Zobrazeno 1 - 10
of 1 287
pro vyhledávání: '"Larry W, Moreland"'
Autor:
Garrett Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Vivian P. Bykerk, Laura T. Donlin, Susan M. Goodman, Gary S. Firestein, David L. Boyle, V. Michael Holers, Larry W. Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B. Brenner, Juilee Thakar, Andrew McDavid, Deepak A. Rao, Jennifer H. Anolik
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease involving antigen-specific T and B cells. Here, we perform single-cell RNA and repertoire sequencing on paired synovial tissue and blood samples from 12 seropositive RA patients. We identify
Externí odkaz:
https://doaj.org/article/b76b85a9921847d4919133eeb47ed023
Publikováno v:
BMC Rheumatology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Background This study aimed to assess the association between social factors, demographic parameters, and disease activity among rheumatoid arthritis (RA) patients. Methods The University of Pittsburgh Rheumatoid Arthritis Comparative Effect
Externí odkaz:
https://doaj.org/article/db8b233a309e4ed48ab8daa5b053b354
Autor:
V. Michael Holers, Rachel M. Frank, Andrew Clauw, Jennifer Seifert, Michael Zuscik, Sakthi Asokan, Christopher Striebich, Michael R. Clay, Larry W. Moreland, Nirmal K. Banda
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Anterior cruciate ligament (ACL) injury and meniscal tear (MT) are major causal factors for developing post-traumatic osteoarthritis (PTOA), but the biological mechanism(s) are uncertain. After these structural damages, the synovium could be affected
Externí odkaz:
https://doaj.org/article/00b8aa3de9c0458f9f8dd0451e8d1d61
Autor:
Despina Michailidou, Bhargavi Duvvuri, Runa Kuley, David Cuthbertson, Peter C. Grayson, Nader A. Khalidi, Curry L. Koening, Carol A. Langford, Carol A. McAlear, Larry W. Moreland, Christian Pagnoux, Philip Seo, Ulrich Specks, Antoine G. Sreih, Kenneth J. Warrington, Tomas Mustelin, Paul A. Monach, Peter A. Merkel, Christian Lood
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-10 (2022)
Abstract Objective To assess markers of neutrophil activation such as calprotectin and N-formyl methionine (fMET) in anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) and large-vessel vasculitis (LVV). Methods Levels of fMET, and c
Externí odkaz:
https://doaj.org/article/4d4ff93e6b7146b1804cbd57bf2f0bc4
Autor:
Irena Doubelt, David Cuthbertson, Simon Carette, Sharon A. Chung, Lindsy J. Forbess, Nader A. Khalidi, Curry L. Koening, Carol Langford, Carol A. McAlear, Larry W. Moreland, Paul A. Monach, Philip Seo, Ulrich Specks, Robert F. Spiera, Jason M. Springer, Antoine G. Sreih, Kenneth J. Warrington, Peter A. Merkel, Christian Pagnoux, the Vasculitis Clinical Research Consortium
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 6, Pp 404-412 (2021)
Objective To describe clinical manifestations and outcomes in patients with eosinophilic granulomatosis with polyangiitis (EGPA) in North America. Methods Analysis of patients aged 18 years or older who fulfilled the 1990 American College of Rheumato
Externí odkaz:
https://doaj.org/article/82128a1fdc6e4dcaa4108c0e269815ce
Autor:
Irena Doubelt, Jason M Springer, Tanaz A Kermani, Antoine G Sreih, Cristina Burroughs, David Cuthbertson, Simon Carette, Nader A Khalidi, Curry L Koening, Carol Langford, Carol A McAlear, Larry W Moreland, Paul A Monach, Dianne G Shaw, Philip Seo, Ulrich Specks, Kenneth J Warrington, Kalen Young, Peter A Merkel, Christian Pagnoux
Publikováno v:
Interactive Journal of Medical Research, Vol 11, Iss 1, p e27273 (2022)
