Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Larry Sai Weng Loo"'
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Stem cells possess the unique ability to differentiate into specialized cell types. These specialized cell types can be used for regenerative medicine purposes such as cell therapy. Myosatellite cells, also known as skeletal muscle stem cell
Externí odkaz:
https://doaj.org/article/36ce7a43c6614b639485cb4f70cfadcf
FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro
Autor:
Hwee Hui Lau, Nur Shabrina Amirruddin, Larry Sai Weng Loo, Jun Wei Chan, Elhadi Iich, Vidhya Gomathi Krishnan, Shawn Hoon, Adrian Kee Keong Teo
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107265- (2023)
Summary: The differentiation of human pluripotent stem cells into the SOX17+ definitive endoderm (DE) germ layer is important for generating tissues for regenerative medicine. Multiple developmental and stem cell studies have demonstrated that Activi
Externí odkaz:
https://doaj.org/article/153f3a71a5cf42f8b50ec86c660d7861
Autor:
Sean Chia, Gavin Teo, Shi Jie Tay, Larry Sai Weng Loo, Corrine Wan, Lyn Chiin Sim, Hanry Yu, Ian Walsh, Kuin Tian Pang
Publikováno v:
Foods, Vol 11, Iss 13, p 1952 (2022)
It is estimated that food fraud, where meat from different species is deceitfully labelled or contaminated, has cost the global food industry around USD 6.2 to USD 40 billion annually. To overcome this problem, novel and robust quantitative methods a
Externí odkaz:
https://doaj.org/article/b968a834d2da49eab9f08763ca04e40e
Autor:
Craig Jun Kit Wong, Yee Kit Tai, Jasmine Lye Yee Yap, Charlene Hui Hua Fong, Larry Sai Weng Loo, Marek Kukumberg, Jürg Fröhlich, Sitong Zhang, Jing Ze Li, Jiong-Wei Wang, Abdul Jalil Rufaihah, Alfredo Franco-Obregón
Publikováno v:
Biomaterials. 287
Pulsing electromagnetic fields (PEMFs) have been shown to promote in vitro and in vivo myogeneses via mitohormetic survival adaptations of which secretome activation is a key component. A single 10-min exposure of donor myoblast cultures to 1.5 mT am
Autor:
Hyungwon Choi, Xavier Roca, Larry Sai Weng Loo, Andreas Alvin Purnomo Soetedjo, Natasha Hui Jin Ng, Soumita Ghosh, Shawn Hoon, Adrian Kee Keong Teo, Vidhya Gomathi Krishnan, Linh Nguyen, Hwee Hui Lau
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 5, Pp 1-18 (2020)
Cell Death and Disease, Vol 11, Iss 5, Pp 1-18 (2020)
The differentiation of human pluripotent stem cells into pancreatic cells involves cellular proliferation and apoptosis during cell fate transitions. However, their implications for establishing cellular identity are unclear. Here, we profiled the ex
Autor:
Rohit N. Kulkarni, Steven P. Gygi, Andreas Alvin Purnomo Soetedjo, Adrian Kee Keong Teo, Yngvild Bjørlykke, Helge Ræder, Joanita Binte Jasmen, Larry Sai Weng Loo, Heidrun Vethe, Ivan Achel Valdez, Nicholas Jackson, Harald Barsnes, Joao A. Paulo, Marc Vaudel
Publikováno v:
Stem Cells
A comprehensive characterization of the molecular processes controlling cell fate decisions is essential to derive stable progenitors and terminally differentiated cells that are functional from human pluripotent stem cells (hPSCs). Here, we report t
Autor:
Linh Nguyen, Shawn Hoon, Larry Sai Weng Loo, Andreas Alvin Purnomo Soetedjo, Soumita Ghosh, Vidhya Gomathi Krishnan, Adrian Kee Keong Teo
Publikováno v:
Diabetes. 68
The differentiation of human pluripotent stem cells (hPSCs) into desired cell types such as the pancreatic cells involve cellular proliferation and apoptosis during cell fate transitions. Although different rates of cell growth and death are typicall
Autor:
Wei-Jun Qian, Chang Siang Lim, Manoj K. Gupta, Hwee Hui Lau, John L. Rinn, Marina A. Gritsenko, Larry Sai Weng Loo, William Mallard, Nicholas Jackson, Linh Nguyen, Richard D. Smith, Rohit N. Kulkarni, Adrian Kee Keong Teo
Publikováno v:
The Journal of Biological Chemistry
Human embryonic stem cells are a type of pluripotent stem cells (hPSCs) that are used to investigate their differentiation into diverse mature cell types for molecular studies. The mechanisms underlying insulin receptor (IR)-mediated signaling in the
Autor:
Hwee Hui Lau, Chang Siang Lim, Joanita Binte Jasmen, Larry Sai Weng Loo, Adrian Kee Keong Teo
Publikováno v:
Diabetes, obesitymetabolism. 20(1)
Type 1 and type 2 diabetes are caused by a destruction and decrease in the number of functional insulin-producing β cells, respectively; therefore, the generation of functional β cells from human embryonic stem cells and human induced pluripotent s