Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Larry W. Robertson"'
Autor:
Francoise A. Gourronc, Brynn K. Helm, Larry W. Robertson, Michael S. Chimenti, Hans-Joachim Lehmler, James A. Ankrum, Aloysius J. Klingelhutz
Publikováno v:
Data in Brief, Vol 45, Iss , Pp 108571- (2022)
Exposure to polychlorinated biphenyls (PCBs) has been associated with the development of metabolic syndrome, a cluster of diseases that includes obesity, diabetes, liver steatosis, and cardiovascular problems. PCBs accumulate and fat and are known to
Externí odkaz:
https://doaj.org/article/5837e6f7caa746c2b61913eaa0bf150a
Autor:
Farrukh Aqil, Hua Shen, Jeyaprakash Jeyabalan, Xing Xin, Hans-Joachim Lehmler, Gabriele Ludewig, Larry W. Robertson, Ramesh C. Gupta
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 820-833 (2014)
A new delivery method via polymeric implants was used for continuous exposure to PCBs. Female Sprague-Dawley rats received subcutaneous polymeric implants containing PCB126 (0.15% load), PCB153 (5% load), or both, for up to 45 d and release kinetics
Externí odkaz:
https://doaj.org/article/e3034141c7cf400a8b0e5a4508bff380
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 9, Pp o2306-o2306 (2010)
The title compound, C14H10Cl4O4S, is a 2,2,2-trichloroethyl-protected precursor of 4′-chlorobiphenyl-3-yl sulfate, a sulfuric acid ester of 4′-chlorobiphenyl-3-ol. The Caromatic—O and O—S bond lengths of the Caromatic—O—S unit are compara
Externí odkaz:
https://doaj.org/article/b524222e45f14947aff1204b506adbd4
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 7, Pp o1615-o1616 (2010)
The four independent molecules in the asymmetric unit of the title compound, C14H9Cl5O4S, are related by pseudo-inversion centres. The molecules have Caromatic—O bond lengths ranging from 1.426 (10) to 1.449 (9) Å and biphenyl-4-yl sulfate ester b
Externí odkaz:
https://doaj.org/article/5a4161c2a9af4ff19b338856cdf4b767
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 5, Pp o1073-o1073 (2010)
The molecular structure of the title compound, C14H11Cl3O4S, displays a biphenyl dihedral angle of 4.9 (2)° between the benzene rings, which is significantly smaller than the calculated dihedral angle of 41.2° of biphenyl derivatives without ortho
Externí odkaz:
https://doaj.org/article/44602bf979d54d6e80049d0c4f6615e1
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 12, Pp o2464-o2464 (2008)
The title compound, C14H10Cl4O4S, is an intermediate in the synthesis of the PCB sulfate monoester of 4′-chloro-biphenyl-4-ol. Both the sulfate monoester and 4′-chloro-biphenyl-4-ol are metabolites of PCB 3 (4-chlorobiphenyl). There are two molec
Externí odkaz:
https://doaj.org/article/ede64cc5301c47d9ae4fe0762ef61a91
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 2, Pp o424-o424 (2008)
The methoxy group of the title compound, C7H5Cl3O, is rotated out of the plane of the aromatic ring system, with a dihedral angle of 84.11 (13)°, due to the two bulky ortho-chloro substituents.
Externí odkaz:
https://doaj.org/article/c9699365ba4848f1adba006c348e3ef0
Autor:
Larry W. Robertson, Isabelle Berberian, Tim Borges, Li-Chuan Chen, Ching K. Chow, Howard P. Glauert, Johannes G. Filser, Helmut Thomas
Publikováno v:
PPAR Research, Vol 2007 (2007)
The purpose of this study was to determine the effects of PCBs and PBBs on peroxisome proliferator-activated receptor-α-(PPARα-) associated enzyme activities or protein levels. Male Sprague-Dawley rats were administered a single IP injection (150
Externí odkaz:
https://doaj.org/article/d3fccd4365ea4b36bc2e77f039e2299c
Autor:
Gopi S. Gadupudi, James Watt, Casey F. Pulliam, Martin J. J. Ronis, Ashlee E Williams, Alexander W. Alund, Larry W. Robertson, Ezazul Haque
Publikováno v:
Arch Toxicol
Skeletal toxicity has been reported following exposure to polychlorinated biphenyl (PCB) mixtures. However, molecular mechanisms remain poorly understood. We exposed groups of male 4–5-week-old Sprague–Dawley rats to 3,3′, 4, 4′, 5-pentachlor
Publikováno v:
Environ Sci Pollut Res Int
Subcutaneous white adipose tissue is capable of becoming thermogenic in a process that is referred to as "beiging." Beiging is associated with activation of the uncoupling protein, UCP1, and is known to be important for preventing adipose hypertrophy