Zobrazeno 1 - 10
of 1 287
pro vyhledávání: '"Larry W Moreland"'
Autor:
Irena Doubelt, Jason M Springer, Tanaz A Kermani, Antoine G Sreih, Cristina Burroughs, David Cuthbertson, Simon Carette, Nader A Khalidi, Curry L Koening, Carol Langford, Carol A McAlear, Larry W Moreland, Paul A Monach, Dianne G Shaw, Philip Seo, Ulrich Specks, Kenneth J Warrington, Kalen Young, Peter A Merkel, Christian Pagnoux
Publikováno v:
Interactive Journal of Medical Research, Vol 11, Iss 1, p e27273 (2022)
BackgroundPatient-based registries can help advance research on rare diseases such as eosinophilic granulomatosis with polyangiitis (EGPA), a complex multiorgan form of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. ObjectiveThe
Externí odkaz:
https://doaj.org/article/56119628cf6c4a39a62f8ed95e17f3cc
Autor:
Jason Ptacek, Rachael E Hawtin, Dongmei Sun, Brent Louie, Erik Evensen, Barbara B Mittleman, Alessandra Cesano, Guy Cavet, Clifton O Bingham, Stacey S Cofield, Jeffrey R Curtis, Maria I Danila, Chander Raman, Richard A Furie, Mark C Genovese, William H Robinson, Marc C Levesque, Larry W Moreland, Peter A Nigrovic, Nancy A Shadick, James R O'Dell, Geoffrey M Thiele, E William St Clair, Christopher C Striebich, Matthew B Hale, Houman Khalili, Franak Batliwalla, Cynthia Aranow, Meggan Mackay, Betty Diamond, Garry P Nolan, Peter K Gregersen, S Louis Bridges
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244187 (2021)
Rheumatoid arthritis (RA) is a systemic and incurable autoimmune disease characterized by chronic inflammation in synovial lining of joints. To identify the signaling pathways involved in RA, its disease activity, and treatment response, we adapted a
Externí odkaz:
https://doaj.org/article/9b1ea73e854343108c3cc3ca29f2e25a
Autor:
Rennie L Rhee, Cecile T J Holweg, Kit Wong, David Cuthbertson, Simon Carette, Nader A Khalidi, Curry L Koening, Carol A Langford, Carol A McAlear, Paul A Monach, Larry W Moreland, Christian Pagnoux, Philip Seo, Ulrich Specks, Antoine G Sreih, Steven R Ytterberg, Peter A Merkel, Vasculitis Clinical Research Consortium
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205768 (2018)
OBJECTIVE:Identification of a biomarker for disease activity in eosinophilic granulomatosis with polyangiitis (EGPA; Churg-Strauss) remains an unmet need. This study examined the value of serum periostin, a marker of type 2 inflammation, as a measure
Externí odkaz:
https://doaj.org/article/5033a7268f404b9498d249f71033979a
Autor:
Aarat M Patel, Larry W Moreland
Publikováno v:
Drug Design, Development and Therapy, Vol 2010, Iss default, Pp 263-278 (2010)
Aarat M Patel1,2, Larry W Moreland11Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA; 2Division of Pediatric Rheumatology, Children’s Hospital of Pittsburgh, Pittsburgh, PA, USAAbstract: The dawn of th
Externí odkaz:
https://doaj.org/article/5cf15498bd33406494309a0f4a4d4239
Autor:
Yukinori Okada, Dorothee Diogo, Jeffrey D Greenberg, Faten Mouassess, Walid A L Achkar, Robert S Fulton, Joshua C Denny, Namrata Gupta, Daniel Mirel, Stacy Gabriel, Gang Li, Joel M Kremer, Dimitrios A Pappas, Robert J Carroll, Anne E Eyler, Gosia Trynka, Eli A Stahl, Jing Cui, Richa Saxena, Marieke J H Coenen, Henk-Jan Guchelaar, Tom W J Huizinga, Philippe Dieudé, Xavier Mariette, Anne Barton, Helena Canhão, João E Fonseca, Niek de Vries, Paul P Tak, Larry W Moreland, S Louis Bridges, Corinne Miceli-Richard, Hyon K Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, Towfique Raj, Philip L De Jager, Soumya Raychaudhuri, Jane Worthington, Leonid Padyukov, Lars Klareskog, Katherine A Siminovitch, Peter K Gregersen, Elaine R Mardis, Thurayya Arayssi, Layla A Kazkaz, Robert M Plenge
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87645 (2014)
Integrating genetic data from families with highly penetrant forms of disease together with genetic data from outbred populations represents a promising strategy to uncover the complete frequency spectrum of risk alleles for complex traits such as rh
Externí odkaz:
