Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Larry Ka-Yue Chow"'
Autor:
Lanqi Gong, Jie Luo, Yu Zhang, Yuma Yang, Shanshan Li, Xiaona Fang, Baifeng Zhang, Jiao Huang, Larry Ka-Yue Chow, Dittman Chung, Jinlin Huang, Cuicui Huang, Qin Liu, Lu Bai, Yuen Chak Tiu, Pingan Wu, Yan Wang, George Sai-Wah Tsao, Dora Lai-wan Kwong, Anne Wing-Mui Lee, Wei Dai, Xin-Yuan Guan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Response rates to immunotherapies in patients with nasopharyngeal carcinoma (NPC) are still limited. Here the authors show that tumor-restricted CD70 correlates with regulatory T cell abundance and suppressive activity in NPC and that CD70 blockade i
Externí odkaz:
https://doaj.org/article/b6da0bb5eab74ad7aa459a56759ab2ba
Autor:
Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Lihua Tao, Kui Fat Chan, Stewart Yuk Tung, Roger Kai Cheong Ngan, Wai Tong Ng, Anne Wing-Mui Lee, Chun Chung Yau, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, Ka-On Lam, Jiayan Liu, Honglin Chen, Wei Dai, Maria Li Lung
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104357- (2022)
Summary: Background: Epstein-Barr virus (EBV) latent infection is associated with genome-wide epigenomic changes in several malignancies, but its role in epigenetic dysregulation remains unclear in nasopharyngeal carcinoma (NPC). Methods: To investig
Externí odkaz:
https://doaj.org/article/2bc6dad55c7b4c878e2ab635d488677a
Autor:
Shirong Ding, Ying Gao, Dongming Lv, Yalan Tao, Songran Liu, Chen Chen, Zilu Huang, Shuohan Zheng, Yujun Hu, Larry Ka-Yue Chow, Yinghong Wei, Ping Feng, Wei Dai, Xin Wang, Yunfei Xia
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104100- (2022)
Summary: Background: Distant metastasis remains the leading cause of treatment failure in patients with nasopharyngeal carcinoma (NPC), making it critical to identify efficient therapeutic targets for metastatic NPC. Previous studies have demonstrate
Externí odkaz:
https://doaj.org/article/1ee86748ca9e498db8af2feaabb12f16
Autor:
Lanqi Gong, Dora Lai-Wan Kwong, Wei Dai, Pingan Wu, Shanshan Li, Qian Yan, Yu Zhang, Baifeng Zhang, Xiaona Fang, Li Liu, Min Luo, Beilei Liu, Larry Ka-Yue Chow, Qingyun Chen, Jinlin Huang, Victor Ho-Fun Lee, Ka-On Lam, Anthony Wing-Ip Lo, Zhiwei Chen, Yan Wang, Anne Wing-Mui Lee, Xin-Yuan Guan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The tumor microenvironment can influence patient survival response to therapy. Here, the authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identify tumor-specific signatures in five stromal clusters
Externí odkaz:
https://doaj.org/article/0b2c6fcf4f674aa2b645939100155c52
Autor:
Kazi Anisha Islam, Larry Ka-Yue Chow, Ngar Woon Kam, Ying Wang, Chi Leung Chiang, Horace Cheuk-Wai Choi, Yun-Fei Xia, Anne Wing-Mui Lee, Wai Tong Ng, Wei Dai
Publikováno v:
Cancers, Vol 14, Iss 9, p 2122 (2022)
This systematic review aims to identify prognostic molecular biomarkers which demonstrate strong evidence and a low risk of bias in predicting the survival of nasopharyngeal carcinoma (NPC) patients. The literature was searched for on PubMed to ident
Externí odkaz:
https://doaj.org/article/9a27abb4092b41bab22b7773135746c0
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Purpose:Investigation of biological mechanisms underlying genetic alterations in cancer can assist the understanding of etiology and identify the potential prognostic biomarkers.Experimental Design:We performed an integrative genomic analysis for a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854cd4a5cb32a8539f5b4cb7f03b1767
https://doi.org/10.1158/1078-0432.c.6529601
https://doi.org/10.1158/1078-0432.c.6529601
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Figure S5: Methylation of selected genes between NPC and adjacent non-tumor tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0111c0b88816fe22b7db067acf0a89d7
https://doi.org/10.1158/1078-0432.22477226
https://doi.org/10.1158/1078-0432.22477226
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772fbb15cd608c09857e2004815ad20c
https://doi.org/10.1158/1078-0432.22477217.v1
https://doi.org/10.1158/1078-0432.22477217.v1
Autor:
Maria Li Lung, Josephine Mun-Yee Ko, Candy King-Chi Chan, Merrin Man-Long Leong, Lisa Chan Lei, Valen Zhuoyou Yu, Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Wei Dai
Table S1: Clinical parameters for the HK-3 cohort for targeted sequencing (N=402);Table S2: Sample size estimation and power calculation for study cohorts;Table S3: Mutational signatures and clinical parameters in primary NPC (N=178);Table S4: All th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3472c73172f274d23c954c649dd3871
https://doi.org/10.1158/1078-0432.22477214
https://doi.org/10.1158/1078-0432.22477214
Publikováno v:
Cancer Research. 83:4716-4716
Background: Epstein-Barr virus (EBV) can be detected in more than 90% of NPC patients in Hong Kong. It has been shown that EBV infection could hijack the human epigenome in B cell lymphoma and EBV+ gastric cancer, however, the role of EBV in epigenet