Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Larry W Johnson"'
Autor:
Anil K Challa, Evan R Boitet, Ashley N Turner, Larry W Johnson, Daniel Kennedy, Ethan R Downs, Katherine M Hymel, Alecia K Gross, Robert A Kesterson
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155812 (2016)
Tyrosinase is a key enzyme in melanin biosynthesis. Mutations in the gene encoding tyrosinase (Tyr) cause oculocutaneous albinism (OCA1) in humans. Alleles of the Tyr gene have been useful in studying pigment biology and coat color formation. Over 10
Externí odkaz:
https://doaj.org/article/95612f7154c0442c904d4ddc71281093
Publikováno v:
Bio-protocol. 7(16)
Rat embryo transfer surgeries are becoming more common with targeted nucleases increasing the demand for rat models. This protocol details pre-surgical preparation, improved surgical techniques for placing embryos into the oviduct, and post-surgical
Autor:
Scott W. Ballinger, Robert A. Kesterson, Larry W. Johnson, Danny R. Welch, David G. Westbrook, Kyle P. Feeley, Alexander W. Bray
Publikováno v:
Cancer Research. 75:4429-4436
Current paradigms of carcinogenic risk suggest that genetic, hormonal, and environmental factors influence an individual's predilection for developing metastatic breast cancer. Investigations of tumor latency and metastasis in mice have illustrated d
Autor:
Louis J. Dell'Italia, Jessica L. Fetterman, Douglas R. Moellering, Chih-Chang Wei, Wayne E. Bradley, Scott W. Ballinger, Victor M. Darley-Usmar, Melissa J Sammy, Jinju Zhang, Danny R. Welch, Blake R. Zelickson, Balu K. Chacko, Xuemei Cao, Larry W. Johnson, Kimberly J. Dunham-Snary, Michelle S. Johnson, Robert A. Kesterson, Melissa Pompilius, David G. Westbrook, Theodore G. Schurr
Publikováno v:
Biochemical Journal. 455:157-167
Dysfunctional bioenergetics has emerged as a key feature in many chronic pathologies such as diabetes and cardiovascular disease. This has led to the mitochondrial paradigm in which it has been proposed that mitochondrial DNA (mtDNA) sequence variati
Autor:
Katherine M. Hymel, Anil K. Challa, Ethan R. Downs, Daniel Kennedy, Ashley N. Turner, Alecia K. Gross, Evan R. Boitet, Robert A. Kesterson, Larry W. Johnson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0155812 (2016)
PLoS ONE, Vol 11, Iss 5, p e0155812 (2016)
Tyrosinase is a key enzyme in melanin biosynthesis. Mutations in the gene encoding tyrosinase (Tyr) cause oculocutaneous albinism (OCA1) in humans. Alleles of the Tyr gene have been useful in studying pigment biology and coat color formation. Over 10
Autor:
Danny R. Welch, Scott W. Ballinger, Robert A. Kesterson, Jay L. Vivian, Laura J. Lambert, Larry W. Johnson
Publikováno v:
BIO-PROTOCOL. 6
The mitochondrial paradigm for common disease proposes that mitochondrial DNA (mtDNA) sequence variation can contribute to disease susceptibility and progression. To test this concept, we developed the Mitochondrial-nuclear eXchange (MNX) model, in w
Autor:
Larry W. Johnson
Publikováno v:
Nurse Leader. 2:50-53
After almost 43 years on this planet, I can truly say that my life has been blessed. There are lots of ways that is evident, but one that I didn't fully appreciate until last year was the fact that I have been blissfully absent from hospitals.
Autor:
Satoshi Akagi, Anna V. Anagnostopoulos, Benjamin P. Beaton, Cory F. Brayton, Steve Brown, Anthony W.S. Chan, Tom Doetschman, Rex A. Dunham, David A. Dunn, Janan T. Eppig, Almudena Fernández, Tatiana Flisikowska, Vasiliy Galat, Robert A. Godke, Philip Iannaccone, Michael H. Irwin, Larry W. Johnson, Yoko Kato, Teoan Kim, Alexander Kind, Bon Chul Koo, Mo Sun Kwon, Daniel J. Ledbetter, Michael J. Martin, Kazutsugu Matsukawa, Colin McKerlie, Lluís Montoliu, Paul E. Mozdziak, Akira Onishi, Paul A. Overbeek, James N. Petitte, L. Philip Sanford, Jorge A. Piedrahita, Carl A. Pinkert, Wendy K. Pogozelski, H. Greg Polites, Edmund B. Rucker, Marina Sansinena, Angelika Schnieke, Kumiko Takeda, James A. Thomson, Ian A. Trounce, Yukio Tsunoda, Cristina Vicente-García, Kevin D. Wells, Richard N. Winn, Curtis R. Youngs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9027b459b29bc3a69e670b1abb3c19eb
https://doi.org/10.1016/b978-0-12-410490-7.00030-x
https://doi.org/10.1016/b978-0-12-410490-7.00030-x
Beginning with DNA microinjection, this chapter reviews techniques and instrumentation associated with transgenic animal production, animal husbandry, and related equipment and instrumentation. While relative efficiencies are debated and new methodol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8de4cd5c0c595d51d2f1c65d8e888db
https://doi.org/10.1016/b978-0-12-410490-7.00002-5
https://doi.org/10.1016/b978-0-12-410490-7.00002-5
Publikováno v:
Transgenic Research. 8:119-123
At present, there are no means for creation of relevant animal models of human mitochondrial DNA (mtDNA)-based diseases in a directed fashion. As an initial step towards this end, we have developed a microinjection technique for transfer of isolated,