Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Larry Iben"'
Autor:
Brian R. Anderson, Marianne L. Jensen, Peter H. Hagedorn, Sean C. Little, Richard E. Olson, Ron Ammar, Bernadette Kienzle, John Thompson, Ivar McDonald, Stephen Mercer, Jonas Vikesaa, Bettina Nordbo, Larry Iben, Yang Cao, Joanne Natale, Greg Dalton-Kay, Angela Cacace, Bo R. Hansen, Maj Hedtjärn, Troels Koch, Linda J. Bristow
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss , Pp 1290-1298 (2020)
Hundreds of dominant-negative myosin mutations have been identified that lead to hypertrophic cardiomyopathy, and the biomechanical link between mutation and disease is heterogeneous across this patient population. To increase the therapeutic feasibi
Externí odkaz:
https://doaj.org/article/ebaf673f331045b1903490834433fa8c
Autor:
Bo Hansen, Brian R. Anderson, Linda J. Bristow, Jonas Vikesaa, Sean C. Little, JoAnne E Natale, Maj Hedtjarn, Greg Dalton-Kay, John Ryan Thompson, Yang Cao, Peter Hagedorn, Marianne Lerbech Jensen, Ivar M. McDonald, Bernadette Kienzle, Larry Iben, Stephen E. Mercer, Bettina Nordbo, Angela Cacace, Troels Koch, Richard E. Olson, Ron Ammar
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss, Pp 1290-1298 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Hundreds of dominant-negative myosin mutations have been identified that lead to hypertrophic cardiomyopathy, and the biomechanical link between mutation and disease is heterogeneous across this patient population. To increase the therapeutic feasibi
Autor:
Lisa M. Kopcho, Kim Lentz, Alan Lin, Larry Iben, Lorin A. Thompson, John E. Macor, Michael J. Ford, James E. Grace, Charles F. Albright, Larry R. Marcin, Craig Polson, Dieter M. Drexler, Jovita Marcinkeviciene, Jeremy H. Toyn, Jere E. Meredith, Kelli M. Jones, Maria Pierdomenico, Tracey Fiedler, Donna M. Barten, Valerie Guss, Catherine R. Burton, Jason A. Corsa, Young B. Kim, Janet Kolb, Joe Cantone
Publikováno v:
Alzheimer's & Dementia. 4
Autor:
Scott W. Martin, Rachel T. McGovern, Graham S. Poindexter, Meredith Arcuri, Ildiko Antal-Zimanyi, Eric M. Parker, Ivo Monkovic, Jennifer A. Stanley, Larry Iben, Marc Bruce, Karen Leboulluec, Astrid A. Ortiz, Michael R. Kozlowski, Gail K. Mattson
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(3)
Dihydropyridine 5a was found to be an inhibitor of neuropeptide Y(1) binding in a high throughput (125)I-PYY screening assay. Structure-activity studies around certain portions of the dihydropyridine chemotype identified BMS-193885 (6e) as a potent a