Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Larry W Tjoelker"'
Autor:
Munehisa Yabuki, W Jason Cummings, John B Leppard, Robert M Immormino, Christi L Wood, Daniel S Allison, Patrick W Gray, Larry W Tjoelker, Nancy Maizels
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36032 (2012)
Monoclonal antibodies (mAbs) can be potent and highly specific therapeutics, diagnostics and research reagents. Nonetheless, mAb discovery using current in vivo or in vitro approaches can be costly and time-consuming, with no guarantee of success. We
Externí odkaz:
https://doaj.org/article/a23b053ae13444a0a46f729efdb2b925
Autor:
Gopal K. Marathe, Adriana Ribeiro Silva, Hugo Caire de Castro Faria Neto, Larry W. Tjoelker, Stephen M. Prescott, Guy A. Zimmerman, Thomas M. McIntyre
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 9, Pp 1430-1437 (2001)
Lysophosphatidylcholine is an abundant component of plasma and oxidized LDL that displays several biological activities, some of which may occur through the platelet-activating factor (PAF) receptor. We find that commercial lysophosphatidylcholine, i
Externí odkaz:
https://doaj.org/article/7f06267456a84057b816920aa5b5d5fa
Autor:
Gopal K. Marathe, Kathleen A. Harrison, L. Jackson Roberts, II, Jason D. Morrow, Robert C. Murphy, Larry W. Tjoelker, Stephen M. Prescott, Guy A. Zimmerman, Thomas M. McIntyre
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 587-596 (2001)
Unmitigated oxidative stress is deleterious, as epitomized by CCl4 intoxication. In this well-characterized model of free radical-initiated damage, liver metabolism of CCl4 to CCl3. causes lipid peroxidation, F-ring isoprostane formation, and patholo
Externí odkaz:
https://doaj.org/article/782ebb3db6c541f2b370e6269796dade
Autor:
Nicholas J. Lynch, Peter W. Andrew, Christi L. Wood, Robert B. Sim, W. Jason Cummings, Peter Garred, Teizo Fujita, Wilhelm J. Schwaeble, Gregory A. Demopulos, Sadam Yaseen, Steven H. Sacks, Munehisa Yabuki, Larry W. Tjoelker, Russell Wallis, Peter J. Lachmann, Thomas Dudler
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(5)
All 3 activation pathways of complement-the classic pathway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central event: the cleavage and activation of the abundant third complement component, C3, via formation of
Autor:
Emily S Liebeskind, Wei-Jun Qian, Richard D. Smith, William J. Ellis, Lawrence D. True, Chung Ying Huang, Hui Zhang, Peter S. Nelson, Jong-Seo Kim, Priska D. von Haller, Alvin Y. Liu, Mingliang Ye, Larry W. Tjoelker
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
A by-product in the processing of prostate tissue for cell sorting by collagenase digestion is the media supernatant that remains after the cells are harvested. These supernatants contain proteins made by the cells within the tissue. Quantitative pro
Autor:
Adriana R. Silva, Stephen M. Prescott, Hugo Caire de Castro Faria Neto, Gopal K. Marathe, Guy A. Zimmerman, Thomas M. McIntyre, Larry W. Tjoelker
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 9, Pp 1430-1437 (2001)
Lysophosphatidylcholine is an abundant component of plasma and oxidized LDL that displays several biological activities, some of which may occur through the platelet-activating factor (PAF) receptor. We find that commercial lysophosphatidylcholine, i
Autor:
Giuseppe A. Andres, Mariarosaria Boccellino, Pier Giulio Conaldi, Giovanni Camussi, Luigi Biancone, Larry W. Tjoelker, David M. Stern, Edward Cantu, Giuseppe Paolo Segoloni, Shoici Maruyama, Vincenzo Cantaluppi, Lorenzo Del Sorbo
Publikováno v:
Transplantation. 70:1198-1205
BACKGROUND Platelet-activating factor (PAF) is a phospholipid mediator of inflammation which has been implicated in rejection. The interaction of anti-alpha-galactosyl natural antibodies (anti-alpha gal Abs) with endothelial cells is the initial step
Autor:
Stephen M. Prescott, Sally P.A. McCormick, Stephen G. Young, Thomas M. McIntyre, Darius Vaitkus, Patrick W. Gray, Larry W. Tjoelker, Diana M. Stafforini
Publikováno v:
Journal of Biological Chemistry. 274:7018-7024
The platelet-activating factor acetylhydrolases are enzymes that were initially characterized by their ability to hydrolyze platelet-activating factor (PAF). In human plasma, PAF acetylhydrolase (EC 3.1.1.47) circulates in a complex with low density
Autor:
K A Dzenko, Stephen Dewhurst, Yusuf A. Hannun, Seth W. Perry, Ghassan Dbaibo, J A Hamilton, J S Whittaker, Larry W. Tjoelker, Leon G. Epstein, Harris A. Gelbard
Publikováno v:
Journal of Biological Chemistry. 273:17660-17664
Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system results in neuronal apoptosis. Activated HIV-1-infected monocytes secrete high levels of the proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) and the
Autor:
Vicki L. Schweickart, Heather Brammer, Ronald Godiska, Christi L. Wood, Anthony J. Demaggio, David Chantry, Carol J. Raport, Kim Walton, Johnny T. Stine, Aaron Smith, Larry W. Tjoelker, Angela Epp, Patrick W. Gray
Publikováno v:
Journal of Leukocyte Biology. 64:49-54
High throughput partial sequencing of randomly selected cDNA clones has proven to be a powerful tool for examining the relative abundance of mRNAs and for the identification of novel gene products. Because of the important role played by macrophages