BackgroundPatient-based registries can help advance research on rare diseases such as eosinophilic granulomatosis with polyangiitis (EGPA), a complex multiorgan form of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. ObjectiveThe
Externí odkaz:
https://doaj.org/article/56119628cf6c4a39a62f8ed95e17f3cc
Autor:
Jason Ptacek, Rachael E Hawtin, Dongmei Sun, Brent Louie, Erik Evensen, Barbara B Mittleman, Alessandra Cesano, Guy Cavet, Clifton O Bingham, Stacey S Cofield, Jeffrey R Curtis, Maria I Danila, Chander Raman, Richard A Furie, Mark C Genovese, William H Robinson, Marc C Levesque, Larry W Moreland, Peter A Nigrovic, Nancy A Shadick, James R O'Dell, Geoffrey M Thiele, E William St Clair, Christopher C Striebich, Matthew B Hale, Houman Khalili, Franak Batliwalla, Cynthia Aranow, Meggan Mackay, Betty Diamond, Garry P Nolan, Peter K Gregersen, S Louis Bridges
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244187 (2021)
Rheumatoid arthritis (RA) is a systemic and incurable autoimmune disease characterized by chronic inflammation in synovial lining of joints. To identify the signaling pathways involved in RA, its disease activity, and treatment response, we adapted a
Externí odkaz:
https://doaj.org/article/9b1ea73e854343108c3cc3ca29f2e25a
Autor:
Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure, Shuqiang Li, Edward P. Browne, Adam Chicoine, Danielle Sutherby, Akiko Noma, Accelerating Medicines Partnership RA/SLE Network, Chad Nusbaum, Stephen Kelly, Alessandra B. Pernis, Lionel B. Ivashkiv, Susan M. Goodman, William H. Robinson, Paul J. Utz, James A. Lederer, Ellen M. Gravallese, Brendan F. Boyce, Nir Hacohen, Costantino Pitzalis, Peter K. Gregersen, Gary S. Firestein, Soumya Raychaudhuri, Larry W. Moreland, V. Michael Holers, Vivian P. Bykerk, Andrew Filer, David L. Boyle, Michael B. Brenner, Jennifer H. Anolik
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-15 (2018)
Abstract Background Detailed molecular analyses of cells from rheumatoid arthritis (RA) synovium hold promise in identifying cellular phenotypes that drive tissue pathology and joint damage. The Accelerating Medicines Partnership RA/SLE Network aims
Externí odkaz:
https://doaj.org/article/f1834e16a4ee4cddb44b1feb039eb118
Autor:
Bryant R. England, Benjamin J. Smith, Nancy A. Baker, Jennifer L. Barton, Carol A. Oatis, Gordon Guyatt, Allen Anandarajah, Kristine Carandang, Karmela Kim Chan, Deb Constien, Eileen Davidson, Carole V. Dodge, Anita Bemis‐Dougherty, Sotiria Everett, Nadine Fisher, Liana Fraenkel, Susan M. Goodman, Janet Lewis, Victoria Menzies, Larry W. Moreland, Iris Navarro‐Millan, Sarah Patterson, Lawrence 'Rick' Phillips, Neha Shah, Namrata Singh, Daniel White, Rawan AlHeresh, Kamil E. Barbour, Thomas Bye, Dana Guglielmo, Rebecca Haberman, Tate Johnson, Anatole Kleiner, Chris Y. Lane, Linda C. Li, Hiral Master, Daniel Pinto, Janet L. Poole, Kimberly Steinbarger, Daniel Sztubinski, Louise Thoma, Vlad Tsaltskan, Marat Turgunbaev, Courtney Wells, Amy S. Turner, Jonathan R. Treadwell
Publikováno v:
Arthritis & Rheumatology.
Autor:
Christian Pagnoux, Antoine G. Sreih, David Cuthbertson, Curry L. Koening, Simon Carette, Kenneth J. Warrington, Nader Khalidi, Tanaz A. Kermani, Peter A. Merkel, Ulrich Specks, Larry W. Moreland, Philip Seo, Carol A. Langford, Carol A. McAlear, Paul A. Monach
Publikováno v:
Rheumatology (Oxford)
Objective To study the prevalence, risk and clinical associations of hypothyroidism among several forms of vasculitis. Methods Patients with GCA, Takayasu’s arteritis (TAK), PAN and the three forms of ANCA-associated vasculitis [AAV; granulomatosis