Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Larry K. Wong"'
Improved rejection of multiply scattered photons in confocal microscopy using dual-axes architecture
Publikováno v:
Optics letters. 32(12)
We perform Monte Carlo simulations to show that the dual-axes (DA) confocal architecture has superior rejection of multiply scattered photons in tissue to that of single axis. As a result, the DA configuration provides improved signal-to-noise ratio
Autor:
Wibool Piyawattanametha, Thomas D. Wang, Olav Solgaard, Michael J. Mandella, Hyejun Ra, Gordon S. Kino, C.B. Du, Jonathan T. C. Liu, Larry K. Wong, Christopher H. Contag
Publikováno v:
TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference.
We demonstrate a novel microelectromechanical system (MEMS) based Dual-Axes confocal (DAC) microscope in a 10-mm diameter handheld package. Miniaturization is achieved by using a barbell-shaped, gimbaled, two-dimensional (2-D) MEMS scanner that is ac
Autor:
Wibool Piyawattanametha, Jonathan T. C. Liu, Michael J. Mandella, Larry K. Wong, Olav Solgaard, Hyejun Ra, Gordon S. Kino, Christopher H. Contag, Ting Wang
Publikováno v:
2007 Conference on Lasers and Electro-Optics (CLEO).
We demonstrate reflectance and fluorescence imaging with a handheld dual-axes confocal microscope based on a two-dimensional microelectromechanical system scanner. Three-dimensional imaging capability is shown in tissue, and in vivo imaging of a mous
Autor:
Wibool Piyawattanametha, Thomas D. Wang, Hyejun Ra, Olav Solgaard, Michael J. Mandella, Christopher H. Contag, Gordon S. Kino, Larry K. Wong, Jonathan T. C. Liu, Pei Lin Hsiung
Publikováno v:
SPIE Proceedings.
Here we describe a simple optical design for a MEMS-based dual-axes fiber optic confocal scanning microscope that has been miniaturized for handheld imaging of tissues, and which is capable of being further scaled to smaller dimensions for endoscope
Publikováno v:
SPIE Proceedings.
Tissue scattering has a significant effect on the image resolu tion and light collection efficiency in confocal microscopy. The dual-axes (DA) confocal architecture has many advantages including high axial resolution with low numerical aperture lense
Autor:
Larry K. Wong, Michael J. Mandella, Olav Solgaard, Gordon S. Kino, Wibool Piyawattanametha, Hyejun Ra, Jonathan T. C. Liu, Pei Lin Hsiung, Thomas D. Wang
Publikováno v:
IEEE/LEOS International Conference on Optical MEMS and Their Applications Conference, 2006..
We demonstrate a dual-axes confocal reflectance microscope in a 10-mm diameter handheld package. Miniaturization is achieved by using a barbell-shaped, gimbaled, two-dimensional MEMS scanner that is actuated by self-aligned vertical comb actuators. T
Autor:
Larry K. Wong, Olav Solgaard, Gordon S. Kino, Wibool Piyawattanametha, Christopher H. Contag, Hyejun Ra, Jonathan T. C. Liu, Michael J. Mandella, Thomas D. Wang
Publikováno v:
Optics Letters. 32:256
The first, to our knowledge, miniature dual-axes confocal microscope has been developed, with an outer diameter of 10 mm, for subsurface imaging of biological tissues with 5-7 microm resolution. Depth-resolved en face images are obtained at 30 frames