning to study HM and head circumference (a proxy for brain development)
Externí odkaz:
https://doaj.org/article/9786f81a24ce4f3d9160ff7daccc0e85
Autor:
Manoj Gurung, Brent Thomas Schlegel, Dhivyaa Rajasundaram, Renee Fox, Lars Bode, Tianming Yao, Stephen R. Lindemann, Tanya LeRoith, Quentin D. Read, Christy Simecka, Laura Carroll, Aline Andres, Laxmi Yeruva
Publikováno v:
mSystems, Vol 9, Iss 4 (2024)
ABSTRACTMaternal secretor status is one of the determinants of human milk oligosaccharides (HMOs) composition, which, in turn, influences the gut microbiota composition of infants. To understand if this change in gut microbiota impacts immune cell co
Externí odkaz:
https://doaj.org/article/b6528a6056184f3dade4bd8fbb5b9684
Autor:
Clark R. Sims, Jessica L. Saben, Audrey Martinez, Sarah R. Sobik, Meghan R. Crimmins, Jessica E. Bulmanski, Donald Turner, Annalee Furst, Lisa T. Jansen, Lars Bode, Aline Andres
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionMaternal obesity is associated with increased concentrations of human milk (HM) obesogenic hormones, pro-inflammatory cytokines, and oligosaccharides (HMOs) that have been associated with infant growth and adiposity. The objective of this
Externí odkaz:
https://doaj.org/article/a17fe5f8aca24a07be81c889255f3dcf
Autor:
Mirkka Lahdenperä, Laura Galante, Carlos Gonzales-Inca, Jussi Vahtera, Jaana Pentti, Samuli Rautava, Niina Käyhkö, Chloe Yonemitsu, Julia Gupta, Lars Bode, Hanna Lagström
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Increased exposure to greener environments has been suggested to lead to health benefits in children, but the associated mechanisms in early life, particularly via biological mediators such as altered maternal milk composition, remain largel
Externí odkaz:
https://doaj.org/article/6f7a633f770f442ca3d69396d1223175
Autor:
Benjamin P. Kellman, Anne Richelle, Jeong-Yeh Yang, Digantkumar Chapla, Austin W. T. Chiang, Julia A. Najera, Chenguang Liang, Annalee Fürst, Bokan Bao, Natalia Koga, Mahmoud A. Mohammad, Anders Bech Bruntse, Morey W. Haymond, Kelley W. Moremen, Lars Bode, Nathan E. Lewis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Human milk oligosaccharides are fundamental to infant health. Here the authors deploy a multi-omics systems biology approach to elucidate their biosynthetic network, including the associated enzymes and likely structures of ambiguous oligosaccharides
Externí odkaz:
https://doaj.org/article/a121fe2e64dd462990db15ec4c5f9e07