Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Larry S. Abrams"'
Autor:
Geoffrey L. Hammond, Jaya Natarajan, Pentti K. Siiteri, George W. Creasy, Larry S. Abrams, J.Glyn Allen
Publikováno v:
Contraception. 67:93-99
Norelgestromin (NGMN) and levonorgestrel (LNG) are the main active metabolites of norgestimate (NGM), but their relative contributions to the pharmacological effects of NGM are unclear. We have therefore determined the serum distribution of these NGM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61472a7b15f9efe92746496102e22f1f
https://doi.org/10.1016/s0010-7824(02)00473-0
https://doi.org/10.1016/s0010-7824(02)00473-0
Publikováno v:
British Journal of Clinical Pharmacology. 53:141-146
Aims To determine the pharmacokinetic profile of norelgestromin (NGMN) and ethinyloestradiol (EE) following application of the contraceptive patch, Evra™/ Ortho Evra™, at each of four anatomic sites (abdomen, buttock, arm, and torso). Methods Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc4dfebcb9ea6ee2f6fd2ede0e033f4
https://doi.org/10.1046/j.0306-5251.2001.01532.x
https://doi.org/10.1046/j.0306-5251.2001.01532.x
Publikováno v:
The Journal of Clinical Pharmacology. 41:1232-1237
The primary objective of this open-label study was to determine the pharmacokinetics of norelgestromin (NGMN) and ethinyl estradiol (EE)following two consecutive applications of a contraceptive patch (ORTHO EVRA/EVRA). Twelve healthy women wore the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d035a1c7e24a271cb8ca0a86b0c90a41
https://doi.org/10.1177/00912700122012788
https://doi.org/10.1177/00912700122012788
Autor:
Lynnae K. Millar, Leslie North, T. Murphy Goodwin, Larry S. Abrams, Mary L. Holland, Raymond C. Weglein
Publikováno v:
American Journal of Obstetrics and Gynecology. 173:913-917
OBJECTIVE: Our purpose was to evaluate the pharmacokinetics of atosiban, an oxytocin antagonist, during and after intravenous infusion in pregnant patients having at least six contractions per hour. The relationship between atosiban infusion and uter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b3b2cd7057532634057a76736c5d27
https://doi.org/10.1016/0002-9378(95)90365-8
https://doi.org/10.1016/0002-9378(95)90365-8
Autor:
Brian M. Berger, Larry S. Abrams
Publikováno v:
Fertility and sterility. 93(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a76de49dc9600047e0bb7acccbbdfb
https://pubmed.ncbi.nlm.nih.gov/20100615
https://pubmed.ncbi.nlm.nih.gov/20100615
Publikováno v:
Fertility and sterility. 77(2 Suppl 2)
Objective: The pharmacokinetics of norelgestromin, the primary active metabolite of norgestimate, plus ethinyl estradiol (EE), delivered by the once-weekly contraceptive patch (Ortho Evra™/Evra™), have been studied in eight trials. This overview
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c835413fddb89bee6de3f2fcccaf54db
https://pubmed.ncbi.nlm.nih.gov/11849630
https://pubmed.ncbi.nlm.nih.gov/11849630
Autor:
Mona M. Shangold, Larry S. Abrams, Philip T. Leese, Donna Skee, Frankie A. Wong, Jaya Natarajan, George W Creasy
Publikováno v:
Journal of clinical pharmacology. 41(12)
The objectives of this randomized, open-label, three-period, incomplete block design study were to evaluate the pharmacokinetics of norelgestromin (NGMN) and ethinyl estradiol (EE) delivered by the contraceptive patch, Ortho Evra/Evra, and to evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc8b37a84240e69a9ec555d25bfda3b
https://pubmed.ncbi.nlm.nih.gov/11762557
https://pubmed.ncbi.nlm.nih.gov/11762557
Publikováno v:
Contraception. 64(5)
This open-label, randomized study evaluated the pharmacokinetics of norelgestromin (NGMN) and ethinyl estradiol (EE) following the application of a contraceptive patch (1/week) for three cycles (3 weeks/cycle). Healthy women (n = 24) wore a 20-cm(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2fde319d9fbe0c383d04d244e06c0b
https://pubmed.ncbi.nlm.nih.gov/11777488
https://pubmed.ncbi.nlm.nih.gov/11777488
Publikováno v:
Seminars in reproductive medicine. 19(4)
This review summarizes the clinical studies involving the once-weekly Ortho Evra/Evra contraceptive patch. The patch delivers norelgestromin (NGMN), 150 microg, and ethinyl estradiol (EE), 20 microg, daily to the systemic circulation. The contracepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b363b2122b4942511f089ffae8ceed4
https://pubmed.ncbi.nlm.nih.gov/11727179
https://pubmed.ncbi.nlm.nih.gov/11727179
Publikováno v:
Journal of pharmaceutical sciences. 67(10)
The disposition of radioactivity following oral administration of 14C-norgestimate was compared to that following administration of the drug in combination with 3H-ethinyl estradiol in humans. Seven normal, healthy female subjects were each administe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffcfd3f607db0ce8861a0708e32cf84
https://pubmed.ncbi.nlm.nih.gov/702290
https://pubmed.ncbi.nlm.nih.gov/702290