Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Larry Gelbert"'
Publikováno v:
Journal of Biological Chemistry. 276:11199-11203
Human protein C is a natural anticoagulant factor, and a recombinant activated form of the molecule (rhAPC) is completing clinical evaluation for treatment of severe sepsis. Because of the pathophysiologic role of endothelial dysfunction in severe in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731f21cad3095cd1784011a9d005560a
https://doi.org/10.1074/jbc.c100017200
https://doi.org/10.1074/jbc.c100017200
Autor:
Patrice Jean, Nikolai Kley, Jana Laidlaw, Bernd R. Seizinger, Randy Talbott, Leonard Buckbinder, Larry Gelbert, Susana Velasco-Miguel
Publikováno v:
Oncogene. 18:127-137
Exposure of mammalian cells to hypoxia, radiation and certain chemotherapeutic agents promotes cell cycle arrest and/or apoptosis. Activation of p53 responsive genes is believed to play an important role in mediating such responses. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bab8745573d2d823d9efa0c7d44baad
https://doi.org/10.1038/sj.onc.1202274
https://doi.org/10.1038/sj.onc.1202274
Autor:
Harlan E. Shannon, Larry Gelbert, Christopher N. Batuello, Barbara J. Bailey, Karen E. Pollok, Katarzyna Kania
Publikováno v:
Neuro-Oncology. 16:v84-v85
Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. In high-risk NB, the MYCN gene is amplified in approximately 25% of all cases, and is considered to be a negative prognostic factor. MYCN can transcriptionally activate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdf44a95ce9704b4562f57c70b24479
https://doi.org/10.1093/neuonc/nou255.25
https://doi.org/10.1093/neuonc/nou255.25
Publikováno v:
Human Molecular Genetics. 2:925-931
Germ-line mutations in the adenomatous polyposis coli (APC) gene result in familial adenomatous polyposis coli (APC), an inherited syndrome that predisposes affected individuals to early onset of colorectal cancer. Somatic APC mutations also have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42f0b691dd18f8cf9ee9e9afedf67f5
https://doi.org/10.1093/hmg/2.7.925
https://doi.org/10.1093/hmg/2.7.925
Autor:
Nikolai Kley, Yan Chen, Larry Gelbert, Susana Velasco-Miguel, Jizong Gao, Bernd R. Seizinger, J. Silvio Gutkind, Ningzhi Xu, Leonard Buckbinder, Randy Talbott
Heterotrimeric G proteins transduce multiple growth-factor-receptor-initiated and intracellular signals that may lead to activation of the mitogen-activated or stress-activated protein kinases. Herein we report on the identification of a novel p53 ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324013fa62dc9a189f87e541b6774a4e
https://europepmc.org/articles/PMC21521/
https://europepmc.org/articles/PMC21521/
Autor:
Harry Drabkin, Harald Jüppner, Larry Gelbert, Gino V. Segre, Abdul B. Abou-Samra, Hunter Heath, Susan Naylor, Ernestina Schipani
Publikováno v:
The Journal of clinical endocrinology and metabolism. 79(4)
The human PTH/PTH-related peptide (PTH/PTHrP) receptor could be involved in hereditary disorders of PTH or PTHrP action. Knowledge of the gene's chromosomal location would allow studies linking it to specific disease traits. Therefore, we mapped the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfbddbbde21a267f2971f0468c10169
https://pubmed.ncbi.nlm.nih.gov/7962272
https://pubmed.ncbi.nlm.nih.gov/7962272
Publikováno v:
Copeia. 1998:411
Primers designed to amplify four microsatellite loci were used to screen 32 timber rattlesnakes (Crotalus horridus) representing five geographically distinct hiberacula within a 6000-ha area. Average heterozygosity at these loci approached 50% for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::451688463c8cc2163ea7cd12e4ff9a1f
https://doi.org/10.2307/1447435
https://doi.org/10.2307/1447435