Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Larry P. Thornburg"'
Autor:
Robert E. Smith, Richard A. Angelo, Larry P. Thornburg, Mark D. Murphey, Jamil W. Talhouk, James T. Palmer, Ronald E. Esser, Lynnetta M. Watts
Publikováno v:
Arthritis & Rheumatism. 37:236-247
Objective. To determine the effects of peptidyl fluoromethyl ketones on the in vitro activity of purified cathepsins B and L, on tissue cysteine proteinase activity, and on cartilage and bone destruction in experimental arthritis. Methods. The effect
Autor:
Jeff Prior, Lorene A. Martin, Larry P. Thornburg, Ronald E. Esser, Lynnetta M. Watts, Nahed K. Ahmed, Jim Palmer
Publikováno v:
Biochemical Pharmacology. 44:1201-1207
Peptidyl fluoromethyl ketones (FMKs), with the amino acid sequence Phe-Ala held constant but with variable N-terminal groups, were synthesized and tested for inhibition of the cysteine proteinase cathepsin B. The FMKs were effective in inhibiting cat
Autor:
Larry P. Thornburg
Publikováno v:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 12(2)
Copper is a ubiquitous trace metal necessary for normal function of a variety of cellular proteins. Intracellular copper metabolism is complex, and only a few of the proteins/genes involved are known. Copper deficiency does not appear to be a clinica
Publikováno v:
Histochemistry. 41:207-225
A new method is described for the direct cytochemical demonstration of lysosomal arylsulfatases utilizing a synthetic substrate, 4-nitro-1,2-benzenediol mono(hydrogen sulfate), and a copper capture reaction. A small amount of Hatchett's brown (cupric
Autor:
Jacob S. Hanker, Larry P. Thornburg
Publikováno v:
Acta Neuropathologica. 32:91-101
Selected lysosomal hydrolases have been investigated in the trigeminal ganglion of mice afflicted with an hereditary sensory neuropathy (dystonia musculorum). This was done using direct enzyme histochemistry. Correlative electron microscopy was also
Autor:
Larry P. Thornburg, Xiao Yan Zhou, Ranjit Ray, Robert Steele, Ratna B. Ray, Mainak Majumder, Nancy J. Phillips, Asish K. Ghosh
Publikováno v:
FEBS Letters. (3):528-532
Hepatitis C virus (HCV) is a major etiologic agent for chronic hepatitis worldwide often leading to the development of cirrhosis and hepatocellular carcinoma. However, the mechanism for development of chronic hepatitis or hepatocarcinogenesis by HCV
Autor:
William H. Fales, Everett Aronson, Larry P. Thornburg, Ron K. Fallon, Robert T. Franklin, S. L. Stockham
Publikováno v:
Veterinary Radiology. 26:211-213
An eight-year-old, female, spayed Golden Retriever was referred to the University of Missouri Veterinary Teaching Hospital for a persistent lameness of 9 days duration. The initial diagnosis made by cytology and culture was Clostridium spp osteomyeli
Autor:
Larry P. Thornburg
Publikováno v:
Veterinary Pathology. 19:461-462
Publikováno v:
The Journal of Zoo Animal Medicine. 19:143