Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Larry S. Sherman"'
Autor:
Philip A. Adeniyi, Katie-Anne Fopiano, Fatima Banine, Mariel Garcia, Xi Gong, C. Dirk Keene, Larry S. Sherman, Zsolt Bagi, Stephen A. Back
Publikováno v:
ASN Neuro, Vol 14 (2022)
A major limitation of mechanistic studies in aging brains is the lack of routine methods to robustly visualize and discriminate the cellular distribution of tissue antigens using fluorescent immunohistochemical multi-labeling techniques. Although suc
Externí odkaz:
https://doaj.org/article/4eb214e7bf894f42a02fe9170c3f039e
Autor:
Aparna N. Govindan, Kristin S. Fitzpatrick, Minsha Manoharan, Ian Tagge, Steven G. Kohama, Betsy Ferguson, Samuel M. Peterson, Grayson S. Wong, William D. Rooney, Byung Park, Michael K. Axthelm, Dennis N. Bourdette, Larry S. Sherman, Scott W. Wong
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 2, Pp 456-470 (2021)
Abstract Objective To determine whether animals with Japanese macaque encephalomyelitis (JME), a spontaneous demyelinating disease similar to multiple sclerosis (MS), harbor myelin‐specific T cells in their central nervous system (CNS) and peripher
Externí odkaz:
https://doaj.org/article/e3983dd963594c35b1d381ed7a651083
Autor:
Larry S. Sherman, Weiping Su, Amanda L. Johnson, Samuel M. Peterson, Cassandra Cullin, Tiffany Lavinder, Betsy Ferguson, Anne D. Lewis
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105465- (2021)
Pelizaeus-Merzbacher disease (PMD) is a severe hypomyelinating disorder of the central nervous system (CNS) linked to mutations in the proteolipid protein-1 (PLP1) gene. Although there are multiple animal models of PMD, few of them fully mimic the hu
Externí odkaz:
https://doaj.org/article/2d2d3e20c3af4b85b3ae0e3f5c95a2cb
Autor:
Jodi L. McBride, Martha Neuringer, Betsy Ferguson, Steven G. Kohama, Ian J. Tagge, Robert C. Zweig, Laurie M. Renner, Trevor J. McGill, Jonathan Stoddard, Samuel Peterson, Weiping Su, Larry S. Sherman, Jacqueline S. Domire, Rebecca M. Ducore, Lois M. Colgin, Anne D. Lewis
Publikováno v:
Neurobiology of Disease, Vol 119, Iss , Pp 65-78 (2018)
We have identified a natural Japanese macaque model of the childhood neurodegenerative disorder neuronal ceroid lipofuscinosis, commonly known as Batten Disease, caused by a homozygous frameshift mutation in the CLN7 gene (CLN7−/−). Affected maca
Externí odkaz:
https://doaj.org/article/168900da9e314a49a97ffd11e624322e
Publikováno v:
International Journal of Cell Biology, Vol 2015 (2015)
Externí odkaz:
https://doaj.org/article/7205bfd3a9cf4a598d59a8c733a0b2d5
Publikováno v:
International Journal of Cell Biology, Vol 2015 (2015)
The glycosaminoglycan hyaluronan (HA), a component of the extracellular matrix, has been implicated in regulating neural differentiation, survival, proliferation, migration, and cell signaling in the mammalian central nervous system (CNS). HA is foun
Externí odkaz:
https://doaj.org/article/32a86055e86a463bb384995a8ede9480
Autor:
Krystal Ann Orlando, Amber K Douglas, Aierken Abudu, Yemin Wang, Basile Tessier-Cloutier, Weiping Su, Alec Peters, Larry S Sherman, Rayvon Moore, Vinh Nguyen, Gian Luca Negri, Shane Colborne, Gregg B Morin, Friedrich Kommoss, Jessica D Lang, William PD Hendricks, Elizabeth A Raupach, Patrick Pirrotte, David G Huntsman, Jeffrey M Trent, Joel S Parker, Jesse R Raab, Bernard E Weissman
Publikováno v:
eLife, Vol 9 (2020)
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare and aggressive form of ovarian cancer. SCCOHT tumors have inactivating mutations in SMARCA4 (BRG1), one of the two mutually exclusive ATPases of the SWI/SNF chromatin remodeling
Externí odkaz:
https://doaj.org/article/42b0954003194a36bc670b2a11181aaf
Autor:
Norah G Verbout, Weiping Su, Peter Pham, Kelley Jordan, Tia CL Kohs, Erik I Tucker, Owen JT McCarty, Larry S Sherman
Objective: Relapses in patients with relapsing-remitting multiple sclerosis (RRMS) are typically treated with high-dose corticosteroids including methylprednisolone. However, high-dose corticosteroids are associated with significant adverse effects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7aec55878f828eb974f415cbe635e50
https://doi.org/10.21203/rs.3.rs-2802415/v1
https://doi.org/10.21203/rs.3.rs-2802415/v1
Autor:
Zsolt Bagi, Christopher D. Kroenke, Katie Anne Fopiano, Yanna Tian, Jessica A. Filosa, Larry S. Sherman, Eric B. Larson, C. Dirk Keene, Kiera Degener O’Brien, Philip A. Adeniyi, Stephen A. Back
Publikováno v:
GeroScience
Patients with Alzheimer’s disease (AD) often have cerebral white matter (WM) hyperintensities on MRI and microinfarcts of presumed microvascular origin pathologically. Here, we determined if vasodilator dysfunction of WM-penetrating arterioles is a