https://doaj.org/article/2190887409354955965ee70f47ab4ea7
Autor:
Jing Cui, Eli A Stahl, Saedis Saevarsdottir, Corinne Miceli, Dorothee Diogo, Gosia Trynka, Towfique Raj, Maša Umiċeviċ Mirkov, Helena Canhao, Katsunori Ikari, Chikashi Terao, Yukinori Okada, Sara Wedrén, Johan Askling, Hisashi Yamanaka, Shigeki Momohara, Atsuo Taniguchi, Koichiro Ohmura, Fumihiko Matsuda, Tsuneyo Mimori, Namrata Gupta, Manik Kuchroo, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Marieke Herenius, Marieke E Doorenspleet, Paul-Peter Tak, J Bart A Crusius, Irene E van der Horst-Bruinsma, Gert Jan Wolbink, Piet L C M van Riel, Mart van de Laar, Henk-Jan Guchelaar, Nancy A Shadick, Cornelia F Allaart, Tom W J Huizinga, Rene E M Toes, Robert P Kimberly, S Louis Bridges, Lindsey A Criswell, Larry W Moreland, João Eurico Fonseca, Niek de Vries, Barbara E Stranger, Philip L De Jager, Soumya Raychaudhuri, Michael E Weinblatt, Peter K Gregersen, Xavier Mariette, Anne Barton, Leonid Padyukov, Marieke J H Coenen, Elizabeth W Karlson, Robert M Plenge
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003394 (2013)
Anti-tumor necrosis factor alpha (anti-TNF) biologic therapy is a widely used treatment for rheumatoid arthritis (RA). It is unknown why some RA patients fail to respond adequately to anti-TNF therapy, which limits the development of clinical biomark
Externí odkaz:
https://doaj.org/article/81c1f31b39334e34b1f84c06c37997b4
Autor:
James M Kelley, Laura B Hughes, Jeffrey D Faggard, Maria I Danila, Monica H Crawford, Yuanqing Edberg, Miguel A Padilla, Hemant K Tiwari, Andrew O Westfall, Graciela S Alarcón, Doyt L Conn, Beth L Jonas, Leigh F Callahan, Edwin A Smith, Richard D Brasington, David B Allison, Robert P Kimberly, Larry W Moreland, Jeffrey C Edberg, S Louis Bridges
Publikováno v:
PLoS Genetics, Vol 5, Iss 12 (2009)
Externí odkaz:
https://doaj.org/article/3bb0aeb21193469a84f1ded7e015395d
Autor:
James M Kelley, Laura B Hughes, Jeffrey D Faggard, Maria I Danila, Monica H Crawford, Yuanqing Edberg, Miguel A Padilla, Hemant K Tiwari, Andrew O Westfall, Graciela S Alarcón, Doyt L Conn, Beth L Jonas, Leigh F Callahan, Edwin A Smith, Richard D Brasington, David B Allison, Robert P Kimberly, Larry W Moreland, Jeffrey C Edberg, S Louis Bridges
Publikováno v:
PLoS Genetics, Vol 5, Iss 3, p e1000424 (2009)
Cytotoxic T-lymphocyte associated protein 4 (CTLA4) is a negative regulator of T-cell proliferation. Polymorphisms in CTLA4 have been inconsistently associated with susceptibility to rheumatoid arthritis (RA) in populations of European ancestry but h
Externí odkaz:
https://doaj.org/article/750a2b5d380e4bf59fa98a6bbe662f52
Autor:
Bryant R. England, Benjamin J. Smith, Nancy A. Baker, Jennifer L. Barton, Carol A. Oatis, Gordon Guyatt, Allen Anandarajah, Kristine Carandang, Karmela Kim Chan, Deb Constien, Eileen Davidson, Carole V. Dodge, Anita Bemis‐Dougherty, Sotiria Everett, Nadine Fisher, Liana Fraenkel, Susan M. Goodman, Janet Lewis, Victoria Menzies, Larry W. Moreland, Iris Navarro‐Millan, Sarah Patterson, Lawrence 'Rick' Phillips, Neha Shah, Namrata Singh, Daniel White, Rawan AlHeresh, Kamil E. Barbour, Thomas Bye, Dana Guglielmo, Rebecca Haberman, Tate Johnson, Anatole Kleiner, Chris Y. Lane, Linda C. Li, Hiral Master, Daniel Pinto, Janet L. Poole, Kimberly Steinbarger, Daniel Sztubinski, Louise Thoma, Vlad Tsaltskan, Marat Turgunbaev, Courtney Wells, Amy S. Turner, Jonathan R. Treadwell
Publikováno v:
Arthritis & Rheumatology.
Autor:
Christian Pagnoux, Antoine G. Sreih, David Cuthbertson, Curry L. Koening, Simon Carette, Kenneth J. Warrington, Nader Khalidi, Tanaz A. Kermani, Peter A. Merkel, Ulrich Specks, Larry W. Moreland, Philip Seo, Carol A. Langford, Carol A. McAlear, Paul A. Monach
Publikováno v:
Rheumatology (Oxford)
Objective To study the prevalence, risk and clinical associations of hypothyroidism among several forms of vasculitis. Methods Patients with GCA, Takayasu’s arteritis (TAK), PAN and the three forms of ANCA-associated vasculitis [AAV; granulomatosis