Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Larry J. Shampine"'
Autor:
Rajendra A. Morey, Sarah L. Davis, Courtney C. Haswell, Jennifer C. Naylor, Jason D. Kilts, Steven T. Szabo, Larry J. Shampine, Gillian J. Parke, Delin Sun, Chelsea A. Swanson, Henry R. Wagner, Mid-Atlantic MIRECC Workgroup, Christine E. Marx
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
BackgroundNeuroactive steroids are endogenous molecules with regenerative and neuroprotective actions. Both cortical thickness and many neuroactive steroid levels decline with age and are decreased in several neuropsychiatric disorders. However, a sy
Externí odkaz:
https://doaj.org/article/92e421589a49421eada6c07c94cef67a
Autor:
Kelly M. Mahar Doan, Cosette J. Serabjit-Singh, Joseph W. Polli, John Kratz, James P. Bishop, Kimberly K. Adkison, Eric Yang, Kelly H. Jordan, Stephen A. Wring, Larry J. Shampine
Publikováno v:
Pharmacology. 72:92-98
The purpose of this study was to measure the in vivo brain distribution of antihistamines and assess the influence of in vitro permeability, P-glycoprotein (Pgp) efflux, and plasma protein binding. Six antihistamines (acrivastine, chlorpheniramine, d
Autor:
Eric Yang, Kelly H. Jordan, M. Latorre, Stephen A. Wring, Markus Haisjackl, Shrinivas K. Kulkarni, Bruno K. Podesser, Kelly M. Mahar Doan, Meral Baka, Selvinaz Dalaklioglu, Eduardo Antônio Donadi, Jorge Camarasa, Seth Hallström, Aalt Bast, Utku Ateş, Cosette J. Serabjit-Singh, Naveen K. Jain, Altug Yavasoglu, J. Del Río, Harald Gasser, J.M. Bartolomé-Nebreda, Maximilian Franz, Josiane Cristófani Poggi, Philip Van Kerrebroeck, Huseyin Aktug, Antonio Farré, V. P. Singh, Tadeusz Malinski, Joseph W. Polli, Gulay Sadan, Yiğit Uyanıkgil, R. Herranz, Larry J. Shampine, Miriam Dambros, Chandrashekhar S. Patil, John Kratz, Erkan Lebe, Severin Semsroth, R. González-Muñiz, Vera Lucia Lanchote, Kimberly K. Adkison, Arda Tasatargil, E. Cenarruzabeitia, M.T. García-López, Martin Dworschak, James P. Bishop, Giuliano Rodrigo Barissa, M. Angels Fisas, Marina Lemos dos Reis, Gommert van Koeveringe, Elena Escubedo
Publikováno v:
Pharmacology. 72:128-156
Autor:
Lindsey O. Webster, Larry J. Shampine, Kelly M. Mahar Doan, Cosette J. Serabjit-Singh, Joan E. Humphreys, Joseph W. Polli, Stephen A. Wring, Kimberly K. Adkison
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:1029-1037
Membrane permeability and P-glycoprotein (Pgp) can be limiting factors for blood-brain barrier penetration. The objectives of this study were to determine whether there are differences in the in vitro permeability, Pgp substrate profiles, and physico