Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Larry M Mallis"'
Autor:
Larry M Mallis, David Revelli, Steven A. Belinsky, Carmen S. Tellez, David T. Vodak, Thomas H. March, Michael Burke, Aaron M. Badenoch, Marcie J. Grimes, Philip J. Kuehl, Maria A. Picchi, Wendy W Dye, Devon B Dubose, Tyler Sniegowski, Mathewos Tessema
Publikováno v:
British Journal of Cancer
Background Epigenetic therapy through demethylation of 5-methylcytosine has been largely ineffective in treating lung cancer, most likely due to poor tissue distribution with oral or subcutaneous delivery of drugs such as 5-azacytidine (5AZA). An inh
Autor:
Sayed Elmarakby, Keating Kelly, Oliver J. McConnell, Li Shen, William DeMaio, Larry M. Mallis, Yingru Zhang, Appavu Chandrasekaran
Publikováno v:
Drug Metabolism and Disposition. 34:1283-1287
Tanaproget is a first-in-class nonsteroidal progesterone receptor agonist that is being investigated for use in contraception. A major in vitro and in vivo metabolite of tanaproget formed in humans was initially characterized as a glucuronide of tana
Publikováno v:
Journal of Chromatography B. 796:71-86
In recent years, consumption of herbal supplements as an alternative to pharmaceutical drug therapy has increased. For example, with the health claims labeling which describes the link between soy-protein and a reduced risk of coronary heart disease
Autor:
Darlene C. Deecher, Panayiotis E. Stevis, Larry M. Mallis, Donald E. Frail, Lorraine Suhadolnik
Publikováno v:
Endocrinology. 140:5455-5458
The steroid 17beta-estradiol (E2) acts to modulate transcription through classical nuclear estrogen receptors (ER-alpha and ER-beta). However, E2 also induces a number of rapid responses (
Publikováno v:
Inorganic Chemistry. 31:1816-1822
The reaction of (η 6 -Ca(CH 3 ) 6 )Mn(CO) 2 SC(S)H (1) with Ph 3 C + BF 4 - affords the adduct [(η 6 -Ca(CH 3 ) 6 )Mn(CO) 2 SCHSCPh 3 ] + BF 4
Analysis of glycosaminoglycan-derived oligosaccharides using fast-atom-bombardment mass-spectrometry
Publikováno v:
Carbohydrate Research. 225:137-145
Publikováno v:
Psychiatry Research. 37:261-270
In several previous studies, we reported significantly higher plasma serine concentrations in psychotic (and schizophrenic) subjects compared with nonpsychotic and control subjects. In those studies, we used a gas chromatopgraphy technique to assay t
Publikováno v:
Organometallics. 10:1026-1033
Initially observed as a minor product in the reaction of (η 6 -C 6 (CH 3 ) 6 )Mn(CO) 3 PF 6 (1) with KBH(OC-H(CH 3 ) 2 ) 3 , the title compound, (η 5 -C 6 (CH 3 ) 5 (CH 2 ))Mn(CO) 3 (2) has been synthesized and isolated in good yield by the reactio
Publikováno v:
Pharmaceutical Research. :1151-1154
Alpha- and beta-cyclodextrins and their hydroxypropyl derivatives were converted by the reaction with chlorosulfonic acid in pyridine to the corresponding sulfates. Cyclodextrin sulfates were shown by fast-atom bombardment mass spectrometry (negative
Autor:
Larry M. Mallis, William J. Scott
Publikováno v:
Organic Mass Spectrometry. 25:415-419
In an attempt to identify and characterize the intermediates involved in multi-step palladium catalyzed coupling reactions, under fast atom bombardment (FAB) conditions, the selection of a matrix to enhance ion formation without degrading the palladi