Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Larry M Jordan"'
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
There is considerable evidence from research in neonatal and adult rat and mouse preparations to warrant the conclusion that activation of 5-HT2 and 5-HT1A/7 receptors leads to activation of the spinal cord circuitry for locomotion. These receptors a
Externí odkaz:
https://doaj.org/article/019257edc268408ab2160d596b6d3cd7
Autor:
Larry M. Jordan, Urszula Sławińska
Publikováno v:
Current Opinion in Physiology. 8:63-69
Serotonin (5-HT) neurons can be activated from the Mesencephalic Locomotor Region (MLR) to produce release of 5-HT in the spinal cord, and MLR evoked locomotion can be blocked by a 5-HT7 receptor antagonist. 5-HT control shifts during development fro
Unusual Quadrupedal Locomotion in Rat during Recovery from Lumbar Spinal Blockade of 5-HT7 Receptors
Autor:
Anna Kwaśniewska, Malgorzata Zawadzka, Anna M. Cabaj, Marek Bekisz, Larry M. Jordan, Urszula Sławińska, Henryk Majczyński, Krzysztof Miazga
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6007, p 6007 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6007, p 6007 (2021)
Coordination of four-limb movements during quadrupedal locomotion is controlled by supraspinal monoaminergic descending pathways, among which serotoninergic ones play a crucial role. Here we investigated the locomotor pattern during recovery from blo
Publikováno v:
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 14 (2020)
Frontiers in Neural Circuits, Vol 14 (2020)
Applying serotonergic (5-HT) agonists or grafting of fetal serotonergic cells into the spinal cord improves locomotion after spinal cord injury. Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administer
Autor:
Malgorzata Zawadzka, Krzysztof Miazga, Hanna Fabczak, Larry M. Jordan, Anna Bejrowska, Marek Bekisz, Ewa Joachimiak, Łucja Krzemień-Ojak, Urszula Sławińska
Publikováno v:
Neural Plasticity
Neural Plasticity, Vol 2018 (2018)
Neural Plasticity, Vol 2018 (2018)
Serotonin (5-hydroxytryptamine; 5-HT) plays an important role in control of locomotion, partly through direct effects on motoneurons. Spinal cord complete transection (SCI) results in changes in 5-HT receptors on motoneurons that influence functional
Autor:
Dawn M. G. Johnson, Luz M. Villamil, Ioan Opris, Xiaohong Dai, Brian R. Noga, Francisco J. Sanchez, Cecelia R. Lee-Hauser, Larry M. Jordan, Songtao Xie, Stephano J. Chang
Publikováno v:
Frontiers in Systems Neuroscience, Vol 13 (2019)
Frontiers in Systems Neuroscience
Frontiers in Systems Neuroscience
The distribution of locomotor-activated neurons in the brainstem of the cat was studied by c-Fos immunohistochemistry in combination with antibody-based cellular phenotyping following electrical stimulation of the mesencephalic locomotor region (MLR)
Autor:
Katinka Stecina, Urszula Sławińska, Larry M. Jordan, Erika Couto, Phillip F. Gardiner, Anna M. Cabaj, Henryk Majczyński
Publikováno v:
The Journal of Physiology. 595:301-320
Key points Experiments on neonatal rodent spinal cord showed that serotonin (5-HT), acting via 5-HT7 receptors, is required for initiation of locomotion and for controlling the action of interneurons responsible for inter- and intralimb coordination,
Autor:
Urszula Sławińska, Henryk Majczyński, Anna Kwaśniewska, Larry M. Jordan, Krzysztof Miazga, Malgorzata Zawadzka
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5520, p 5520 (2020)
Volume 21
Issue 15
International Journal of Molecular Sciences, Vol 21, Iss 5520, p 5520 (2020)
Intraspinal grafting of serotonergic (5-HT) neurons was shown to restore plantar stepping in paraplegic rats. Here we asked whether neurons of other phenotypes contribute to the recovery. The experiments were performed on adult rats after spinal cord
Publikováno v:
Journal of neurophysiology. 120(4)
Cat lumbar motoneurons display changes in membrane properties during fictive locomotion. These changes include reduction of input resistance and afterhyperpolarization, hyperpolarization of voltage threshold, and voltage-dependent excitation of the m