Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Larry J, Suva"'
Autor:
Claire Stenhouse, Katherine M. Halloran, Emily C. Hoskins, Robyn M. Moses, Guoyao Wu, Heewon Seo, Gregory A. Johnson, Larry J. Suva, Dana Gaddy, Fuller W. Bazer
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Tissue non-specific alkaline phosphatase (TNSALP; encoded by the ALPL gene) has a critical role in the postnatal regulation of phosphate homeostasis, yet how TNSALP activity and expression are regulated during pregnancy remain lar
Externí odkaz:
https://doaj.org/article/059d64e8adcc4536afb04484791aec85
Autor:
Claire Stenhouse, Makenzie G. Newton, Katherine M. Halloran, Robyn M. Moses, Nirvay Sah, Larry J. Suva, Fuller W. Bazer
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Recent evidence suggests important roles for progesterone (P4) and interferon tau in the regulation of calcium, phosphate, and vitamin D signaling in the uteri of pregnant sheep. However, the effects of P4 and estradiol (E2), with
Externí odkaz:
https://doaj.org/article/12060ebd58584292aa31f1ba2d1b0b7d
Autor:
Alexandra Denys, Allison Norman, Daniel S Perrien, Larry J Suva, Liz Simon, Lee S McDaniel, Tekeda Ferguson, Kim Pedersen, David Welsh, Patricia E Molina, Martin JJ Ronis
Publikováno v:
JBMR Plus, Vol 7, Iss 1, Pp n/a-n/a (2023)
ABSTRACT People living with HIV (PLWH) represent a vulnerable population to adverse musculoskeletal outcomes due to HIV infection, antiretroviral therapy (ART), and at‐risk alcohol use. Developing measures to prevent skeletal degeneration in this g
Externí odkaz:
https://doaj.org/article/c75d3fb7beb54c19b0f483bf671f032a
Autor:
Connor P. Dolan, Tae-Jung Yang, Katherine Zimmel, Felisha Imholt, Osama Qureshi, Alyssa Falck, Joshua Gregory, Macie Mayes, Kayla Ritchie, Hannah Koester, Benjamin Daniel, Mingquan Yan, Ling Yu, Larry J. Suva, Dana Gaddy, Lindsay A. Dawson, Ken Muneoka, Regina Brunauer
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Structural regeneration of amputated appendages by blastema-mediated, epimorphic regeneration is a process whose mechanisms are beginning to be employed for inducing regeneration. While epimorphic regeneration is classically studi
Externí odkaz:
https://doaj.org/article/70345e430d4741d68396046541651079
Autor:
Claire Stenhouse, Katherine M. Halloran, Amelia R. Tanner, Larry J. Suva, Paul J. Rozance, Russell V. Anthony, Fuller W. Bazer
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7795 (2022)
Minerals are required for the establishment and maintenance of pregnancy and regulation of fetal growth in mammals. Lentiviral-mediated RNA interference (RNAi) of chorionic somatomammotropin hormone (CSH) results in both an intrauterine growth restri
Externí odkaz:
https://doaj.org/article/699b45eefb3f498dbb7f18337d7013f6
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-7 (2019)
Abstract Background Bisphosphonates (BPs) are a family of molecules characterized by two key properties: their ability to bind strongly to bone mineral and their inhibitory effects on mature osteoclasts and thus bone resorption. Chemically two groups
Externí odkaz:
https://doaj.org/article/1e6238d214f141d5b2107b1073d3a2f7
Autor:
Paulina D. Ketcham, Felisha Imholt, Mingquan Yan, Hannah M. Smith, Shabistan Asrar, Ling Yu, Connor P. Dolan, Osama Qureshi, Yu‐Lieh Lin, Ian Xia, Patrick C. Hall, Alyssa R. Falck, Kirby M. Sherman, Dana Gaddy, Larry J. Suva, Ken Muneoka, Regina Brunauer, Lindsay A. Dawson
Publikováno v:
Wound Repair and Regeneration. 31:17-27
Humans and mice have the ability to regenerate the distal digit tip, the terminal phalanx (P3) in response to amputation. What distinguishes P3 regeneration from regenerative failure is formation of the blastema, a proliferative structure that underg
Publikováno v:
Journal of Bone Oncology, Vol 12, Iss , Pp 19-22 (2018)
The 5TGM1 multiple myeloma transplanted C57BL6/KaLwRij model recapitulates many disease features including monoclonal paraprotein production as well as the development of osteolytic bone lesions. Since a significant association between serum parathyr
Externí odkaz:
https://doaj.org/article/03c3d551886542a3b361515fd8aa4b33
Publikováno v:
Journal of Bone Oncology, Vol 18, Iss , Pp - (2019)
Bisphosphonates are commonly used in patients with metastatic bone disease to prevent skeletal related events. Atypical femur fracture is a known complication of long-term bisphosphonate use but the incidence in cancer patients and pathogenesis are n
Externí odkaz:
https://doaj.org/article/964962200fa04fcaaee467f74ecee853
Autor:
Fatma F. Mohamed, Michael B. Chavez, Shannon Huggins, Joshua Bertels, Alyssa Falck, Larry J. Suva, Brian L. Foster, Dana Gaddy
Publikováno v:
Journal of Bone and Mineral Research. 37:2005-2017
Hypophosphatasia (HPP) is the inherited error-of-metabolism caused by mutations in ALPL, reducing the function of tissue-nonspecific alkaline phosphatase (TNAP/TNALP/TNSALP). HPP is characterized by defective skeletal and dental mineralization and is