Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Larry S Eichmeier"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 15:513-521
A direct chiral HPLC method has been developed and validated to quantitate the enantiomers of MDL 74 156, the primary metabolite of dolasetron mesylate, in human plasma over the concentration range 1.70–340 ng ml−1. Dolasetron mesylate is a 5-HT3
Publikováno v:
Biomedical Chromatography. 6:295-299
A sensitive and selective liquid chromatographic method to quantitate MDL 201,012 in human plasma was developed and validated. MDL 201,012 (I), diethyl-MDL 201,012 (internal standard, II) and desmethyldiol-MDL 201,012 (masking agent, III) were isolat
Autor:
Robert C. Lanman, Bruce Morrill, Dennis H. Giesing, Michael B Lanman, Dale K Yu, Larry S Eichmeier, Alfred T Elvin
Publikováno v:
Clinical Pharmacology and Therapeutics. 48:26-33
Single doses of 1 gm 5-aminosalicylic acid (5-ASA) suspension was administered to 24 healthy volunteers during both fasting and fed conditions. For subjects in a fasting state, plasma 5-ASA and acetyl 5-ASA concentrations peaked rapidly 1 hour after
Publikováno v:
Biomedical chromatography : BMC. 8(5)
A sensitive and selective liquid chromatographic procedure to quantitate the deflazacort metabolite 21-hydroxy-deflazacort (DF-21OH) in human plasma was developed and validated. DF-21OH and fludrocortisone acetate (internal standard, IS) were isolate
Autor:
Michael E. Caplis, Larry S. Eichmeier
Publikováno v:
Analytical Chemistry. 47:841A-844a
Publikováno v:
Organic Mass Spectrometry. 20:247-252
The origin of the [M–69]+ and [M–111]+ signals in the mass spectrum of taraxasterol was studied through the use of C(18), (19), (21), (22) and/or (30) deuteriated derivatives. The generality of these signals for ring systems with an exocyclic met
Publikováno v:
Journal of Analytical Toxicology. 4:58-62
High pressure liquid chromatography procedures are reported for the determination of amitriptyline and its metabolite, nortriptyline, and for imipramine and its metabolite, desipramine. Separations and quantitations were carried out at ambient temper
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 20:1395-1405
Taraxasterols specifically labelled at various ring E sites were synthesized as were cyclohexanes and decalins substituted by a methyl group and an exocyclic methylene moiety similar to the ring Esystem of this terpene. Preparation of deuterated anal
Autor:
David M. Piatak, Larry S. Eichmeier
Publikováno v:
Phytochemistry. 11:436-438